[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100134410":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":7,"locations":15,"responsibleParty":35,"collaborators":37,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":7,"eligibilityCriteria":44,"healthyVolunteers":45,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":7,"studyType":52,"phases":7,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":63,"whyStopped":7,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Cornell University","OTHER",null,[9,12],{"name":10,"affiliation":5,"role":11},"Kimberly O O'Brien, PhD","PRINCIPAL_INVESTIGATOR",{"name":13,"affiliation":14,"role":11},"Eva Pressman, MD","University of Rochester",[16,29],{"facility":17,"status":7,"city":18,"state":19,"zip":20,"country":21,"countryCode":22,"cosmosGeoPoint":23,"geoPoint":28,"contacts":7},"Highland Hospital","Rochester","New York","14620","United States","US",{"type":24,"coordinates":25},"Point",[26,27],-77.61556,43.15478,{"lat":27,"lon":26},{"facility":30,"status":7,"city":18,"state":19,"zip":31,"country":21,"countryCode":22,"cosmosGeoPoint":32,"geoPoint":34,"contacts":7},"Strong Memorial Hospital","14642",{"type":24,"coordinates":33},[26,27],{"lat":27,"lon":26},{"type":36,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[38],{"name":14,"class":6},"100134410","absorption-of-heme-and-non-heme-iron-in-pregnant-and-non-pregnant-women-and-mechanisms-of-fetal-iron-transfer-100134410",false,"NCT01019096","Absorption of Heme and Non-Heme Iron in Pregnant and Non-pregnant Women and Mechanisms of Fetal Iron Transfer","Inclusion Criteria:\n\n* Pregnant subjects (15-35 yrs): non-smoking,healthy with uncomplicated pregnancies at time of enrollment\n* Non-pregnant subjects (18-35 yrs): healthy, non-smoking, not taking vitamin or mineral supplements and not planning on becoming pregnant during course of study.\n\nExclusion Criteria:\n\n* Pregnant subjects: gestational diabetes, hypertension, preeclampsia, underlying malabsorption diseases or other diagnosed medical problems known to impact iron homeostasis\n* Non-pregnant subjects: underlying malabsorption diseases or other diagnosed medical problems known to impact iron homeostasis.",true,"FEMALE","15 Years","35 Years",{"count":50,"type":51},55,"ACTUAL","OBSERVATIONAL","The three specific aims of this study are 1) to assess the impact of iron status on relative differences in absorption of heme and non-heme iron among pregnant women and non-pregnant women, 2) to assess the magnitude and the determinants of heme and non-heme iron transfer to the fetus over the last trimester of pregnancy, and 3) to characterize relationships between placental iron binding proteins with the enrichment of stable iron isotopes in the neonate at birth. The investigators hypothesize that there will be up regulation of heme and non-heme iron absorption and up regulation of placental iron transport proteins in response to low maternal iron stores.",[55],"Iron Deficiency",[57,58,59,60,61,62],"iron","pregnancy","heme iron","non-heme iron","stable isotopes","women\u002Fadolescents","COMPLETED","2012-03-21",{"date":66,"type":67},"2012-03-22","ESTIMATED",{"date":69,"type":7},"2008-05",{"date":71,"type":51},"2011-07",{"name":5,"class":6},2]