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Carbone Comprehensive Cancer Center","Madison","53792-6164",{"type":33,"coordinates":2487},[2488,2489],-89.40123,43.07305,{"lat":2489,"lon":2488},{"facility":2492,"status":10,"city":2493,"state":2432,"zip":2494,"country":30,"countryCode":31,"cosmosGeoPoint":2495,"geoPoint":2499,"contacts":10},"Bay Area Cancer Care Center at Bay Area Medical Center","Marinette","54143",{"type":33,"coordinates":2496},[2497,2498],-87.63066,45.09998,{"lat":2498,"lon":2497},{"facility":2501,"status":10,"city":2502,"state":2432,"zip":2503,"country":30,"countryCode":31,"cosmosGeoPoint":2504,"geoPoint":2508,"contacts":10},"Aurora Sinai Medical Center","Milwaukee","53201-0342",{"type":33,"coordinates":2505},[2506,2507],-87.90647,43.0389,{"lat":2507,"lon":2506},{"facility":2510,"status":10,"city":2502,"state":2432,"zip":2511,"country":30,"countryCode":31,"cosmosGeoPoint":2512,"geoPoint":2514,"contacts":10},"Medical Consultants, Limited","53215",{"type":33,"coordinates":2513},[2506,2507],{"lat":2507,"lon":2506},{"facility":2516,"status":10,"city":2517,"state":2432,"zip":2518,"country":30,"countryCode":31,"cosmosGeoPoint":2519,"geoPoint":2523,"contacts":10},"Green Bay Oncology, Limited - Oconto Falls","Oconto Falls","54154",{"type":33,"coordinates":2520},[2521,2522],-88.14288,44.87388,{"lat":2522,"lon":2521},{"facility":2525,"status":10,"city":2526,"state":2432,"zip":2527,"country":30,"countryCode":31,"cosmosGeoPoint":2528,"geoPoint":2532,"contacts":10},"All Saints Cancer Center at Wheaton Franciscan Healthcare","Racine","53405",{"type":33,"coordinates":2529},[2530,2531],-87.78285,42.72613,{"lat":2531,"lon":2530},{"facility":2534,"status":10,"city":2535,"state":2432,"zip":2536,"country":30,"countryCode":31,"cosmosGeoPoint":2537,"geoPoint":2541,"contacts":10},"Green Bay Oncology, Limited - Sturgeon Bay","Sturgeon Bay","54235",{"type":33,"coordinates":2538},[2539,2540],-87.37704,44.83416,{"lat":2540,"lon":2539},{"facility":2543,"status":10,"city":2544,"state":2432,"zip":2545,"country":30,"countryCode":31,"cosmosGeoPoint":2546,"geoPoint":2550,"contacts":10},"University of Wisconcin Cancer Center at Aspirus Wausau Hospital","Wausau","54401",{"type":33,"coordinates":2547},[2548,2549],-89.63012,44.95914,{"lat":2549,"lon":2548},{"facility":2552,"status":10,"city":2553,"state":2554,"zip":2555,"country":30,"countryCode":31,"cosmosGeoPoint":2556,"geoPoint":2560,"contacts":10},"Welch Cancer Center at Sheridan Memorial Hospital","Sheridan","Wyoming","82801",{"type":33,"coordinates":2557},[2558,2559],-106.95618,44.79719,{"lat":2559,"lon":2558},{"facility":2562,"status":10,"city":2563,"state":2564,"zip":2565,"country":2566,"countryCode":2567,"cosmosGeoPoint":2568,"geoPoint":2572,"contacts":10},"British Columbia Cancer Agency - Vancouver Cancer Centre","Vancouver","British Columbia","V5Z 4E6","Canada","CA",{"type":33,"coordinates":2569},[2570,2571],-123.11934,49.24966,{"lat":2571,"lon":2570},{"facility":2574,"status":10,"city":2575,"state":2576,"zip":2577,"country":2566,"countryCode":2567,"cosmosGeoPoint":2578,"geoPoint":2582,"contacts":10},"CancerCare Manitoba","Winnipeg","Manitoba","R3E 0V9",{"type":33,"coordinates":2579},[2580,2581],-97.14704,49.8844,{"lat":2581,"lon":2580},{"facility":2584,"status":10,"city":2585,"state":2586,"zip":2587,"country":2566,"countryCode":2567,"cosmosGeoPoint":2588,"geoPoint":2592,"contacts":10},"Moncton Hospital","Moncton","New Brunswick","E1C 6Z8",{"type":33,"coordinates":2589},[2590,2591],-64.7965,46.09454,{"lat":2591,"lon":2590},{"facility":2594,"status":10,"city":2595,"state":2586,"zip":2596,"country":2566,"countryCode":2567,"cosmosGeoPoint":2597,"geoPoint":2601,"contacts":10},"Saint John Regional Hospital","Saint John","E2L 4L2",{"type":33,"coordinates":2598},[2599,2600],-66.05616,45.27076,{"lat":2600,"lon":2599},{"facility":2603,"status":10,"city":2604,"state":2605,"zip":2606,"country":2566,"countryCode":2567,"cosmosGeoPoint":2607,"geoPoint":2611,"contacts":10},"Cambridge Memorial Hospital","Cambridge","Ontario","N1R 3G2",{"type":33,"coordinates":2608},[2609,2610],-80.31269,43.3601,{"lat":2610,"lon":2609},{"facility":2613,"status":10,"city":2614,"state":2605,"zip":2615,"country":2566,"countryCode":2567,"cosmosGeoPoint":2616,"geoPoint":2620,"contacts":10},"Algoma District Cancer Program at Sault Area Hospital","Sault Ste. Marie","P6A 2C4",{"type":33,"coordinates":2617},[2618,2619],-84.33325,46.51677,{"lat":2619,"lon":2618},{"facility":2622,"status":10,"city":2623,"state":2605,"zip":2624,"country":2566,"countryCode":2567,"cosmosGeoPoint":2625,"geoPoint":2629,"contacts":10},"Cancer