[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626297":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":53,"collaborators":26,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":26,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":26,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":80,"whyStopped":26,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Soma State Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"iPACK Block","ACTIVE_COMPARATOR","At the end of surgery, all patients will receive an adductor canal block in the recovery unit under sterile conditions and ultrasound guidance using 10 mL of 0.25% bupivacaine. In addition, in the iPACK block group, the patient will be positioned in the lateral decubitus position, and under sterile conditions, a linear ultrasound probe will be used to advance a 22G, 100-mm block needle to the space between the popliteal artery and the posterior capsule of the knee. After negative aspiration, an iPACK block will be performed with 25 mL of 0.25% bupivacaine.",[13],"Procedure: IPACK block",{"label":15,"type":16,"description":17,"interventionNames":18},"BiFeS Block","OTHER","At the end of surgery, all patients will receive an adductor canal block in the recovery unit under sterile conditions and ultrasound guidance using 10 mL of 0.25% bupivacaine. In addition, in the BiFeS block group, with the patient in the supine position and under sterile conditions, a linear ultrasound probe will be used, and a 22G, 100-mm block needle will be advanced to the space between the short head of the biceps femoris muscle and the lateral epicondyle of the femur. After negative aspiration, the BiFeS block will be performed using 25 mL of 0.25% bupivacaine.",[19],"Procedure: BiFeS Block",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","IPACK block","Unilateral iPACK block with 25 mL of mixture 1:1 (0.5 % bupivacaine: 0.9% NaCl)",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Unilateral BiFeS block with 25 mL of mixture 1:1 (0.5 % bupivacaine: 0.9% NaCl)",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Meltem Savas Ozdemir, MD","CONTACT","+905557331143","drmeltemsavas@gmail.com",[37],{"facility":5,"status":26,"city":38,"state":39,"zip":40,"country":41,"countryCode":26,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Manisa","Soma","45500","Turkey (Türkiye)",{"type":43,"coordinates":44},"Point",[45,46],27.42647,38.61202,{"lat":46,"lon":45},[49,50],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},{"name":51,"role":52,"phone":26,"phoneExt":26,"email":26},"Pelin Dilsiz Eker, MD","SUB_INVESTIGATOR",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Meltem Savas Ozdemir","MD., specialist","100626297","comparison-of-the-postoperative-analgesic-efficacy-of-infiltration-between-the-popliteal-artery-and-the-capsule-of-the-knee-ipack-block-and-the-biceps-femoris-short-head-plane-bifes-block-in-total-knee-arthroplasty-100626297",false,"NCT07433803","Comparison of the Postoperative Analgesic Efficacy of Infiltration Between the Popliteal Artery and the Capsule of the Knee (iPACK) Block and the Biceps Femoris Short Head Plane (BiFeS) Block in Total Knee Arthroplasty","Comparison of the Postoperative Analgesic Efficacy of Infiltration Between the Popliteal Artery and the Capsule of the Knee (iPACK) Block and the Biceps Femoris Short Head Plane (BiFeS) Block in Total Knee Arthroplasty: A Prospective, Randomized, Double-Blind, Non-Inferiority Trial","Inclusion Criteria:\n\n* Patients scheduled for unilateral total knee arthroplasty\n* Patients aged between 18 and 75 years\n* Patients with ASA physical status I-III\n\nExclusion Criteria:\n\n* Patients with neuropsychiatric disorders\n* Patients with obesity (BMI \\> 30)\n* Presence of local infection at the site where the block will be performed\n* Patients with coagulation disorders\n* Patients with uncontrolled diabetes mellitus\n* Opioid dependence\n* History of allergy to local anesthetic agents\n* Refusal to participate in the study","ALL","18 Years","75 Years",{"count":68,"type":69},100,"ESTIMATED","INTERVENTIONAL",[72],"NA","This study aims to compare the effects of two regional analgesia techniques applied in patients undergoing unilateral total knee arthroplasty-Infiltration between the Popliteal Artery and the Capsule of the Knee (iPACK) block and the Biceps Femoris Short Head Plane (BiFeS) block-on ease of application, postoperative pain scores, time to mobilization, total postoperative opioid consumption, need for first rescue analgesia, and the incidence of nausea-vomiting and pruritus.All patients will be followed postoperatively according to a standard pain management protocol, and pain assessments will be performed at predetermined time intervals using the VAS (Visual Analog Scale).",[75],"Postoperative Pain",[15,9,77,78,79],"Postoperative pain scores","Time to mobilization","Total opioid consumption","NOT_YET_RECRUITING","2026-04-28",{"date":83,"type":84},"2026-05-04","ACTUAL",{"date":86,"type":69},"2026-05-15",{"date":88,"type":69},"2026-09-16",{"name":5,"class":6},1]