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39610","Zaragoza","50009",{"type":28,"coordinates":207},[208,209],-0.87734,41.65606,{"lat":209,"lon":208},{"type":212,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[214],{"name":215,"class":216},"Demométrica","UNKNOWN","100145080","a-comparison-of-body-fat-distribution-in-hiv-1-infected-patients-receiving-since-the-beginning-and-for-at-least-two-years-an-antiretroviral-therapy-based-on-efavirenz-or-lopinavirritonavir-combined-with-tenofovir--emtricitabine-or-lamivudine-100145080",true,"NCT01159743","A Comparison of Body Fat Distribution in HIV-1 Infected Patients Receiving, Since the Beginning and for at Least Two Years, an Antiretroviral Therapy Based on Efavirenz or Lopinavir\u002FRitonavir Combined With Tenofovir + Emtricitabine or Lamivudine","LYNX","Inclusion Criteria\n\n* Men and women aged ≥ 18 years with HIV-1 infection who are clinically stable and who were invited to participate in the study at a routine follow-up visit.\n* HIV-1 infected patients receiving since the beginning and continuously, for at least two years, initial antiretroviral therapy (ART) based on efavirenz (EFV) and a combination of tenofovir (TDF) + emtricitabine (FTC) \\[or lamivudine (3TC)\\] or HIV-1 infected patients receiving since the beginning and continuously, for at least two years, initial ART based on lopinavir\u002Fritonavir (LPV\u002Fr) and a combination of TDF +FTC (or 3TC).\n* Patients with an undetectable viral load, in response to the detection limit of each participating hospital defined in the last 6 months.\n* Patients who have given written informed consent to participate in this study \\[personal data collection and performance of dual energy X-ray absorptiometry (DEXA)\\].\n\nExclusion Criteria\n\n* Patients who have received at some point both efavirenz (EFV) and lopinavir\u002Fritonavir (LPV\u002Fr) in combination regimen or thereafter.\n* Patients who have had structured treatment interruptions (therapeutic holidays).\n* Patients with a body mass index \\\u003C16 kg\u002Fm\\^2.\n* Patients with metallic prostheses or prosthetic material that could interfere with the measurement of dual energy X-ray absorptiometry (DEXA).\n* Patients with a history of plastic or repair surgery in the buttocks and breasts.\n* Patients with a diagnostic test with barium or radionucleotides, performed during the last month.\n* Pregnant women.\n* Patients treated with other agents under investigational phase.\n* Patients on current treatment with systemic corticosteroids or chemotherapy.\n* Diabetes mellitus and hypoglycaemic treatment.\n* Transsexualism (though implicit in prostheses and drugs).\n* Any drug taken chronically, which may alter the distribution of fat or adipocyte biology (insulin, non-steroidal anti-inflammatory drugs, etc).\n* Patient has undergone liposuction.",false,"ALL","18 Years",{"count":228,"type":229},346,"ACTUAL","OBSERVATIONAL","The purpose of this study is 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