[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100259343":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":23,"locations":32,"responsibleParty":45,"collaborators":23,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":49,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":23,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":70,"whyStopped":71,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University Hospital, Lille","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Bone Marrow +BMP7","EXPERIMENTAL","The drilling is completed by a joint supply of autologous marrow unconcentrated and recombinant BMP7 (OP1)",[13],"Biological: Bone Marrow +BMP7",{"label":15,"type":16,"description":17,"interventionNames":18},"Drilling","PLACEBO_COMPARATOR","Group I: a simple drill is practiced",[19],"Procedure: Drilling",[21,25],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":23},"PROCEDURE",null,[15],{"type":26,"name":9,"description":23,"armGroupLabels":27,"otherNames":23},"BIOLOGICAL",[9],[29],{"name":30,"affiliation":5,"role":31},"Henri Migaud, MD, PhD","STUDY_CHAIR",[33],{"facility":34,"status":23,"city":35,"state":23,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":23},"CHRU de LILLE - service d'orthopédie C","Lille","59037","France","FR",{"type":40,"coordinates":41},"Point",[42,43],3.05512,50.63391,{"lat":43,"lon":42},{"type":46,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100259343","autologous-bone-marrow-and-bmp7-treatment-in-the-necrosis-in-the-femoral-head-of-the-adult-100259343",false,"NCT02655120","Autologous Bone Marrow and BMP7 Treatment in the Necrosis in the Femoral Head of the Adult","Evaluation of the Efficiency of Autologous Bone Marrow no Concentrated to Associate at BMP7 Treatment of Necrosis of the Femoral Head of the Adult","BMP7","Inclusion Criteria:\n\n* Patient aged between 18 and 60 years male or female.\n* Necrosis of the femoral head stage I to III FICAT (stage III with depression of less than 3 mm)\n* Nontraumatic osteonecrosis\n* Patient can undergo general anesthesia or locoregional\n* Having given his consent\n* Able to understand the constraints of the study\n\nExclusion Criteria:\n\n* Refusing to participate in the study\n* Active infection at the site\n* Cancer changing\n* Pregnancy\n* Necrosis posttraumatic\n* Having already undergone surgery on the surgical site\n* Contraindication to the practice of NMRI\n* Contraindication to the use of OP1 (BMP7): collagen, arthritis, scleroderma, lupus\n* Patient participating in another ongoing study","ALL","18 Years","60 Years",{"count":59,"type":60},41,"ACTUAL","INTERVENTIONAL",[63],"NA","The main objective of the study is to evaluate the effectiveness of the injection of bone marrow unconcentrated more R BMP 7 to repair necrosis of the femoral head with stage I-III classification FICAT.",[66],"Aseptic Necrosis of Femur Head",[68,69,53],"Femoral head necrosis","Autologous Bone Marrow","TERMINATED","stopping the marketing of BMP7","2018-05-02",{"date":74,"type":60},"2018-05-08",{"date":76,"type":23},"2005-03",{"date":78,"type":60},"2017-05",{"name":5,"class":6},1]