[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100487969":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":13,"locations":23,"responsibleParty":48,"collaborators":7,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":7,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":63,"studyType":64,"phases":7,"briefSummary":65,"conditions":66,"keywords":70,"overallStatus":74,"whyStopped":7,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Meshalkin Research Institute of Pathology of Circulation","NETWORK",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","aneurysmectomy with sampling of a segment of the aneurysm wall","Patients with aneurysms of the abdominal aorta undergo an ultrasound examination of the abdominal aorta to assess the elastic properties of the aortic wall. The accessible wall of the abdominal aortic aneurysm is taken intraoperatively.\n\nIn in vitro studies, the strength properties of the aneurysm wall are measured during uniaxial tension on a tensile testing machine, which makes it possible to evaluate the elastic properties of the test sample.\n\nThe assessment of the boundaries of the linearity of the surface under study, as well as the yield strength of the vascular wall and thrombotic masses, is evaluated under shear stresses using a rheometer. To correlate the mechanical properties with the structural composition of the aneurysm tissue, spectral analysis of the studied tissues by laser-induced fluorescence and histological examination with staining of the obtained sections for the presence of elastic fibers, fibrous tissues and calcification will be used.",[14,19],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Andrey A Karpenko, PhD","CONTACT","+79139504100","andreikarpenko@rambler.ru",{"name":20,"role":16,"phone":21,"phoneExt":7,"email":22},"Alexandr A Gostev, PhD","+79139555074","a_gostev@meshalkin.ru",[24,37,43],{"facility":25,"status":7,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":7},"Alexander A Gostev","Novosibirsk","Novosibirskaya Obl","630005","Russia","RU",{"type":32,"coordinates":33},"Point",[34,35],82.93175,55.02259,{"lat":35,"lon":34},{"facility":38,"status":7,"city":26,"state":7,"zip":39,"country":29,"countryCode":30,"cosmosGeoPoint":40,"geoPoint":42,"contacts":7},"Federal State Institution Academician E.N.Meshalkin Novosibirsk State Research Institute Of Circulation Pathology Rusmedtechnology","630055",{"type":32,"coordinates":41},[34,35],{"lat":35,"lon":34},{"facility":44,"status":7,"city":26,"state":7,"zip":7,"country":29,"countryCode":30,"cosmosGeoPoint":45,"geoPoint":47,"contacts":7},"E. Meshalkin National Medical Research Center",{"type":32,"coordinates":46},[34,35],{"lat":35,"lon":34},{"type":49,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100487969","comparison-of-the-biomechanical-properties-of-the-wall-of-an-aneurysmal-altered-abdominal-aorta-according-to-the-results-of-in-vivo-ultrasound-and-an-associated-study-of-strength-characteristics-in-vitro-100487969",false,"NCT05634018","Comparison of the Biomechanical Properties of the Wall of an Aneurysmal-altered Abdominal Aorta According to the Results of in Vivo Ultrasound and an Associated Study of Strength Characteristics in Vitro","Prospective Assessment of the Biomechanical Properties of the Wall of an Aneurysmal-altered Abdominal Aorta According to the Results of in Vivo Ultrasound and an Associated Study of Strength Characteristics in Vitro","Inclusion Criteria:\n\n* Patients with an aneurysmal expansion of the abdominal aorta who are indicated for surgery.\n* Patients who consented to participate in this study\n\nExclusion Criteria:\n\n* Chronic heart failure III-IV functional class according to the NYHA classification;\n* Chronic decompensated \"pulmonary\" heart;\n* Severe hepatic or renal insufficiency (bilirubin \\> 35 mmol \u002F l, glomerular filtration rate \\\u003C 60 ml \u002F min);\n* Polyvalent drug allergy;\n* Malignant oncological diseases in the terminal stage with a predicted lifespan of up to 6 months;\n* Acute violation of cerebral circulation;","ALL","45 Years","75 Years",{"count":61,"type":62},50,"ESTIMATED","1 Month","OBSERVATIONAL","Identification of the regression model between the strength properties of tissue and its ultrasonic spectral characteristics.",[67,68,69],"the Strength Properties of the Aorta in Vivo","the Strength Properties of the Aorta in Vitro","Regression Model of Aortic Strength Properties in Vitro and in Vitro",[71,72,73],"aneurysm wall strength","speckle tracking","shear yield strength","UNKNOWN","2022-12-13",{"date":77,"type":78},"2022-12-14","ACTUAL",{"date":80,"type":62},"2023-01-01",{"date":82,"type":62},"2023-04-30",{"name":5,"class":6},3]