[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100498055":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":11,"centralContacts":11,"locations":45,"responsibleParty":59,"collaborators":11,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":11,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":11,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":11,"overallStatus":82,"whyStopped":11,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Beijing Ditan Hospital","OTHER",[8,14,18,23],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment Group 1","EXPERIMENTAL",null,[13],"Drug: HH-120 nasal spray 1",{"label":15,"type":10,"description":11,"interventionNames":16},"Treatment Group 2",[17],"Drug: HH-120 nasal spray 2",{"label":19,"type":20,"description":11,"interventionNames":21},"Control Group 3","PLACEBO_COMPARATOR",[22],"Drug: Placebo Comparator 1",{"label":24,"type":20,"description":11,"interventionNames":25},"Control Group 4",[26],"Drug: Placebo Comparator 2",[28,33,37,41],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":11},"DRUG","HH-120 nasal spray 1","HH-120 nasal spray 5 times daily for 3 consecutive days",[9],{"type":29,"name":34,"description":35,"armGroupLabels":36,"otherNames":11},"HH-120 nasal spray 2","HH-120 nasal spray 8 times daily for 3 consecutive days",[15],{"type":29,"name":38,"description":39,"armGroupLabels":40,"otherNames":11},"Placebo Comparator 1","Placebo nasal spray 5 times daily for 3 consecutive days",[19],{"type":29,"name":42,"description":43,"armGroupLabels":44,"otherNames":11},"Placebo Comparator 2","Placebo nasal spray 8 times daily for 3 consecutive days",[24],[46],{"facility":47,"status":11,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":11},"Beijing Ditan Hospital,Capital Medical University","Beijing","Beijing Municipality","100015","China","CN",{"type":54,"coordinates":55},"Point",[56,57],116.39723,39.9075,{"lat":57,"lon":56},{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Ronghua Jin","Professor","100498055","a-study-to-assess-the-efficacy-of-hh-120-nasal-spray-for-prevention-of-sars-cov-2-infection-in-adult-close-contacts-of-individuals-infected-with-sars-cov-2-100498055",false,"NCT05765279","A Study to Assess the Efficacy of HH-120 Nasal Spray for Prevention of SARS-CoV-2 Infection in Adult Close Contacts of Individuals Infected With SARS-CoV-2","An Investigator Initiated Clinical Study To Evaluate the Efficacy and Safety of HH-120 Nasal Spray as Post Exposure Prophylaxis (PEP) Regimen in Adult Close Contacts of Individuals Infected With SARS-CoV-2","Inclusion Criteria:\n\n* Participants aged 18 to 65 years.\n* Participants who have close contact with a SARS-CoV-2 infected individual (index case) are required to be randomized within 72 hours upon close contact.\n* Willing and able to provide written informed consent, or with a legal representative who can provide informed consent.\n\nExclusion Criteria:\n\n* Have a history of severe allergy or hyper-sensitivity to inhaled allergen.\n* Pregnant or breastfeeding women.\n* Have participated, within the last 180 days prior to the screening, in a clinical study involving an investigational intervention of SARS-CoV-2 neutralizing antibody.\n* Have other conditions not suitable for the study per investigator's discretion.","ALL","18 Years","65 Years",{"count":74,"type":75},281,"ACTUAL","INTERVENTIONAL",[78],"NA","An Investigator-initiated, Randomized, Single-Blind, Placebo-Controlled Trial to Evaluate the Efficacy of SARS-Cov-2 Post Exposure Prophylaxis and Safety of HH-120 nasal spray",[81],"SARS-CoV-2 Infection","COMPLETED","2023-03-01",{"date":85,"type":75},"2023-03-13",{"date":87,"type":75},"2022-10-20",{"date":89,"type":75},"2022-12-06",{"name":5,"class":6},1]