[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100347871":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":27,"responsibleParty":50,"collaborators":52,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":10,"enrollmentInfo":65,"targetDuration":10,"studyType":68,"phases":10,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":78,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"\"No touch\" group:",null,"Patients with left sided colic adenocarcinoma who underwent left colectomy with an early ligation of mesenteric vessels",{"label":13,"type":10,"description":14,"interventionNames":10},"\"Mobilisation first\" group","patients with right colic adenocarcinoma who underwent right colectomy with early mobilisation of the tumor followed by the ligation of the vessels.",[16],{"name":17,"affiliation":5,"role":18},"Yann Parc, PU-PH","PRINCIPAL_INVESTIGATOR",[20,24],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","0149282540","yann.parc@aphp.fr",{"name":25,"role":21,"phone":22,"phoneExt":10,"email":26},"Jeremie Lefevre, MD, PhD","jeremie.lefevre@aphp.fr",[28],{"facility":29,"status":30,"city":31,"state":10,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Department of Digestive Surgery, Hôpital Saint-Antoine","RECRUITING","Paris","75012","France","FR",{"type":36,"coordinates":37},"Point",[38,39],2.3488,48.85341,{"lat":39,"lon":38},[42,46],{"name":43,"role":21,"phone":44,"phoneExt":10,"email":45},"Yann PARC, PUPH, MD","00 33 1 49 28 25 47","yann.parc@sat.aphp.fr",{"name":47,"role":21,"phone":48,"phoneExt":10,"email":49},"Hélène HERMAND, Degree","00 33 1 49 28 66 80","alex.duval@inserm.fr",{"type":51,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[53],{"name":54,"class":55},"Institut National de la Santé Et de la Recherche Médicale, France","OTHER_GOV","100347871","influence-of-the-surgical-technique-used-for-colectomies-on-the-concentration-of-circulating-tumor-dna-and-the-presence-of-circulating-tumor-cells-comparison-of-the-no-touch-technic-with-either-first-clamping-of-the-mesenteric-vessels-or-first-mobilization-of-the-tumor-followed-by-clamping-100347871",false,"NCT03809403","Influence of the Surgical Technique Used for Colectomies on the Concentration of Circulating Tumor DNA and the Presence of Circulating Tumor Cells: Comparison of the \"no Touch\" Technic With Either First Clamping of the Mesenteric Vessels or First Mobilization of the Tumor Followed by Clamping.","ADNCHIR","Inclusion Criteria:\n\n* men and women, aged over18 years old and more\n* colectomy for localized colon adenocarcinoma\n* Adenocarcinoma of the colon stage 1,2,3\n* Patient having signed the consent\n\nExclusion Criteria:\n\n* carcinomatosis\n* metastatic tumor\n* pregnancy and breast feeding","ALL","18 Years",{"count":66,"type":67},40,"ESTIMATED","OBSERVATIONAL","Colectomy is the most commonly used therapeutic approach for the treatment of non-metastatic colorectal cancer. This approach is generally very effective however the rate of recurrence and the appearance of metachronous metastasis remains a major problem in the postoperative period. One of the hypothesis that can explain this tumor progression is the dissemination of tumor cells at the time of tumor mobilization. In this work, we wish to verify this hypothesis by comparing two surgical technics used in our department for left or right colectomies: respectively either first section of the mesenteric vessels followed by the mobilization of the tumor or first mobilization of the tumor followed by the section of the mesenteric vessels. To evaluate the dissemination, we will study two disseminations markers that have shown their prognostic value: i) circulating tumor cells (which represent a direct marker of dissemination) and ii) tumor circulating DNA (which is an indirect marker) but has the advantage of being more representative of all tumor clones and therefore the tumor burden released into the blood at the time of surgery).",[71],"Colorectal Cancer",[73,74,75,76,77],"Colorectal cancer","Surgical Technic","No touch technic","Circulating Tumor DNA","Circulating Tumor Cells","UNKNOWN","2019-03-12",{"date":81,"type":82},"2019-03-14","ACTUAL",{"date":84,"type":82},"2019-02-05",{"date":86,"type":67},"2019-08",{"name":5,"class":6},1]