[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100151825":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":10,"locations":20,"responsibleParty":34,"collaborators":10,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":39,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":10,"studyType":51,"phases":10,"briefSummary":52,"conditions":53,"keywords":10,"overallStatus":57,"whyStopped":10,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},{"fullName":5,"class":6},"University of Mississippi Medical Center","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Hydralazine",null,"This group will receive administration of the antihypertensive Hydralazine for the attempted control of their blood pressure and stabilization of their hemodynamic state.",{"label":13,"type":10,"description":14,"interventionNames":10},"Labetalol","This group will receive administration of the antihypertensive Labetalol for the attempted control of their blood pressure and stabilization of their hemodynamic state.",[16],{"name":17,"affiliation":18,"role":19},"James N Martin, MD","SOM-Obstetrics & Gynecology","PRINCIPAL_INVESTIGATOR",[21],{"facility":22,"status":10,"city":23,"state":24,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":10},"Wiser Hospital for Women and Infants at the University of Mississippi Medical Center","Jackson","Mississippi","39216","United States","US",{"type":29,"coordinates":30},"Point",[31,32],-90.18481,32.29876,{"lat":32,"lon":31},{"type":19,"investigatorFullName":35,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"James Martin","Professor, Ob-Gyn","100151825","impedance-cardiographic-icg-assessment-of-pregnant-women-with-severe-hypertension-to-assess-impact-of-standard-therapy-100151825",false,"NCT01248169","Impedance Cardiographic (ICG) Assessment of Pregnant Women With Severe Hypertension to Assess Impact of Standard Therapy","Impedance Cardiographic Assessment of Gravidas With Severe Hypertension (ICASH)to Assess Impact of Standard Therapy on Hemodynamic Parameters - A Pilot Study","ICASH","Inclusion Criteria:\n\n* Nulliparous or parous patients with severe hypertension\n* Singleton gestation\n* Gestational age greater than 20 weeks\n\nExclusion Criteria:\n\n* Multiple gestation\n* Gestational age less than 20 weeks","FEMALE","18 Years","45 Years",{"count":49,"type":50},30,"ACTUAL","OBSERVATIONAL","The utilization of external cardiohemodynamic patient assessment, applying non-invasive stick-on contact patches to the mother's neck on either side and chest wall on either side, enables the practitioner to have information about the patient's cardiac function and vascular status beyond simply blood pressure and pulse. This information, once collected, should open the practitioner's eyes to better assess the patient's disease status and her response to therapy. We will use this information to compare the effectiveness of the two standard medications used for treatment of maternal high blood pressure.",[54,55,56],"Pregnancy; Proteinuria, With Hypertension (Severe Pre-eclampsia)","Delivery; Proteinuria, With Gestational Hypertension (Pre-eclampsia, Severe)","Pregnancy; Hypertension, Gestational Hypertension, With Albuminuria (Severe Pre-eclampsia)","COMPLETED","2013-12-11",{"date":60,"type":61},"2013-12-12","ESTIMATED",{"date":63,"type":10},"2009-12",{"date":65,"type":50},"2013-11",{"name":5,"class":6},1]