[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100055610":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":24,"centralContacts":10,"locations":29,"responsibleParty":540,"collaborators":542,"id":549,"slug":550,"hasResults":551,"nctId":552,"briefTitle":553,"officialTitle":554,"acronym":10,"eligibilityCriteria":555,"healthyVolunteers":551,"sex":556,"minAge":557,"maxAge":558,"enrollmentInfo":559,"targetDuration":10,"studyType":562,"phases":10,"briefSummary":563,"conditions":564,"keywords":567,"overallStatus":571,"whyStopped":10,"lastUpdateSubmitDate":572,"lastUpdatePostDateStruct":573,"startDateStruct":576,"completionDateStruct":578,"leadSponsor":580,"locationsCount":581},{"fullName":5,"class":6},"Alliance for Clinical Trials in Oncology","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patient interviewing + blood sampling",null,"Patients were interviewed at the time of the primary cancer surgery to determine the menstrual history. Blood sampling occurred within 1 day of surgery, and serum samples were shipped frozen to a central laboratory (Mayo Medical Laboratory, Rochester, MN) for E2, Pg, and LH determinations. Serum hormone levels, menstrual cycle length, and day of last menses were used to determine the menstrual phase at which surgery occurred.\n\nPatients were observed every 6 months for the first year postregistration and annually for the next 2 to 10 years postregistration for adjuvant therapy information, disease recurrence, and death.",[13,14],"Behavioral: patient interviewing to obtain menstrual history","Procedure: blood sampling",[16,20],{"type":17,"name":18,"description":10,"armGroupLabels":19,"otherNames":10},"BEHAVIORAL","patient interviewing to obtain menstrual history",[9],{"type":21,"name":22,"description":10,"armGroupLabels":23,"otherNames":10},"PROCEDURE","blood sampling",[9],[25],{"name":26,"affiliation":27,"role":28},"Clive S. 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Syracuse Hematology-Oncology Associates of Central New York, P.C.","Syracuse","New York","13217",{"type":38,"coordinates":305},[306,307],-76.14742,43.04812,{"lat":307,"lon":306},{"facility":310,"status":10,"city":311,"state":312,"zip":313,"country":35,"countryCode":36,"cosmosGeoPoint":314,"geoPoint":318,"contacts":10},"CCOP - Southeast Cancer Control Consortium","Winston-Salem","North Carolina","27104-4241",{"type":38,"coordinates":315},[316,317],-80.24422,36.09986,{"lat":317,"lon":316},{"facility":320,"status":10,"city":311,"state":312,"zip":321,"country":35,"countryCode":36,"cosmosGeoPoint":322,"geoPoint":324,"contacts":10},"Comprehensive Cancer Center at Wake Forest University","27157-1082",{"type":38,"coordinates":323},[316,317],{"lat":317,"lon":316},{"facility":326,"status":10,"city":327,"state":328,"zip":329,"country":35,"countryCode":36,"cosmosGeoPoint":330,"geoPoint":334,"contacts":10},"Akron City Hospital","Akron","Ohio","44309-2090",{"type":38,"coordinates":331},[332,333],-81.51901,41.08144,{"lat":333,"lon":332},{"facility":336,"status":10,"city":337,"state":328,"zip":338,"country":35,"countryCode":36,"cosmosGeoPoint":339,"geoPoint":343,"contacts":10},"Aultman Hospital Cancer Center at Aultman Health Foundation","Canton","44710-1799",{"type":38,"coordinates":340},[341,342],-81.37845,40.79895,{"lat":342,"lon":341},{"facility":345,"status":10,"city":346,"state":328,"zip":347,"country":35,"countryCode":36,"cosmosGeoPoint":348,"geoPoint":352,"contacts":10},"Charles