[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569341":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":34,"centralContacts":10,"locations":39,"responsibleParty":72,"collaborators":10,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":76,"sex":82,"minAge":10,"maxAge":10,"enrollmentInfo":83,"targetDuration":10,"studyType":86,"phases":10,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":95,"whyStopped":10,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Centre Hospitalier de Cayenne","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Single group",null,"Patient of any age with suspicious skin lesions",[13,14,15,16],"Other: Clinical and epidemiological data","Other: Parasitological samples","Other: Assessment of clinical course and response to treatment","Other: DLQI questionnaire",[18,22,26,30],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"Clinical and epidemiological data","Collection of clinical and epidemiological data on day 0",[9],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"Parasitological samples","Parasitological samples : smear for on-site analysis and swabs to be sent to the Cayenne Hospital for PCR at day 0",[9],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"Assessment of clinical course and response to treatment","Follow-up visit with assessment of clinical course and response to treatment at M6",[9],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":10},"DLQI questionnaire","DLQI questionnaire at M6",[9],[35],{"name":36,"affiliation":37,"role":38},"Romain BLAIZOT, MCU-PH","Centre Hospitalier de Cayenne (CHC)","PRINCIPAL_INVESTIGATOR",[40,52,62],{"facility":41,"status":10,"city":42,"state":43,"zip":44,"country":43,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":10},"Faculté de Médecine et d'Odonto-Stomatologie \u002F Université des Sciences, des Techniques et des Technologies de Bamako, Mali","Bamako","Mali","BP 1805","ML",{"type":47,"coordinates":48},"Point",[49,50],-7.97522,12.60915,{"lat":50,"lon":49},{"facility":53,"status":10,"city":54,"state":55,"zip":10,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":61,"contacts":10},"Faculté de médecine\u002FUniversité André Salifou BP806 Zinder NIGER","Zinder","Niger","NE",{"type":47,"coordinates":58},[59,60],8.9881,13.80716,{"lat":60,"lon":59},{"facility":63,"status":10,"city":64,"state":65,"zip":10,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":71,"contacts":10},"Service de Dermatologie, CHR TSEVIE, Faculté des Sciences de la Santé, Université de Lomé","Lomé","Togo","TG",{"type":47,"coordinates":68},[69,70],1.22154,6.12874,{"lat":70,"lon":69},{"type":73,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100569341","epidemiology-of-cutaneous-leishmaniasis-in-niger-mali-togo--mapping-of-clinical-cases-species-reservoirs-and-vectors-of-the-disease-100569341",false,"NCT06692985","Epidemiology of Cutaneous Leishmaniasis in Niger, Mali, Togo : Mapping of Clinical Cases, Species, Reservoirs and Vectors of the Disease","Sentinel Surveillance of Cutaneous Leishmaniasis in Sub-Saharan Africa Based on Non-invasive Molecular Diagnostics: Mapping of Human Cases, Description of Leishamania Species Involved","LEISHAFRICA","Inclusion Criteria:\n\n* Clinical suspicion of cutaneous leishmaniasis during a consultation in one of the partner centres (or by the country physicians) = presence of an ulcerative lesion, papules or nodules\n* Obtaining informed and voluntary consent\n\nNon inclusion \u002F Exclusion Criteria:\n\n* Objection to the use of their data and\u002For the taking of the questionnaire\n* Refusal to participate\n* Withdrawal of participation","ALL",{"count":84,"type":85},270,"ACTUAL","OBSERVATIONAL","Cutaneous leishmaniasis is a neglected tropical disease caused by parasites belonging to the genus Leishmania. This infection can cause skin and sometimes mucous membrane lesions with significant damage. LC has been little studied in sub-Saharan Africa where its incidence is probably underestimated, especially in West Africa. Leishmania major is almost the only isolated species in this region, although recent data suggest the existence of other species, such as L. enrietti. It is said that CL is only present in the arid areas of Africa, but recent outbreaks in wetlands and forests tend to contradict this theory. Due to the lack of availability of the PCR method, the diagnosis of LC in West Africa, especially in Mali, is rarely confirmed. Treatment options are also scarce and their effectiveness is poorly documented. The objectives of this study are to map the occurrence of LC cases with molecular biology confirmation in Niger, Mali and Togo; to determine the different species involved in human cases; evaluate the different treatment options available.",[89],"Cutaneous Leishmaniasis",[91,92,43,65,55,93,94],"Phylogeny","Sub-Saharian Africa","Sentinel surveillance","Therapeutic","COMPLETED","2024-11-18",{"date":98,"type":85},"2024-11-20",{"date":100,"type":85},"2023-04-01",{"date":102,"type":85},"2024-03-01",{"name":5,"class":6},3]