[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100191527":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":18,"locations":24,"responsibleParty":37,"collaborators":18,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":43,"sex":49,"minAge":50,"maxAge":18,"enrollmentInfo":51,"targetDuration":18,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":63,"whyStopped":18,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de Besancon","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Echocardiography","An echocardiography will be systematically realised in all the patients included in the study in order to evaluate whether any echocardiographic criterion exploring the right ventricle can predict the efficacy and\u002For safeness of recruitment maneuvers in patients suffering from acute respiratory distress syndrome.",[12],"Device: Echocardiography",[14],{"type":15,"name":9,"description":16,"armGroupLabels":17,"otherNames":18},"DEVICE","In the study RVSTAR, all the patients included will undergo an echocardiography in order to find an echocardiographic criterion predictive of the inefficacy and\u002For unsafeness of recruitment maneuver.",[9],null,[20],{"name":21,"affiliation":22,"role":23},"Guillaume Besch","Centre Hospitalier Universitaire Besançon","STUDY_DIRECTOR",[25],{"facility":26,"status":18,"city":27,"state":18,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":18},"CHU Besançon","Besançon","25000","France","FR",{"type":32,"coordinates":33},"Point",[34,35],6.01815,47.24878,{"lat":35,"lon":34},{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Guillaume BESCH","MD","100191527","echocardiography-predictive-of-the-inefficacy-andor-of-the-unsafeness-of-recruitment-maneuvers-in-patients-with-acute-respiratory-distress-syndrome-100191527",false,"NCT01768949","Echocardiography Predictive of the Inefficacy and\u002For of the Unsafeness of Recruitment Maneuvers in Patients With Acute Respiratory Distress Syndrome.","Identification of Echocardiographic Criteria Predictive of the Inefficacy and\u002For the Unsafeness of Recruitment Maneuvers in Patients Suffering From Acute Respiratory Distress Syndrome","RV STAR","Inclusion Criteria:\n\n* Endotracheal mechanical ventilation for acute hypoxemic respiratory failure lasting for one week or less\n* A ratio of the partial pressure of arterial oxygen (PaO2 measured in millimeters of mercury) to the fraction of inspired oxygen (FiO2 which is unitless) of 300 mmHg or less and inspired fraction of oxygen FiO2 of more than 50 %\n* A positive end-expiratory pressure of 5 cm of water or higher\n* A tidal volume of 6 to 8 ml per kilogram of predicted body weight\n* Bilateral opacities on chest radiography not fully explained by effusions, lobar\u002Flung collapse, or nodules\n* Respiratory failure not fully explained by cardiac failure or fluid overload\n* Written and informed consent\n* Adult patients at least 18 years of age\n* Ventilatory criteria (PaO2\u002FFiO2 of 300 mmHg or less and Positive End Expiratory Pressure of 5 cm of water or higher) and radiologic criteria (Bilateral opacities on chest radiography not fully explained by effusions, lobar\u002Flung collapse, or nodules) lasting more than 24 hours\n\nExclusion Criteria:\n\n* Endotracheal mechanical ventilation for acute hypoxemic respiratory failure lasting for more than one week\n* Age younger than 18 years old\n* No written and informed consent\n* Known pregnancy and\u002For breastfeeding\n* Increased intracranial pressure\n* A ratio of the partial pressure of arterial oxygen (PaO2 measured in millimeters of mercury) to the fraction of inspired oxygen (FiO2 which is unitless) higher than 300 mmHg\n* Positive end expiratory pressure of less than 5 mmHg\n* Ventilatory criteria (PaO2\u002FFiO2 of 300 mmHg or less and Positive End Expiratory Pressure of 5 cm of water or higher) and radiologic criteria (Bilateral opacities on chest radiography not fully explained by effusions, lobar\u002Flung collapse, or nodules) lasting less than 24 hours\n* Severe chronic respiratory disease requiring long-term oxygen therapy or mechanical ventilation at home\n* Severe chronic liver disease\n* Barotrauma such as pneumothorax\n* Hemodynamic failure needing more than 3 milligrams per hour of noradrenalin and\u002For more than 2 milligrams per hour of adrenalin and or rising doses of vasopressors and\u002For vascular filling exceeding 500 milliliters in the preceding hour\n* Arrhythmias such as : ventricular tachycardia, ventricular fibrillation, third degree atrioventricular block\n* Atrial fibrillation","ALL","18 Years",{"count":52,"type":53},30,"ACTUAL","INTERVENTIONAL",[56],"NA","The purpose of the study RVSTAR is to evaluate whether echocardiographic criteria exploring the right ventricle can predict the inefficacy and\u002For the unsafeness of recruitment maneuvers in patients suffering from acute respiratory distress syndrome",[59],"Acute Respiratory Distress Syndrome",[61,9,62],"Acute respiratory distress syndrome","Recruitment maneuver","COMPLETED","2017-01-30",{"date":66,"type":67},"2017-01-31","ESTIMATED",{"date":69,"type":18},"2013-02",{"date":71,"type":53},"2017-01",{"name":5,"class":6},1]