M. Barrett Cancer Center at University Hospital","Cincinnati","45219-0502",{"type":38,"coordinates":349},[350,351],-84.51439,39.12711,{"lat":351,"lon":350},{"facility":354,"status":10,"city":355,"state":328,"zip":356,"country":35,"countryCode":36,"cosmosGeoPoint":357,"geoPoint":361,"contacts":10},"South Pointe Hospital","Cleveland","44122",{"type":38,"coordinates":358},[359,360],-81.69541,41.4995,{"lat":360,"lon":359},{"facility":363,"status":10,"city":364,"state":328,"zip":365,"country":35,"countryCode":36,"cosmosGeoPoint":366,"geoPoint":370,"contacts":10},"CCOP - Columbus","Columbus","43206",{"type":38,"coordinates":367},[368,369],-82.99879,39.96118,{"lat":369,"lon":368},{"facility":372,"status":10,"city":373,"state":328,"zip":374,"country":35,"countryCode":36,"cosmosGeoPoint":375,"geoPoint":379,"contacts":10},"CCOP - Dayton","Dayton","45429",{"type":38,"coordinates":376},[377,378],-84.19161,39.75895,{"lat":378,"lon":377},{"facility":381,"status":10,"city":382,"state":383,"zip":384,"country":35,"countryCode":36,"cosmosGeoPoint":385,"geoPoint":389,"contacts":10},"CCOP - Oklahoma","Tulsa","Oklahoma","74136",{"type":38,"coordinates":386},[387,388],-95.99277,36.15398,{"lat":388,"lon":387},{"facility":391,"status":10,"city":392,"state":393,"zip":394,"country":35,"countryCode":36,"cosmosGeoPoint":395,"geoPoint":399,"contacts":10},"St. Luke's Hospital and Health Network - Bethlehem","Bethlehem","Pennsylvania","18015",{"type":38,"coordinates":396},[397,398],-75.37046,40.62593,{"lat":398,"lon":397},{"facility":401,"status":10,"city":402,"state":393,"zip":403,"country":35,"countryCode":36,"cosmosGeoPoint":404,"geoPoint":408,"contacts":10},"Allegheny General Hospital","Pittsburgh","15212-4772",{"type":38,"coordinates":405},[406,407],-79.99589,40.44062,{"lat":407,"lon":406},{"facility":410,"status":10,"city":402,"state":393,"zip":411,"country":35,"countryCode":36,"cosmosGeoPoint":412,"geoPoint":414,"contacts":10},"Hillman Cancer Center at University of Pittsburgh Cancer Institute","15236",{"type":38,"coordinates":413},[406,407],{"lat":407,"lon":406},{"facility":416,"status":10,"city":417,"state":393,"zip":418,"country":35,"countryCode":36,"cosmosGeoPoint":419,"geoPoint":423,"contacts":10},"CCOP - MainLine Health","Wynnewood","19096",{"type":38,"coordinates":420},[421,422],-75.27074,40.00289,{"lat":422,"lon":421},{"facility":425,"status":10,"city":426,"state":393,"zip":427,"country":35,"countryCode":36,"cosmosGeoPoint":428,"geoPoint":432,"contacts":10},"Wellspan Health - York Cancer Center","York","17403",{"type":38,"coordinates":429},[430,431],-76.72774,39.9626,{"lat":431,"lon":430},{"facility":434,"status":10,"city":435,"state":436,"zip":437,"country":35,"countryCode":36,"cosmosGeoPoint":438,"geoPoint":442,"contacts":10},"Kent County Memorial Hospital","Warwick","Rhode Island","02886",{"type":38,"coordinates":439},[440,441],-71.41617,41.7001,{"lat":441,"lon":440},{"facility":444,"status":10,"city":445,"state":446,"zip":447,"country":35,"countryCode":36,"cosmosGeoPoint":448,"geoPoint":452,"contacts":10},"CCOP - Upstate Carolina","Spartanburg","South Carolina","29303",{"type":38,"coordinates":449},[450,451],-81.93205,34.94957,{"lat":451,"lon":450},{"facility":454,"status":10,"city":455,"state":456,"zip":457,"country":35,"countryCode":36,"cosmosGeoPoint":458,"geoPoint":462,"contacts":10},"CCOP - Sioux Community Cancer Consortium","Sioux