[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100356345":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":32,"responsibleParty":48,"collaborators":25,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":25,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":25,"enrollmentInfo":61,"targetDuration":25,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":76,"whyStopped":25,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Xuzhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"intervention group","EXPERIMENTAL","Durg：0.375% Ropivacaine and 1% lidocaine\n\ntopical local anesthesia of pulmonary vein with lidocaine+ropivacaine at the beginning and the end of surgery operation.\n\nBlock vagus nerve with lidocaine+ropivacaine 1ml after exposing the pleural apex",[13],"Procedure: topical local anesthesia of pulmonary vein combined with vagus nerve block",{"label":15,"type":16,"description":17,"interventionNames":18},"normal saline group","PLACEBO_COMPARATOR","Same volume of normal saline will be administrated",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","topical local anesthesia of pulmonary vein combined with vagus nerve block","Injecting 1% lidocaine 1.5ml+0.375% ropivacaine 1.5ml into vascular sheaths of all pulmonary vein of the surgery side at the beginning of surgery operation.\n\nWrapping all pulmonary vein of the surgery side with cotton sheet infiltrated with 1% lidocaine+0.375% ropivacaine at the end of surgery operation.\n\nBlocking vagus nerve above the aortic vein on the right side of the trachea with 1% lidocaine 1ml+0.375% ropivacaine 1ml after exposing the pleural apex.",[9,15],null,[27],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Junli Cao","CONTACT","+86 15162160809","caojl0310@yahoo.com.cn",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":25,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Department of Anesthesiology of the Affiliated Hospital of Xuzhou Medical University","RECRUITING","Xuzhou","Jiangsu","China","CN",{"type":41,"coordinates":42},"Point",[43,44],117.28386,34.20442,{"lat":44,"lon":43},[47],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Han Yuan","Doctor-in-charge of Anesthetist","100356345","effects-of-topical-local-anesthesia-of-pulmonary-vein-combined-with-vagus-nerve-block-on-the-incidence-of-atrial-fibrillation-after-thoracic-surgery-100356345",false,"NCT03919786","Effects of Topical Local Anesthesia of Pulmonary Vein Combined With Vagus Nerve Block on the Incidence of Atrial Fibrillation After Thoracic Surgery","Effects of Topical Local Anesthesia of Pulmonary Vein Combined With Vagus Nerve Block on the Incidence of Atrial Fibrillation After Thoracic Surgery: a Double-blinded Randomized Placebo Controlled Trials","Inclusion Criteria:\n\n* Thoracoscopic lobectomy and bilobectomy\n* ASA class I-III\n* Age is greater than or equal to 50 years old\n* Han Nationality, mother tongue is chinese\n* The people signed informed consent\n\nExclusion Criteria:\n\n* history of chronic atrial arrhythmia\n* sick sinus syndrome\n* history of second-degree atrioventricular block\n* taking class I or class III antiarrhythmic drugs or β-receptor blocker\n* history of radiofrequency ablation\n* hyperthyroidism\n* contraindications of ropivacaine, lidocaine\n* pregnancy and lactation","ALL","50 Years",{"count":62,"type":63},150,"ESTIMATED","INTERVENTIONAL",[66],"NA","This study intends to explore a new therapy to reduce the incidence of atrial fibrillation in thoracic patient who receive video-assisted thoracoscopic lobectomy .The results of the study are to assess the effects of this new intervention on the incidence，duration of atrial fibrillation and other complications including postoperative delirium after video-assisted thoracoscopic lobectomy .And reducing the burden of POAF on patients and their families, hospitals and public resources.",[69],"Atrial Fibrillation",[71,72,73,74,75],"postoperative atrial fibrillation","lobectomy","thoracic surgery","vagus nerve block","pulmonary myocardial sleeve","UNKNOWN","2019-12-03",{"date":79,"type":80},"2019-12-05","ACTUAL",{"date":82,"type":80},"2019-04-01",{"date":84,"type":63},"2020-07",{"name":50,"class":6},1]