[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100135040":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":13,"centralContacts":10,"locations":18,"responsibleParty":32,"collaborators":35,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":45,"sex":46,"minAge":47,"maxAge":10,"enrollmentInfo":48,"targetDuration":10,"studyType":51,"phases":10,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":59,"whyStopped":10,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"Monash University","OTHER",[8,11],{"label":9,"type":10,"description":10,"interventionNames":10},"Healthy volunteers",null,{"label":12,"type":10,"description":10,"interventionNames":10},"Acute decompensated heart failure",[14],{"name":15,"affiliation":16,"role":17},"Henry Krum, MBBS FRACP PhD","Monash University \u002F Alfred Hospital","PRINCIPAL_INVESTIGATOR",[19],{"facility":20,"status":10,"city":21,"state":22,"zip":23,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":10},"Alfred Hospital","Melbourne","Victoria","3004","Australia","AU",{"type":27,"coordinates":28},"Point",[29,30],144.96332,-37.814,{"lat":30,"lon":29},{"type":17,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Prof Henry Krum","Professor",[36],{"name":37,"class":6},"The Alfred","100135040","evaluation-of-circulating-levels-of-adult-stem-cells-in-the-peripheral-blood-of-patients-with-acute-decompensated-heart-failure-and-following-stabilization-in-comparison-with-healthy-volunteers-100135040",false,"NCT01027403","Evaluation of Circulating Levels of Adult Stem Cells in the Peripheral Blood of Patients With Acute Decompensated Heart Failure and Following Stabilization, in Comparison With Healthy Volunteers","CIRCSTEM-HF","Inclusion Criteria:\n\n* Men or women 18 years or older\n* Hospitalized for the management of ADHF or diagnosed with ADHF within 48 hours after being hospitalized for another reason (patients\u002Fcases ONLY)\n* Signed (by the subjects or their legally acceptable representatives) informed consent\n\nExclusion Criteria:\n\n* Hospitalized for \\> 48 hours before study enrollment\n* Likely to be discharged from the hospital in 24 hours or less\n* Current haematological disorder or haematological malignancy\n* Active infection \u002F sepsis\n* Major organ insufficiency (other than heart failure in heart failure patients)\n* Pregnancy\n* Healthy volunteers found to have signs and\u002For symptoms of heart failure on screening.",true,"ALL","18 Years",{"count":49,"type":50},30,"ACTUAL","OBSERVATIONAL","Despite advances in medical technology, heart failure remains a major cause of illness on a global scale. Medical research, over recent years, has shown that adult stem cells (as opposed to embryonic stem cells) are present in most organs of adult humans. Their exact function is however poorly understood. An improved understanding of what these stem cells do and how they work is essential if effective stem cell treatments are to be developed in future.\n\nThe project seeks to examine the levels of a number of different types of stem cells in patients with heart failure, compared to healthy volunteers. The project also aims to measure stem cell levels in patients with heart failure at the time of a sudden worsening in their condition and then later in the same patients following recovery.\n\nThe project entails the taking of blood samples in order to measure the stem cell levels in the blood. The study does NOT involve any form of treatment with stem cells. Two groups of patients will be studied; patients with heart failure and healthy volunteers.",[54],"Heart Failure",[56,57,58,12],"Heart failure","Adult stem cells","Circulating stem cells","COMPLETED","2015-06-02",{"date":62,"type":63},"2015-06-04","ESTIMATED",{"date":65,"type":10},"2009-12",{"date":67,"type":50},"2014-12",{"name":5,"class":6},1]