[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100389316":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":11,"centralContacts":25,"locations":35,"responsibleParty":52,"collaborators":11,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":11,"enrollmentInfo":63,"targetDuration":11,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":11,"overallStatus":72,"whyStopped":11,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Gustave Roussy, Cancer Campus, Grand Paris","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with cancer","EXPERIMENTAL",null,[13,14],"Procedure: Tissue sampling","Procedure: Blood sampling",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":11},"PROCEDURE","Tissue sampling","Collection of a sample of tumor tissue and a sample of adjacent or counter lateral healthy tissue (if possible) from the surgical room",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"Blood sampling","Collection of a 30mL peripheral blood sample in heparin at several times: during surgical and medical treatment (before surgery, before the start of mAbs and after mAbs)",[9],[26,32],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"Laurence ZITVOGEL, MD, PhD","CONTACT","0142114211","+33","laurence.zitvogel@gustaveroussy.fr",{"name":33,"role":28,"phone":29,"phoneExt":30,"email":34},"Agathe DUBUISSON, PhD","agathe.dubuisson@gustaveroussy.fr",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Gustave Roussy","RECRUITING","Villejuif","Val De Marne","94800","France","FR",{"type":45,"coordinates":46},"Point",[47,48],2.35992,48.7939,{"lat":48,"lon":47},[51],{"name":33,"role":28,"phone":29,"phoneExt":30,"email":34},{"type":53,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100389316","ex-vivo-evaluation-of-the-reactivity-of-the-immune-infiltrate-of-cancers-to-treatments-with-monoclonal-antibodies-targeting-the-immunomodulatory-pathways-100389316",false,"NCT04349293","Ex-vivo Evaluation of the Reactivity of the Immune Infiltrate of Cancers to Treatments With Monoclonal Antibodies Targeting the Immunomodulatory Pathways","MAB IN SITRO","Inclusion Criteria:\n\n1. Age greater than or equal to 18 years.\n2. Male and female sex.\n3. Any patient with cancer (see list in the body of the protocol) requiring treatment by surgical resection and \u002F or who will start treatment with mAb or BiTE.\n4. Patient information and signed informed consent.\n5. Subjects affiliated (or beneficiary) to a social security scheme\n\nPatients treated for immune complications by immunosuppressants may be included (corticosteroids, etc.).\n\nExclusion Criteria:\n\n1. History of severe systemic autoimmune disease.\n2. Pregnant or breastfeeding patient\n3. Impossibility or refusal to sign informed consent\n4. Patient under guardianship or curatorship, or deprived of liberty by a judicial or administrative decision","ALL","18 Years",{"count":64,"type":65},150,"ESTIMATED","INTERVENTIONAL",[68],"NA","Multicentric interventional prospective study with collection of biological samples as part of a routine care research",[71],"Cancer","UNKNOWN","2020-04-14",{"date":75,"type":76},"2020-04-16","ACTUAL",{"date":78,"type":76},"2016-09-08",{"date":80,"type":65},"2021-09",{"name":5,"class":6},1]