[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601431":3},{"organization":4,"armGroups":7,"interventions":34,"overallOfficials":39,"centralContacts":39,"locations":52,"responsibleParty":65,"collaborators":67,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":39,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":39,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":93,"overallStatus":104,"whyStopped":39,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"eMKa MED Medical Center","OTHER",[8,14,19,24,29],{"label":9,"type":10,"description":11,"interventionNames":12},"Autogenous transplant of fragmented adipose tissue taken from abdominal integuments","EXPERIMENTAL","Treatment of chondromalacia of the cartilage in the knee joint with the use of autogenous graft of fragmented adipose tissue taken from the abdominal wall - MyStem, Lipogems, Arthrex.",[13],"Procedure: Autogenous transplant of fragmented adipose tissue taken from abdominal integuments",{"label":15,"type":10,"description":16,"interventionNames":17},"PRP GF (platelet-rich plasma with growth factors)","Treatment of chondromalacia of the cartilage in the knee joint with the use of PRP GF (platelet-rich plasma with growth factors: Ycellbio, ACP Arthrex, Neoregen, PhankPharma).",[18],"Procedure: PRP GF (platelet-rich plasma with growth factors)",{"label":20,"type":10,"description":21,"interventionNames":22},"Mesenchymal cells centrifuged from bone marrow cells taken from the iliac crest","Treatment of cartilage chondromalacia in the knee joint using mesenchymal cells centrifuged from bone marrow cells taken from the iliac crest - (Harvest, Arthrex),",[23],"Procedure: Mesenchymal cells centrifuged from bone marrow cells taken from the iliac crest",{"label":25,"type":10,"description":26,"interventionNames":27},"Hyaluronic acid - low molecular weight","Treatment of chondromalacia of the cartilage in the knee joint with the use of Hyaluronic Acid - low molecular weight (Synvisc, Biolevox, ArtiAidPlus).",[28],"Procedure: Hyaluronic acid - low molecular weight",{"label":30,"type":10,"description":31,"interventionNames":32},"Hyaluronic acid - cross-linked","Treatment of chondromalacia of the cartilage in the knee joint with the use of cross-linked Hyaluronic Acid Arti Aid Plus, Synovial, Durolain, StavOn, Collagenu - Guna, Orthokine.",[33],"Procedure: Hyaluronic acid - cross-linked",[35,40,43,46,49],{"type":36,"name":9,"description":37,"armGroupLabels":38,"otherNames":39},"PROCEDURE","Treatment of chondromalacia of the cartilage in the knee joint by arthroscopic technique with the use of autogenous graft of fragmented adipose tissue taken from the abdominal wall.",[9],null,{"type":36,"name":15,"description":41,"armGroupLabels":42,"otherNames":39},"Treatment of chondromalacia of the cartilage in the knee joint by arthroscopic technique with the use of PRP GF (platelet-rich plasma with growth factors)",[15],{"type":36,"name":20,"description":44,"armGroupLabels":45,"otherNames":39},"Treatment of cartilage chondromalacia in the knee joint by arthroscopic technique using mesenchymal cells centrifuged from bone marrow cells taken from the iliac crest",[20],{"type":36,"name":25,"description":47,"armGroupLabels":48,"otherNames":39},"Treatment of chondromalacia of the cartilage in the knee joint with the use of Hyaluronic Acid - low molecular weight",[25],{"type":36,"name":30,"description":50,"armGroupLabels":51,"otherNames":39},"Treatment of chondromalacia of the cartilage in the knee joint by arthroscopic technique with the use of cross-linked Hyaluronic Acid Arti Aid