[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100217204":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":10,"centralContacts":10,"locations":30,"responsibleParty":42,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":67,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":10,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Ain Shams Maternity Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"procalcitonin in blood",null,"-Group 1: Healthy preterm Group: will include 50 pregnant females all at 24-34 weeks of gestational age .",[13],"Drug: procalcitonin",{"label":15,"type":10,"description":16,"interventionNames":17},"plasma of blood","-Group 2: Preterm premature rupture of membrane Group include 50 pregnant women",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"procalcitonin,prematureruptureofmembrane in blood","Complete history including (special habits like smoking and alcohol taking, menstrual history especially LMP, medical diseases, past obstetric history including duration, mode of delivery for each pregnancy, and if there were fetal or maternal complications).\n\nPhysical examination including (general condition, height, weight, vital signs).-Ultrasound to execlude multiple pregnancies, IUFD and to confirm oligohydraminos in group2.\n\nThe venous blood samples will be taken for measuring of -Procalcitonin in mothors -CRP and WBCs in mothers to detect infection -CRP in neonates of mothers of group 2.\n\nThey will be asked for their permission and consent.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DRUG","procalcitonin","In patient with preterm premature rupture of membrane (PPROM) is the procalcitonin can be used to predict intra-amniotic subclinical infection?",[15,9,19],[29],"plasma",[31],{"facility":5,"status":10,"city":32,"state":10,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":10},"Cairo","02","Egypt","EG",{"type":37,"coordinates":38},"Point",[39,40],31.24967,30.06263,{"lat":40,"lon":39},{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Alaa Sayed Hassanin","Lecturer","100217204","evaluation-of-the-role-of-plasma-procalcitonin-in-prediction-of-intra-amniotic-infection-in-preterm-premature-rupture-of-membrane-100217204",false,"NCT02104791","Evaluation of the Role of Plasma Procalcitonin in Prediction of Intra-amniotic Infection in Preterm Premature Rupture of Membrane","Procalcitonin Has a Role to Play in Prediction of Intra-amniotic Subclinical Infection.","Patients are with singleton pregnancies. Rupture of membranes will be diagnosed by history, sterile speculum examination to confirm fluid leakage from the cervical canal and ultrasound to confirm oligohydraminos.\n\nSubclinical infection will be detected with laboratory indices (WBC count of ≥15, 000 c\u002Fmm3, CRP of ≥1 mg\u002FdL) without any clinical symptoms and signs of infection as urinary tract infection in group 1 patients.\n\nWomen with multiple pregnancies. Clinical signs of infection as (fever,abdominal tendernes). Cervical dilatations of 2 cm or more. Maternal disease like diabetes or fetal complications like intra-uterine fetal death.\n\nInclusion Criteria:\n\n\\-\n\nExclusion Criteria:\n\n\\-",true,"FEMALE","20 Years","40 Years",{"count":58,"type":59},100,"ACTUAL","OBSERVATIONAL","It is hypothesized that the procalcitonin has a role to play in prediction of intra-amniotic subclinical infection.",[63],"Intra-amniotic Subclinical Infection.",[65,66],"Procalcitonin","intra-amniotic subclinical infection.","UNKNOWN","2014-04-03",{"date":70,"type":71},"2014-04-04","ESTIMATED",{"date":73,"type":10},"2014-05",{"name":5,"class":6},1]