[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100241759":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":25,"centralContacts":34,"locations":44,"responsibleParty":64,"collaborators":66,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":10,"enrollmentInfo":80,"targetDuration":10,"studyType":83,"phases":10,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":93,"whyStopped":10,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Isis-Virus",null,"T1D patients of the Isis-Diab cohort with genetic data (GWAS) and specific environmental data on viral events during childhood",[13,14],"Other: Collect of data on viral environment of T1D patients","Genetic: Collect of blood samples for DNA extraction and genetic characterization (GWAS)",[16,20],{"type":6,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"Collect of data on viral environment of T1D patients","Questionnaires on viral events during mother's pregnancy and patient's childhood, health book copies, addresses' geolocation, quantification of viral exposures using Sentinel Network data",[9],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"GENETIC","Collect of blood samples for DNA extraction and genetic characterization (GWAS)","Collect of blood samples for DNA extraction and genetic characterization (GWAS) on Illumina platform (Centre National de Genotypage)",[9],[26,30],{"name":27,"affiliation":28,"role":29},"Alain-Jacques Valleron, PhD","Institut National de la Santé Et de la Recherche Médicale, France","PRINCIPAL_INVESTIGATOR",{"name":31,"affiliation":32,"role":33},"Pierre Bougnères, MD, PhD","Inserm U986 \u002F Pediatric endocrinology department of the Bicêtre Hospital (AP-HP)","STUDY_DIRECTOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},"Sophie Le Fur, PhD","CONTACT","+33 1 49 59 53 43","sophie.le-fur@inserm.fr",{"name":41,"role":37,"phone":42,"phoneExt":10,"email":43},"Laurence LECOMTE, PhD","+ 33 1 71 19 64 94","laurence.lecomte@nck.aphp.fr",[45],{"facility":46,"status":47,"city":48,"state":10,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Inserm U986","RECRUITING","Le Kremlin-Bicêtre","94276","France","FR",{"type":53,"coordinates":54},"Point",[55,56],2.36073,48.81471,{"lat":56,"lon":55},[59,61],{"name":36,"role":37,"phone":60,"phoneExt":10,"email":39},"+ 33 1 49 59 53 43",{"name":62,"role":37,"phone":63,"phoneExt":10,"email":43},"Laurence Lecomte, PhD","+33 1 71 19 64 94",{"type":65,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[67,69],{"name":68,"class":6},"Centre National de Génotypage",{"name":28,"class":70},"OTHER_GOV","100241759","analysis-of-viral-infections-exposition-preceding-the-type-1-diabetes-t1d-diagnostic-in-children-of-the-isis-diab-cohort-search-for-explanations-of-of-the-diseases-early-onset-100241759",false,"NCT02425410","Analysis of Viral Infections' Exposition Preceding the Type 1 Diabetes (T1D) Diagnostic in Children of the Isis-Diab Cohort. Search for Explanations of of the Disease's Early Onset","ISIS-VIRUS","Inclusion Criteria:\n\n* Type 1 diabetic patients included in the Isis-Diab cohort\n* Patients with available genetic data (GWAS)\n\nExclusion Criteria:\n\n* Patient refusal (or parents) to participate in the study.","ALL","6 Months",{"count":81,"type":82},2000,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to investigate viral factors determining the early onset of T1D. Thanks to the quantification of viral exposures of T1D patients before the disease onset with questionnaires and environmental databases analyses, and through whole genome association studies of these patients, investigators could attempt to identify gene-virus interactions determining the age of T1D onset.",[86,87],"Diabetes Mellitus","Insulin-Dependent",[86,87,89,90,91,92],"Virus Diseases","Questionnaires","Risk assessment","Genome-Wide Association Study","UNKNOWN","2016-06-27",{"date":96,"type":82},"2016-06-28",{"date":98,"type":10},"2010-03",{"date":100,"type":82},"2018-06",{"name":5,"class":6},1]