[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621058":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":25,"locations":30,"responsibleParty":38,"collaborators":25,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":25,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":25,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":61,"whyStopped":25,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Derma Techno Pakistan","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A (tab bilastine 40mg )","ACTIVE_COMPARATOR","patients received oral tab bilastine 20 mg twice daily for 6 weeks",[13],"Drug: tab bilastine 20 mg",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B ( tab bilastine 20 mg + tab levocetrizine 5 mg )","patients received tab bilastine 20 mg in the morning and tab levocitrizine 5 mg in the evening for 6 weeks",[18],"Drug: tab bilastine 20 mg + tab levocetrizine 5 mg",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","tab bilastine 20 mg","tab bilastine 20 mg given orally twice a day for 6 weeks",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"tab bilastine 20 mg + tab levocetrizine 5 mg","tab levocitrizine 5 mg given orally at night with combination of tab bilastine 20 mg in the morning for 6 weeks",[15],[31],{"facility":32,"status":25,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":25,"geoPoint":25,"contacts":25},"combined military hospital ,Okara","Okāra","Punjab Province","56300","Pakistan","PK",{"type":39,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100621058","efficacy-of-bilastine-up-dosing-40-mg--versus-combination-of-bilastine-20-mg-with-levocitirizine-5-mg-in-the-treatment-of-chronic-spontaneous-urticaria-100621058",false,"NCT07365683","Efficacy of Bilastine Up-dosing (40 mg ) Versus Combination of Bilastine (20 mg )With Levocitirizine (5 mg) in the Treatment of Chronic Spontaneous Urticaria","A Prospective Randomized Non-blinded Study of Safety and Efficacy of Bilastine Up-dosing (40 mg) Versus Combination of Bilastine (20 mg) With Levocetrizine (5mg) in the Treatment of Chronic Spontaneous Urticaria","Inclusion Criteria:\n\n* Patients with diagnosis of CSU as per operational definitions.\n* Patients already taking Bilastine 20 mg and still getting new lesions.\n* UAS7 score \\>3\n* Age range of 18-70 years\n* Both male and female patients\n\nExclusion Criteria:\n\n* • women Patients who have already received treatment of CSU other than Bilastine.\n\n  * Patients taking oral or topical corticosteroids\n  * Pregnant or lactating\n  * Patients with hereditary angioedema, atopic dermatitis, systemic immune disorders, collagen vascular diseases, immunocompromised status, Chronic liver or kidney failures","ALL","18 Years","70 Years",{"count":51,"type":52},60,"ACTUAL","INTERVENTIONAL",[55],"NA","This study aims to compare the effectiveness and safety of two commonly used antihistamines, bilastine 20 mg and levocetirizine 5 mg, in patients diagnosed with chronic urticaria. Chronic urticaria is a skin condition characterized by recurrent itchy wheals that significantly affect quality of life.\n\nEligible participants will be randomly assigned to receive either bilastine or levocetirizine for a defined treatment period. The severity of symptoms, improvement in itching and wheals, and any adverse effects will be assessed during follow-up visits.\n\nThe results of this study will help determine which treatment provides better symptom control with fewer side effects in patients with chronic urticaria.",[58],"Chronic Spontaneous Urticaria (CSU)",[60],"up-dosing +combination","COMPLETED","2026-01-23",{"date":64,"type":52},"2026-01-26",{"date":66,"type":52},"2025-08-18",{"date":68,"type":52},"2026-01-17",{"name":5,"class":6},1]