[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100469201":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":44,"centralContacts":11,"locations":47,"responsibleParty":61,"collaborators":11,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":11,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":11,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":86,"whyStopped":11,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Bristol-Myers Squibb","INDUSTRY",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Part 1","EXPERIMENTAL",null,[13,14],"Drug: CC-92480","Drug: Rifampin",{"label":16,"type":10,"description":11,"interventionNames":17},"Part 2",[13,18],"Drug: Itraconazole",{"label":20,"type":10,"description":11,"interventionNames":21},"Part 3",[13,22,23],"Drug: Digoxin","Drug: Rosuvastatin",[25,32,35,38,41],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DRUG","CC-92480","Specified dose on specified days",[9,16,20],[31],"BMS-986348",{"type":26,"name":33,"description":28,"armGroupLabels":34,"otherNames":11},"Rifampin",[9],{"type":26,"name":36,"description":28,"armGroupLabels":37,"otherNames":11},"Itraconazole",[16],{"type":26,"name":39,"description":28,"armGroupLabels":40,"otherNames":11},"Digoxin",[20],{"type":26,"name":42,"description":28,"armGroupLabels":43,"otherNames":11},"Rosuvastatin",[20],[45],{"name":5,"affiliation":5,"role":46},"STUDY_DIRECTOR",[48],{"facility":49,"status":11,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":11},"Covance Clinical Research Unit - Dallas","Dallas","Texas","75247-4968","United States","US",{"type":56,"coordinates":57},"Point",[58,59],-96.80667,32.78306,{"lat":59,"lon":58},{"type":62,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100469201","phase-1-a-study-to-assess-the-drug-levels-of-cc-92480-after-coadministration-with-rifampin-and-itraconazole-and-the-drug-levels-of-digoxin-and-rosuvastatin-after-coadministration-with-cc-92480-in-healthy-participants-100469201",false,"NCT05389722","A Study to Assess the Drug Levels of CC-92480 After Coadministration With Rifampin and Itraconazole, and the Drug Levels of Digoxin and Rosuvastatin After Coadministration With CC-92480 in Healthy Participants","A Phase 1, Parallel-group, 3-part, 2-period, Fixed-sequence, Crossover, Open-label, Nonrandomized, Drug-drug Interaction Study to Assess the Pharmacokinetics of CC-92480 (BMS-986348) After Coadministration With Rifampin and Itraconazole, and Pharmacokinetics of Digoxin and Rosuvastatin After Coadministration With CC-92480 in Healthy Participants","Inclusion Criteria:\n\n* Must have a body mass index between 18 and 33 kg\u002Fm2 (inclusive)\n* Adult female of nonchildbearing potential or male, any race or ethnicity, and in good health as determined by the medical history, physical exam, vital signs, 12-lead electrocardiogram, and clinical laboratory assessments\n\nExclusion Criteria:\n\n* Any surgical or medical condition possibly affecting drug absorption, distribution, metabolism, and excretion\n* Any major surgery within 4 weeks of the first dose administration\n* History of drug abuse within 2 years of the first dose administration\n\nOther protocol-defined inclusion\u002Fexclusion criteria apply",true,"ALL","18 Years","55 Years",{"count":75,"type":76},24,"ACTUAL","INTERVENTIONAL",[79],"PHASE1","The purpose of this study is to evaluate the drug levels of CC-92480 after coadministration with rifampin and itraconazole and the drug levels of digoxin and rosuvastatin after coadministration with CC-92480 in healthy participants.",[82],"Healthy Volunteers",[27,84,85],"Healthy Volunteer","Pharmacokinetic","COMPLETED","2023-04-18",{"date":89,"type":76},"2023-04-19",{"date":91,"type":76},"2022-06-09",{"date":93,"type":76},"2022-11-12",{"name":5,"class":6},1]