[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100146825":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":36,"centralContacts":11,"locations":41,"responsibleParty":220,"collaborators":222,"id":227,"slug":228,"hasResults":229,"nctId":230,"briefTitle":231,"officialTitle":11,"acronym":11,"eligibilityCriteria":232,"healthyVolunteers":229,"sex":233,"minAge":234,"maxAge":235,"enrollmentInfo":236,"targetDuration":11,"studyType":239,"phases":240,"briefSummary":242,"conditions":243,"keywords":245,"overallStatus":250,"whyStopped":11,"lastUpdateSubmitDate":251,"lastUpdatePostDateStruct":252,"startDateStruct":255,"completionDateStruct":257,"leadSponsor":259,"locationsCount":260},{"fullName":5,"class":6},"The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Western therapy","ACTIVE_COMPARATOR",null,[13],"Other: Western therapy",{"label":15,"type":16,"description":11,"interventionNames":17},"TCM treatment","EXPERIMENTAL",[18],"Drug: TCM Syndrome Differentiation and Treatment",{"label":20,"type":16,"description":21,"interventionNames":22},"Western therapy plus TCM treatment","The combination of both western therapy and TCM treatment.",[23],"Other: Western therapy plus TCM treatment",[25,28,33],{"type":6,"name":9,"description":26,"armGroupLabels":27,"otherNames":11},"Symptomatic treatment: vitamin B, vitamin C, mouth care and skin care.\n\n1. Adopting physical cooling therapy, including physical cooling paste or warm bathing, when patient's body temperature is lower than 38.5 degree Celsius;\n2. Using Ibuprofen suspension when patient's temperature higher than 38.5 degree Celsius;",[9],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":11},"DRUG","TCM Syndrome Differentiation and Treatment","1. Lung-Spleen Damp-Heat Syndrome Symptoms: Fever, maculopapule and herpes on hand, foot and buttock; herpes on oral mucous membrane; redness in throat, salivation, tiredness, faint red tongue or reddish tongue, greasy fur, speedy pulse, red and purple fingerprint.\n\n   Formula: Forsythia suspensa (Thunb.) vahl.(Lian Qiao), Lonicera japonica Thunb (Jin Yin Hua), Scutellaria baicalensis Georgi (Huang Qin), etc.\n\n   Dosage: Adjusting by age and weight of patients. Decoction.\n2. Dampness-Heat Retention Syndrome Symptoms: High fever, dirty color of tetter, tiredness, oral ulcer, reddish tongue or deep red tongue, little saliva, yellow and greasy fur, fine and rapid pulse, deep purple fingerprint.\n\nFormula: Forsythia suspensa (Thunb.) vahl.(Lian Qiao), Gardenia jasminoides Ellis (rough Zhi Zi), Scutellaria baicalensis Georgi (Huang Qin), etc.\n\nDosage: Adjusting by age and weight of patients. Decoction.",[15],{"type":6,"name":20,"description":34,"armGroupLabels":35,"otherNames":11},"1. Symptomatic treatment using the same treatment methods in western therapy group;\n2. Syndrome differentiation and treatment adopting the same methods in TCM treatment group.",[20],[37],{"name":38,"affiliation":39,"role":40},"Guoliang Zhang","An'Hui Chinese Medical College Affiliated No.1 Hospital","PRINCIPAL_INVESTIGATOR",[42,54,59,68,73,82,91,99,108,117,126,135,144,153,162,171,180,189,198,202,211],{"facility":43,"status":11,"city":44,"state":45,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":11},"Anhui Provincial Children's Hospital","Hefei","Anhui","China","CN",{"type":49,"coordinates":50},"Point",[51,52],117.28083,31.86389,{"lat":52,"lon":51},{"facility":55,"status":11,"city":44,"state":45,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":56,"geoPoint":58,"contacts":11},"The First Affiliated Hospital of Anhui College of Traditional Chinese Medicine",{"type":49,"coordinates":57},[51,52],{"lat":52,"lon":51},{"facility":60,"status":11,"city":61,"state":62,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":63,"geoPoint":67,"contacts":11},"Beijing Ditan Hospital","Beijing","Beijing Municipality",{"type":49,"coordinates":64},[65,66],116.39723,39.9075,{"lat":66,"lon":65},{"facility":69,"status":11,"city":61,"state":62,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":70,"geoPoint":72,"contacts":11},"Beijing You-An Hospital",{"type":49,"coordinates":71},[65,66],{"lat":66,"lon":65},{"facility":74,"status":11,"city":75,"state":76,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":77,"geoPoint":81,"contacts":11},"Chongqing Hospital of Traditional Chinese Medicine","Chongqing","Chongqing Municipality",{"type":49,"coordinates":78},[79,80],106.55771,29.56026,{"lat":80,"lon":79},{"facility":83,"status":11,"city":84,"state":85,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":86,"geoPoint":90,"contacts":11},"Fuzhou Infectious Disease Hospital","Fuzhou","Fujian",{"type":49,"coordinates":87},[88,89],119.30611,26.06139,{"lat":89,"lon":88},{"facility":92,"status":11,"city":93,"state":85,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":94,"geoPoint":98,"contacts":11},"Xiamen Hospital of Traditional Chinese Medicine","Xiamen",{"type":49,"coordinates":95},[96,97],118.08187,24.47979,{"lat":97,"lon":96},{"facility":100,"status":11,"city":101,"state":102,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":103,"geoPoint":107,"contacts":11},"First Hospital of Lanzhou University","Lanzhou","Gausu",{"type":49,"coordinates":104},[105,106],103.83987,36.05701,{"lat":106,"lon":105},{"facility":109,"status":11,"city":110,"state":111,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":112,"geoPoint":116,"contacts":11},"Shenzhen