[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586858":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":24,"locations":29,"responsibleParty":42,"collaborators":24,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":24,"enrollmentInfo":53,"targetDuration":24,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":66,"whyStopped":24,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Medical University of Bialystok","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SRP","EXPERIMENTAL","In the control group (20 subjects) SRP was performed alone.",[13],"Procedure: SRP",{"label":15,"type":10,"description":16,"interventionNames":17},"SRP+iPRF","The test group consisted of 20 people participants who underwent the SRP procedure and then i-PRF was administered into the pockets.",[18],"Biological: SRP+iPRF",[20,25],{"type":21,"name":15,"description":22,"armGroupLabels":23,"otherNames":24},"BIOLOGICAL","SRP (scaling and root planing) with iPRF (injectable platelet-rich fibrin)",[15],null,{"type":26,"name":9,"description":27,"armGroupLabels":28,"otherNames":24},"PROCEDURE","SRP (scaling and root planing)",[9],[30],{"facility":31,"status":24,"city":32,"state":24,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":24},"Department of Integrated Dentistry, Medical University of Białystok","Bialystok","15-089","Poland","PL",{"type":37,"coordinates":38},"Point",[39,40],23.16433,53.13333,{"lat":40,"lon":39},{"type":43,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100586858","evaluation-of-the-influence-of-prf-platelet-rich-fibrin-on-the-clinical-parameters-and-the-concentration-of-selected-inflammation-mediators-in-gcf-gingival-crevice-fluid-of-patients-with-periodontitis-100586858",false,"NCT06920849","Evaluation of the Influence of PRF (Platelet-rich Fibrin) on the Clinical Parameters and the Concentration of Selected Inflammation Mediators in GCF (Gingival Crevice Fluid) of Patients With Periodontitis","PRFperio","Inclusion Criteria:\n\n* clinical and radiological features of periodontitis in stage II, III or IV\n* presence of at least 4 teeth and at least 2 pockets (localized not on the same tooth) with a depth of at least 5 mm in each quadrant\n\nExclusion Criteria:\n\n* periodontal treatment within 3 months prior to the study;\n* antibiotic therapy within 3 months prior to the study;\n* smoking; presence of systemic diseases affecting periodontal healing, i.e.: immunosuppressive diseases, diabetes, osteoporosis, AIDS, hypertension treated with calcium channel blockers;\n* use of steroids or other immunosuppressive drugs;\n* coagulation disorders and use of drugs affecting its mechanisms;\n* pregnant and breastfeeding women","ALL","18 Years",{"count":54,"type":55},40,"ACTUAL","INTERVENTIONAL",[58],"NA","Assessment of the influence of injectable platelet-rich fibrin (i-PRF) on the clinical parameters and the inflammation mediators levels in the gingival crevicular fluid (GCF) in patients with periodontitis.",[61,62],"Periodontal Disease","Periodontitis",[64,9,65],"periodontitis","PRF","ACTIVE_NOT_RECRUITING","2025-04-03",{"date":69,"type":55},"2025-04-10",{"date":71,"type":55},"2022-04-01",{"date":73,"type":74},"2025-06-30","ESTIMATED",{"name":5,"class":6},1]