Care Program at Thunder Bay Regional Health Sciences","Thunder Bay","P7B 6V4",{"type":33,"coordinates":2626},[2627,2628],-89.25018,48.38202,{"lat":2628,"lon":2627},{"facility":2631,"status":10,"city":2632,"state":2605,"zip":2633,"country":2566,"countryCode":2567,"cosmosGeoPoint":2634,"geoPoint":2638,"contacts":10},"Edmond Odette Cancer Centre at Sunnybrook","Toronto","M4N 3M5",{"type":33,"coordinates":2635},[2636,2637],-79.39864,43.70643,{"lat":2637,"lon":2636},{"facility":2640,"status":10,"city":2632,"state":2605,"zip":2641,"country":2566,"countryCode":2567,"cosmosGeoPoint":2642,"geoPoint":2644,"contacts":10},"St. Michael's Hospital - Toronto","M5B 1W8",{"type":33,"coordinates":2643},[2636,2637],{"lat":2637,"lon":2636},{"facility":2646,"status":10,"city":2632,"state":2605,"zip":2647,"country":2566,"countryCode":2567,"cosmosGeoPoint":2648,"geoPoint":2650,"contacts":10},"Princess Margaret Hospital","M5G 2M9",{"type":33,"coordinates":2649},[2636,2637],{"lat":2637,"lon":2636},{"facility":2652,"status":10,"city":2653,"state":2654,"zip":2655,"country":2566,"countryCode":2567,"cosmosGeoPoint":2656,"geoPoint":2660,"contacts":10},"Hopital Charles Lemoyne","Greenfield Park","Quebec","J4V 2H1",{"type":33,"coordinates":2657},[2658,2659],-73.46223,45.48649,{"lat":2659,"lon":2658},{"facility":2662,"status":10,"city":2663,"state":2654,"zip":2664,"country":2566,"countryCode":2567,"cosmosGeoPoint":2665,"geoPoint":2669,"contacts":10},"Hopital du Saint-Sacrement - Quebec","Québec","G1S 4L8",{"type":33,"coordinates":2666},[2667,2668],-71.21454,46.81228,{"lat":2668,"lon":2667},{"facility":2671,"status":10,"city":2672,"state":2673,"zip":2674,"country":2566,"countryCode":2567,"cosmosGeoPoint":2675,"geoPoint":2679,"contacts":10},"Allan Blair Cancer Centre at Pasqua Hospital","Regina","Saskatchewan","S4T 7T1",{"type":33,"coordinates":2676},[2677,2678],-104.6178,50.45008,{"lat":2678,"lon":2677},{"type":2681,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[2683,2686],{"name":2684,"class":2685},"National Cancer Institute (NCI)","NIH",{"name":2687,"class":2688},"NCIC Clinical Trials Group","NETWORK","100081459","breast-density-hormone-levels-and-anticancer-drug-levels-in-women-with-invasive-breast-cancer-who-are-receiving-exemestane-or-anastrozole-100081459",false,"NCT00316836","Breast Density, Hormone Levels, and Anticancer Drug Levels in Women With Invasive Breast Cancer Who Are Receiving Exemestane or Anastrozole","The Association of Breast Density Changes, Plasma Hormone Changes, and Breast Cancer Recurrence: A Companion Study to NCIC CTG MA.27","DISEASE CHARACTERISTICS:\n\n* Histologically confirmed invasive breast cancer\n* Completely resected disease\n* One intact, noncancerous breast with no prior breast surgery in that breast except breast biopsy\n\n  * Mammogram available taken within 12 months prior to enrollment that includes side- and top-down views of the intact, noncancerous breast\n* Estrogen receptor- and\u002For progesterone receptor-positive tumor\n\nPATIENT CHARACTERISTICS:\n\n* Female\n* Postmenopausal\n* Agrees to retrieve and digitize mammograms taken prior to registration (within 12 months prior to atudy entry) and at approximately 1 and 2 years post-registration to this study\n* Agrees to have an additional blood banking specimen drawn at the same time as pre-treatment specimens are drawn for parent protocol CAN-NCIC-MA27\n* Agrees to have blood sample taken at 12 months post-registration on this study\n\nPRIOR CONCURRENT THERAPY:\n\n* See Disease Characteristics\n* More than 6 months since prior hormone replacement therapy, oral contraceptives, tamoxifen, raloxifene, other selective estrogen-receptor modulators, or gonadotropin releasing-hormone analogues before pre-registration mammogram","FEMALE","18 Years",{"count":2699,"type":2700},554,"ACTUAL","OBSERVATIONAL","RATIONALE: Understanding the relationship between breast density, levels of hormones in the blood, and levels of anticancer drugs in the blood may help improve the ability to plan effective treatment for women with invasive breast cancer.\n\nPURPOSE: This clinical trial is studying the relationship between breast density and blood levels of hormones and anticancer drugs in women with invasive breast cancer who are receiving exemestane or anastrozole.",[2704],"Breast Cancer",[2706,2707,2708],"stage I breast cancer","stage II breast cancer","stage IIIA breast cancer","COMPLETED","2019-01-22",{"date":2712,"type":2700},"2019-01-24",{"date":2714,"type":10},"2006-04",{"date":2716,"type":2700},"2012-02",{"name":5,"class":6},324]