Plus, Synovial, Durolain, StavOn, Collagenu",[30],[53],{"facility":5,"status":39,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":39},"Wroclaw","Dolnośląsk","53-110","Poland","PL",{"type":60,"coordinates":61},"Point",[62,63],17.03006,51.10286,{"lat":63,"lon":62},{"type":66,"investigatorFullName":39,"investigatorTitle":39,"investigatorAffiliation":39,"oldNameTitle":39,"oldOrganization":39},"SPONSOR",[68],{"name":69,"class":6},"Wroclaw Medical University","100601431","evaluation-of-treatment-of-osteoarthritis-of-the-knee-in-the-form-of-chondromalacia-of-the-articular-cartilage-treated-in-the-arthroscopic-technique-with-the-use-ofautogenous-transplantation-of-fragmented-adipose-tissueprp-gfmesenchymal-cellshyaluronic-acid-low-molecular-weight-and-cross-linked-100601431",false,"NCT07110402","Evaluation of Treatment of Osteoarthritis of the Knee in the Form of Chondromalacia of the Articular Cartilage Treated in the Arthroscopic Technique With the Use of:Autogenous Transplantation of Fragmented Adipose Tissue,PRP GF,Mesenchymal Cells,Hyaluronic Acid-low Molecular Weight and Cross-linked","Clinical and Comparative Evaluation of Treatment Results for Osteoarthritis of the Knee in the Form of Chondromalacia of the Articular Cartilage Treated in the Arthroscopic Technique With the Use of: Autogenous Transplant of Fragmented Adipose Tissue Taken From Abdominal Integuments, PRP GF (Platelet-rich Plasma With Growth Factors), Mesenchymal Cells Centrifuged From Bone Marrow Cells Taken From the Iliac Crest, Hyaluronic Acid - Low Molecular Weight, Hyaluronic Acid - Cross-linked","Inclusion Criteria:\n\n* Surgery for ACL damage to the knee joint;\n* Arthroscopic surgery;\n* No prior knee surgical interventions;\n* No additional pathologies in this anatomical area;\n* Informed consent of the patient to participate in the study.\n\nExclusion Criteria:\n\n* Previous surgical interventions in the examined anatomical area;\n* Additional pathologies in this area identified as part of preoperative diagnostics;\n* Damage to the second knee joint;\n* Failure to comply with the rigor of the same rehabilitation treatment protocol.","ALL","18 Years","70 Years",{"count":81,"type":82},150,"ACTUAL","INTERVENTIONAL",[85],"NA","The main objective of the research project is to evaluate the results of the treatment of chondromalacia of the cartilage in the knee joint with the use of: autogenous transplantation of fragmented adipose tissue taken from the abdominal wall - (MyStem, Lipogems, Arthrex).\n\nPRP GF (platelet-rich plasma with growth factors) (Ycellbio, ACP Arthrex, Neoregen, FrankPharma), Mesenchymal cells centrifuged from bone marrow cells taken from the iliac crest - (Harvest, Arthrex), Hyaluronic acid - low molecular weight (Synvisc, Biolevox, ArtiAidPlus), Hyaluronic acid - cross-linked Arti Aid Plus, Synovial, Durolain, StavOn, Collagen - Guna, Orthokine.\n\nThe specific objectives are: to compare the results of treatment of analogous zones of cartilage defects in the knee joint obtained in the study groups using two methods: microfractures and microfractures with simultaneous intra-articular injection of autogenous cartilage graft and PRP GF (Auto Cart-Arthrex method). The results for the operated limb in both groups will be compared both between the groups and with the results of clinical and biomechanical tests for the non-operated limbs.",[88,89,90,91,92],"Osteoarthritis, Knee","Chondral Defect","Chondromalacia, Left Knee","Chondromalacia, Right Knee","Articular Cartilage Disorder of Knee",[94,95,96,97,98,99,100,101,102,103],"Cartilage","Damage","Chondral defect","Chondromalacja","Techniques","Articular Cartilage Treated","Autogenous Transplant","PRP GF","Hyaluronic Acid","Mesenchymal Cells","COMPLETED","2025-08-05",{"date":107,"type":82},"2025-08-07",{"date":109,"type":82},"2022-12-12",{"date":111,"type":82},"2024-12-12",{"name":5,"class":6},1]