[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100299682":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":22,"centralContacts":10,"locations":27,"responsibleParty":41,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":10,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":63,"overallStatus":70,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"University of Colorado, Denver","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Adolescents",null,"Adolescents and young adults with Turner syndrome will undergo studies of cardiometabolism, fitness, quality of life questionnaires, and a brief interview.",[13],"Other: No intervention",{"label":15,"type":10,"description":16,"interventionNames":17},"Parents","One parent of a participant will complete parent-report quality of life questionnaires and a brief interview.",[13],[19],{"type":6,"name":20,"description":20,"armGroupLabels":21,"otherNames":10},"No intervention",[9,15],[23],{"name":24,"affiliation":25,"role":26},"Shanlee Davis, MD, MS","University of Colroado","PRINCIPAL_INVESTIGATOR",[28],{"facility":29,"status":10,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":10},"Children's Hospital Colorado","Aurora","Colorado","80045","United States","US",{"type":36,"coordinates":37},"Point",[38,39],-104.83192,39.72943,{"lat":39,"lon":38},{"type":42,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100299682","health-fitness-and-quality-of-life-in-adolescent-girls-with-turner-syndrome-100299682",false,"NCT03181230","Health, Fitness, and Quality of Life in Adolescent Girls With Turner Syndrome","Pilot Study of Health, Fitness, and Quality of Life in Adolescent Girls With Turner Syndrome","Inclusion Criteria:\n\n* Female\n* Age 12-21 years\n* 45,XO karyotype in \\>50% of cells tested with a diagnosis of Turner syndrome (TS)\n* Tanner stage 2-5 for breast development\n\nExclusion Criteria:\n\n* Growth hormone treatment within the past 3 months\n* Diagnosis of type 1 or type 2 diabetes\n* Untreated hypertension with blood pressure \\> 99%ile for sex, age and height or \\>140\u002F90\n* Weight \\> 300 lbs\n* Height \\\u003C 54\"\n* Aortic sinus of Valsalva or ascending aorta z-score \\> 2\n* Other cognitive, psychiatric, or physical impairment resulting in inability to tolerate the study procedures, including vigorous exercise\n* Pregnancy","FEMALE","12 Years","21 Years",{"count":54,"type":55},21,"ACTUAL","OBSERVATIONAL","This study plans to learn more about how the energy system works in girls with Turner syndrome. This is important to know so that the investigators understand how Turner syndrome relates to diseases such as diabetes, extra weight gain, heart disease and liver disease, and how this impacts day to day life.",[59,60,61,62],"Turner Syndrome","Turner Syndrome Mosaicism, 45, X\u002F46, XX or XY","Turner Syndrome Mosaicism 46,X,I(X)(Q10)\u002F45,X","Turner Syndrome Karyotype 46,X With Abnormal Sex Chromosome , Except I(Xq)",[64,65,66,67,68,69],"Turner syndrome","45,XO","body composition","cardiometabolism","quality of life","fitness","COMPLETED","2021-04-29",{"date":73,"type":55},"2021-05-03",{"date":75,"type":55},"2017-05-26",{"date":77,"type":55},"2018-12-31",{"name":5,"class":6},1]