Third People's Hospital","Shenzhen","Guangzhou",{"type":49,"coordinates":113},[114,115],114.0683,22.54554,{"lat":115,"lon":114},{"facility":118,"status":11,"city":119,"state":120,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":121,"geoPoint":125,"contacts":11},"The Fifth Hospital of Shijiazhuang, Hebei","Shijiazhuang","Hebei",{"type":49,"coordinates":122},[123,124],114.47861,38.04139,{"lat":124,"lon":123},{"facility":127,"status":11,"city":128,"state":129,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":130,"geoPoint":134,"contacts":11},"Wuhan Hospital for Infectious Diseases","Wuhan","Hubei",{"type":49,"coordinates":131},[132,133],114.26667,30.58333,{"lat":133,"lon":132},{"facility":136,"status":11,"city":137,"state":138,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":139,"geoPoint":143,"contacts":11},"Huhehaote Second Hospital","Hohhot","Inner Mongolia",{"type":49,"coordinates":140},[141,142],111.65222,40.81056,{"lat":142,"lon":141},{"facility":145,"status":11,"city":146,"state":147,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":148,"geoPoint":152,"contacts":11},"Ninth Hospital of Nanchang","Nanchang","Jiangxi",{"type":49,"coordinates":149},[150,151],115.85306,28.68396,{"lat":151,"lon":150},{"facility":154,"status":11,"city":155,"state":156,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":157,"geoPoint":161,"contacts":11},"Changchun Infectious Diseases Hospital","Changchun","Jilin",{"type":49,"coordinates":158},[159,160],125.32278,43.88,{"lat":160,"lon":159},{"facility":163,"status":11,"city":164,"state":165,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":166,"geoPoint":170,"contacts":11},"Ningxia Hui Autonomous Region Forth People's Hospital","Yinchuan","Ningxia Hui Autonomous",{"type":49,"coordinates":167},[168,169],106.27306,38.46806,{"lat":169,"lon":168},{"facility":172,"status":11,"city":173,"state":174,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":175,"geoPoint":179,"contacts":11},"The Eighth Hospital of Xi'an City","Xi'an","Shaanxi",{"type":49,"coordinates":176},[177,178],108.92861,34.25833,{"lat":178,"lon":177},{"facility":181,"status":11,"city":182,"state":183,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":184,"geoPoint":188,"contacts":11},"Shanghai Public Health Center","Shanghai","Shanghai Municipality",{"type":49,"coordinates":185},[186,187],121.45806,31.22222,{"lat":187,"lon":186},{"facility":190,"status":11,"city":191,"state":192,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":193,"geoPoint":197,"contacts":11},"Chengdu Hospital for Infectious Diseases","Chengdu","Sichuan",{"type":49,"coordinates":194},[195,196],104.06667,30.66667,{"lat":196,"lon":195},{"facility":199,"status":11,"city":200,"state":201,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":11,"geoPoint":11,"contacts":11},"Xinjiang Hongxing Hospital","Urumuqi","Xinjiang",{"facility":203,"status":11,"city":204,"state":205,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":206,"geoPoint":210,"contacts":11},"First Affiliated Hospital to Kunming Medical College","Kunming","Yunnan",{"type":49,"coordinates":207},[208,209],102.71833,25.03889,{"lat":209,"lon":208},{"facility":212,"status":11,"city":213,"state":214,"zip":11,"country":46,"countryCode":47,"cosmosGeoPoint":215,"geoPoint":219,"contacts":11},"The Sixth People's Hospital of Hangzhou","Hangzhou","Zhejiang",{"type":49,"coordinates":216},[217,218],120.16142,30.29365,{"lat":218,"lon":217},{"type":40,"investigatorFullName":38,"investigatorTitle":221,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Chief",[223,225],{"name":224,"class":6},"Beijing University of Chinese Medicine",{"name":226,"class":6},"China Academy of Chinese Medical Sciences","100146825","a-clinical-trial-to-evaluate-the-effectiveness-and-safety-of-chinese-medicine-in-the-treatment-of-mild-type-of-hand-foot-and-mouth-disease-100146825",false,"NCT01182532","A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth Disease","Inclusion Criteria:\n\n* Clinical diagnosis of severe hand-foot-mouth disease patients according to Hand-Foot-Mouth Disease Treatment Guidelines 2010 issued by China's Ministry of Health; More than 1\u002F3 patients should be diagnosed by etiological examination.\n* Less than 48 hours of occurrence of fever and\u002For occurrence of tetter or herpes.\n* Age of 1-14 years.\n* Patients or their guardians agree to participate in this study and signed the informed consent form.\n\nExclusion Criteria:\n\n* Complicated with other serious primary diseases in organ such as congenital heart disease, chronic hepatitis, nephritis and blood diseases, etc.\n* With history of allergies on traditional Chinese medicine.\n* Patients or their guardians suffering from Psychiatric diseases.\n* Attending other clinical studies on HFMD after diagnosed.","ALL","1 Year","14 Years",{"count":237,"type":238},3000,"ACTUAL","INTERVENTIONAL",[241],"NA","The study is aimed to evaluate the effectiveness and safety of traditional Chinese medicine (TCM) for treatment of hand, foot, and mouth disease (HFMD).",[244],"Hand, Foot and Mouth Disease",[246,247,248,249],"Mild type of hand, foot and mouth disease","Traditional Chinese Medicine","Effectiveness","Safety","COMPLETED","2012-07-20",{"date":253,"type":254},"2012-07-23","ESTIMATED",{"date":256,"type":11},"2010-05",{"date":258,"type":238},"2011-12",{"name":5,"class":6},21]