[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100457019":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":20,"locations":29,"responsibleParty":45,"collaborators":19,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":19,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":56,"minAge":19,"maxAge":19,"enrollmentInfo":57,"targetDuration":19,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":19,"overallStatus":66,"whyStopped":19,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Sohag University","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"infected non united fractures","patient of any age and any sex with infected non united fractures of long or short bones",[12],"Procedure: local debridement and local calcium sulfate loaded by antibiotics",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"PROCEDURE","local debridement and local calcium sulfate loaded by antibiotics","debridement of infected non united fractures and placement of local calcium sulfate loaded by antibiotic then follow up at regular intervals",[9],null,[21,26],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Abdelraheem m sonbol, resident","CONTACT","01121280438","abdelreheem011115@med.sohag.edu.eg",{"name":27,"role":23,"phone":28,"phoneExt":19,"email":19},"abdelrahman h khalifa, professor","01003701283",[30],{"facility":31,"status":32,"city":33,"state":19,"zip":19,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Sohag University Hospital","RECRUITING","Sohag","Egypt","EG",{"type":37,"coordinates":38},"Point",[39,40],31.69478,26.55695,{"lat":40,"lon":39},[43],{"name":44,"role":23,"phone":19,"phoneExt":19,"email":19},"Osama R ElSherif, professor",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Abdelraheem Mohamed Sonbol","Resident of orthopedic surgery","100457019","hardware-preservation-in-management-of-infected-non-united-or-delayed-united-fractures-of-long-or-short-bones-by-debridement-and-local-calcium-sulfate-loaded-by-antibiotics-100457019",false,"NCT05231148","Hardware Preservation in Management of Infected Non United or Delayed United Fractures of Long or Short Bones by Debridement and Local Calcium Sulfate Loaded by Antibiotics","Inclusion Criteria:\n\n* Patient at any age and of any sex with infected non united fracture of long or short bones\n\nExclusion Criteria:\n\n* Presence of previous vascular injury or pathological fracture\n* Refusal to participate\n* Inability to provide informed consent\n* Allergy or sensitivity to vancomycin or tobramycin\n* Patient with impaired renal function\n* Patient with hypercalcemia",true,"ALL",{"count":58,"type":59},10,"ESTIMATED","INTERVENTIONAL",[62],"NA","* Diagnosis of infection based on elevated serum markers of infection (ESR, CRP), discharging sinus, preoperative radiographs suggestive of bone infection and radiological findings . \\[6\\]\n* infected nonunion mean the bone has previous fracture , the bone not healed may be one of the reasons it didn't heal because there is sub-acute infection , there is low grade colonization into the bone or around the wound preventing the bone from healing , it different from infected fracture which occur fairly acutely. \\[6, 7\\]\n* Infected nonunion treated with systemic antibiotics alone, without using local antibiotic delivery systems associated with higher recurrence and reoperation rates. \\[7\\]\n* This led to the development and use of medical-grade calcium sulfate (CS), CS facilitates osseous healing in an osteoconductive fashion by filling the bone void and preventing fibrous tissue",[65],"Infected Non Union and Delayed Union in Fractures of Both Long and Short Bones","UNKNOWN","2023-03-21",{"date":69,"type":70},"2023-03-23","ACTUAL",{"date":72,"type":70},"2021-12-12",{"date":74,"type":59},"2023-10",{"name":5,"class":6},1]