[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649381":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":29,"responsibleParty":45,"collaborators":25,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":25,"enrollmentInfo":59,"targetDuration":25,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":72,"whyStopped":25,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Mindfulness-centered stress management AI chatbot","EXPERIMENTAL","Participants will receive mindfulness-centered stress management AI chatbot.",[13],"Behavioral: Mindfulness-centered stress management AI chatbot",{"label":15,"type":16,"description":17,"interventionNames":18},"Psychoeducation","ACTIVE_COMPARATOR","Participants will receive psychoeducation reading materials.",[19],"Behavioral: Psychoeducation",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","An investigational, web-based conversational AI chatbot providing preventive, low-intensity psychological support for Chinese MSM experiencing mild-to-moderate stress. It has the following functions: (1) Built on a Chinese open-source LLM optimized through RAG to deliver culturally adapted, empathetic responses addressing minority stress, stigma, and identity concealment. (2) Delivers interactive, 10-20 min guided mindfulness-based stress reduction exercises (grounding, self-compassion, sleep-support, etc).",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Participants receive standardized, text-based psychoeducational readings covering general stress, coping concepts, and mental health awareness. The delivery contains no interactive features, conversational elements, or guided mindfulness coaching.",[15],[30],{"facility":5,"status":25,"city":31,"state":25,"zip":25,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Hong Kong","HK",{"type":34,"coordinates":35},"Point",[36,37],114.17469,22.27832,{"lat":37,"lon":36},[40],{"name":41,"role":42,"phone":43,"phoneExt":25,"email":44},"Shuochi Wei","CONTACT","852-68744705","weisc@connect.hku.hk",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","WEI Shuochi","PhD Candidate","100649381","effectiveness-of-a-mindfulness-centered-stress-management-ai-chatbot-to-reduce-stress-and-enhance-mental-health-among-men-who-have-sex-with-men-in-china-100649381",false,"NCT07732621","Effectiveness of A Mindfulness-centered Stress Management AI Chatbot to Reduce Stress and Enhance Mental Health Among Men Who Have Sex With Men in China","Effectiveness of A Mindfulness-centered Stress Management AI Chatbot to Reduce Stress and Enhance Mental Health Among Men Who Have Sex With Men in China: A Randomized Controlled Trial Study","MSM","Inclusion Criteria:\n\n1. Age ≥ 18 years.\n2. Chinese\n3. Self-identify as MSM.\n4. Own a smartphone to ensure compatibility with the intervention platform.\n5. Mild to moderate perceived stress, defined as Chinese Perceived Stress Scale (PSS-14) score \\\u003C 43.\n\nExclusion Criteria:\n\n1. Diagnosed with an acute severe mental disorder, such as psychosis, major depressive disorder, or anxiety disorder;\n2. Currently receiving psychotherapy at enrollment.\n3. Report moderately severe to severe depressive symptoms, defined as a PHQ-9 total score greater than 14.\n4. Unable to provide online informed consent or complete study procedures.","MALE","18 Years",{"count":60,"type":61},76,"ESTIMATED","INTERVENTIONAL",[64],"NA","The goal of this randomized controlled trial is to evaluate the effectiveness of a mindfulness-centered stress management AI chatbot in reducing perceived stress and enhancing mental health among Chinese men who have sex with men (MSM).\n\nThe main questions it aims to answer are:\n\n1. Does the AI chatbot show a greater reduction in perceived stress compared to standardized psychoeducational materials?\n2. Does the AI chatbot improve mental health outcomes, including depressive and anxiety symptoms, subjective well-being, and emotion regulation?\n\nResearchers will compare the AI chatbot to a control group receiving psychoeducational materials to see if the chatbot works to reduce stress and improve mental health.\n\nParticipants will:\n\n1. Be randomized to use the AI chatbot (recommended at least 2 sessions per week, 10-15 minutes per session) or read psychoeducational materials (2 times per week) for 4 weeks.\n2. Complete online self-report questionnaires at baseline, post-intervention (Week 4), and 4-week follow-up.",[67],"Stress (Psychology)",[69,70,71],"stress","sexual minority","mindfulness","NOT_YET_RECRUITING","2026-08-17",{"date":75,"type":76},"2026-08-19","ACTUAL",{"date":78,"type":61},"2026-07-31",{"date":80,"type":61},"2027-03-31",{"name":5,"class":6},1]