[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100279797":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":19,"locations":24,"responsibleParty":35,"collaborators":19,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":19,"eligibilityCriteria":44,"healthyVolunteers":40,"sex":45,"minAge":46,"maxAge":19,"enrollmentInfo":47,"targetDuration":19,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":61,"whyStopped":19,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Institute for Clinical and Experimental Medicine","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"pCLE vs. biopsies with histopathology","OTHER","The investigators will compare diagnostic accuracy and sensitivity of pCLE with standard biopsies in patients with esophageal and gastric lesions and in patients after completed endoscopic treatment of BORN.\n\nAll samples taken by biopsies will be correlated with the images taken by pCLE in the detection of lesions, intestinal metaplasia, dysplasia and buried glands.",[13],"Other: Biopsies with histopathology",[15],{"type":10,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Biopsies with histopathology","All samples taken by biopsies will be correlated with the images taken by CLE.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Jan Martinek, MD. PhD.","PRINCIPAL_INVESTIGATOR",[25],{"facility":5,"status":19,"city":26,"state":26,"zip":27,"country":28,"countryCode":19,"cosmosGeoPoint":29,"geoPoint":34,"contacts":19},"Prague","14021","Czechia",{"type":30,"coordinates":31},"Point",[32,33],14.42076,50.08804,{"lat":33,"lon":32},{"type":23,"investigatorFullName":36,"investigatorTitle":37,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Doc. (Ass. prof.) Jan Martinek, MD, PhD, AGAF","Ass. Prof. MD. Ph.D. AGAF","100279797","pcle-in-the-detection-of-esophageal-and-gastric-lesions-and-intestinal-metaplasia-or-dysplasia-in-patients-after-endoscopic-treatment-of-born-100279797",false,"NCT02922049","pCLE in the Detection of Esophageal and Gastric Lesions and Intestinal Metaplasia or Dysplasia in Patients After Endoscopic Treatment of BORN","Probe-based Confocal Laser Endomicroscopy in Accurate Histopathologic Diagnosis of Neoplastic Gastrointestinal Lesion","Inclusion Criteria:\n\n* age \\> 18\n* macroscopic lesion of esophagus or stomach (Project A)\n* pts after ER\u002FESD\u002FRFA for BORN (Project B)\n* eradication of BORN and Barrett's esophagus macro- and microscopically (Project B)\n* sign agreement with study\n\nExclusion Criteria:\n\n* macroscopic persistence of Barrett's esophagus (e.g. tongues)\n* esophageal varices\n* treatment with anticoagulants\n* allergy to fluorescein\n* polyvalent allergy\n* pregnancy","ALL","18 Years",{"count":48,"type":49},67,"ACTUAL","INTERVENTIONAL",[52],"NA","To assess diagnostic accuracy and clinical effectiveness including cost-effectiveness analysis of pCLE in patients after finishing the endoscopic treatment of BORN in detecting persistent\u002Frecurrent IM, recurrent neoplasia and buried glands.",[55],"Barrett's Esophagus",[57,58,59,60],"Probe Based Confocal Laser Endomicroscopy (pCLE)","Barrett's esophagus","BORN","Intestinal metaplasia","COMPLETED","2020-02-15",{"date":64,"type":49},"2020-02-18",{"date":66,"type":49},"2016-04",{"date":68,"type":49},"2020-01",{"name":5,"class":6},1]