Falls","South Dakota","57104",{"type":38,"coordinates":459},[460,461],-96.72796,43.54369,{"lat":461,"lon":460},{"facility":464,"status":10,"city":465,"state":466,"zip":467,"country":35,"countryCode":36,"cosmosGeoPoint":468,"geoPoint":472,"contacts":10},"Eastern Virginia Medical School","Norfolk","Virginia","23507",{"type":38,"coordinates":469},[470,471],-76.28522,36.84681,{"lat":471,"lon":470},{"facility":474,"status":10,"city":475,"state":476,"zip":477,"country":35,"countryCode":36,"cosmosGeoPoint":478,"geoPoint":482,"contacts":10},"CCOP - Virginia Mason Research Center","Seattle","Washington","98101",{"type":38,"coordinates":479},[480,481],-122.33207,47.60621,{"lat":481,"lon":480},{"facility":484,"status":10,"city":475,"state":476,"zip":485,"country":35,"countryCode":36,"cosmosGeoPoint":486,"geoPoint":488,"contacts":10},"Puget Sound Oncology Consortium","98109",{"type":38,"coordinates":487},[480,481],{"lat":481,"lon":480},{"facility":490,"status":10,"city":491,"state":476,"zip":492,"country":35,"countryCode":36,"cosmosGeoPoint":493,"geoPoint":497,"contacts":10},"CCOP - 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Montreal","Montreal","Quebec","H3T 1E2",{"type":38,"coordinates":536},[537,538],-73.58781,45.50884,{"lat":538,"lon":537},{"type":541,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[543,546],{"name":544,"class":545},"National Cancer Institute (NCI)","NIH",{"name":547,"class":548},"NSABP Foundation Inc","NETWORK","100055610","correlation-of-menstrual-cycle-phase-at-time-of-primary-surgery-with-5-year-disease-free-survival-in-women-with-stage-i-or-stage-ii-breast-cancer-100055610",false,"NCT00002762","Correlation of Menstrual Cycle Phase at Time of Primary Surgery With 5-Year Disease-Free Survival in Women With Stage I or Stage II Breast Cancer","MENSTRUAL CYCLE AND SURGICAL TREATMENT OF BREAST CANCER","Inclusion Criteria:\n\n1. Women age 18 to 55 years\n2. Regular menstrual cycles of 21- to 35-days duration\n3. Pathologic stages I to II breast cancer, in whom all gross disease-including ductal carcinoma in situ-was surgically removed either in a one-stage or two-stage procedure.\n4. required serum be drawn within 1 calendar day of the lumpectomy\u002Fmastectomy for women who underwent a one-stage procedure and within 1 calendar day of each stage for women who underwent a two-stage procedure.\n\nExclusion Criteria:\n\n1. Lactation within the past 3 months\n2. galactorrhea\n3. neoadjuvant therapy\n4. previous breast cancer, and history of any cancer (except squamous or basal cell skin carcinoma) in which the patient was not disease-free for at least 10 years","FEMALE","18 Years","55 Years",{"count":560,"type":561},1118,"ACTUAL","OBSERVATIONAL","RATIONALE: Timing of breast cancer surgery may improve effectiveness of treatment and may help patients live longer.\n\nPURPOSE: Clinical trial to determine whether timing of primary surgery in relation to menstrual cycle is associated with disease-free survival 5 years after surgery in women who have stage I or stage II breast cancer.",[565,566],"Breast Cancer","Perioperative\u002FPostoperative Complications",[568,569,570],"stage I breast cancer","stage II breast cancer","perioperative\u002Fpostoperative complications","COMPLETED","2016-07-11",{"date":574,"type":575},"2016-07-12","ESTIMATED",{"date":577,"type":10},"1996-06",{"date":579,"type":561},"2009-10",{"name":5,"class":6},54]