[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100331408":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":10,"locations":45,"responsibleParty":51,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":10,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":73,"overallStatus":79,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Hospital Italiano de Buenos Aires","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Hyper-reduced liver recipients.",null,"Low-weight children who underwent live donor liver transplantation with ultrasound-guided in situ left lateral segment graft hyper-reduction.",[13],"Procedure: Liver transplantation with hyper-reduced grafts",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Liver transplantation with hyper-reduced grafts","Live donor liver transplantation using non-anatomical in-situ ultrasound-guided reduction of left lateral segments with preparation of a graft that is larger than a monosegment, but smaller than Segments 2 and 3.",[9],[21,25,28,30,33,35,38,40,42],{"name":22,"affiliation":23,"role":24},"Micaela Raices, Physician","Department of General Surgery, Division of HPB Surgery and Liver Transplant Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.","PRINCIPAL_INVESTIGATOR",{"name":26,"affiliation":23,"role":27},"Matias E Czerwonko, Physician","STUDY_CHAIR",{"name":29,"affiliation":23,"role":27},"Victoria Ardiles, Physician",{"name":31,"affiliation":32,"role":27},"Gustavo Boldrini, Physician","Department of Pediatrics, Division of Pediatric Gastroenterology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.",{"name":34,"affiliation":32,"role":27},"Daniel D'Agostino, Physician",{"name":36,"affiliation":37,"role":27},"José Marcó del Pont, Physician","Department of Pediatrics, Division of Pediatric Infectious Diseases, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.",{"name":39,"affiliation":23,"role":27},"Juan Pekolj, Doctor",{"name":41,"affiliation":23,"role":27},"Eduardo de Santibañes, Doctor",{"name":43,"affiliation":23,"role":44},"Martin de Santibañes, Physician","STUDY_DIRECTOR",[46],{"facility":5,"status":10,"city":47,"state":10,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":10,"geoPoint":10,"contacts":10},"Capital Federal","C1100AAF","Argentina","AR",{"type":24,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"MICAELA RAICES","Principal Investigator","100331408","outcomes-of-liver-transplantation-in-low-weight-children-after-reducing-the-lateral-segment-of-a-living-donor-adapting-the-shape-and-size-of-the-graft-to-the-needs-of-the-recipient-100331408",false,"NCT03594864","Outcomes of Liver Transplantation in Low Weight Children After Reducing the Lateral Segment of a Living Donor, Adapting the Shape and Size of the Graft to the Needs of the Recipient","Short and Long-term Outcomes After Transplantation With Hyper-reduced Liver Grafts in Low-Weight Pediatric Recipients","Inclusion Criteria:\n\n* \\\u003C or = 17 years old.\n* Having undergone live donor liver transplantation.\n* Having received hyper-reduced liver grafts\n* At the Liver Transplantation Unit of the Hospital Italiano de Buenos Aires\n* Between June 1997 and April 2018\n\nExclusion Criteria:\n\n* \\> 17 years old.\n* Cadaveric liver transplant\n* Whole liver grafts.","ALL","5 Months","17 Years",{"count":65,"type":66},58,"ACTUAL","OBSERVATIONAL","The shortage of organs has always been a problem in pediatric liver transplants due to the lack of donors with an adequate size. Different techniques of hepatic reduction have been described that allow to use larger organs in the pediatric population. However, in these techniques the maximum reduction achieved by segments 2 and 3 is excessive for low-weight children. Since 1997 the liver transplantation group at Hospital Italiano de Buenos Aires has developed and practiced a technique called hepatic hyper-reduction, which consists in reducing the lateral segment of a living donor, adapting the shape and size of the graft to the needs of the recipient. The investigators have performed approximately 50 pediatric liver transplants with live donors in low weight children in whom the hyper-reduction technique has been applied. The aim of the present study is to describe postoperative morbidity and mortality and analyze overall and graft survival.",[70,71,72],"Liver Transplantation","Low-weight Children","Hyper-reduced Liver Grafts",[74,75,76,77,78],"Liver","Transplantation","Hyper-reduction","Graft survival","Overall survival","COMPLETED","2018-07-19",{"date":82,"type":66},"2018-07-20",{"date":84,"type":66},"2018-04-21",{"date":86,"type":66},"2018-06-03",{"name":5,"class":6},1]