[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100132326":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":23,"locations":23,"responsibleParty":33,"collaborators":23,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":23,"eligibilityCriteria":41,"healthyVolunteers":42,"sex":43,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":23,"studyType":49,"phases":50,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":57,"whyStopped":23,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":23},{"fullName":5,"class":6},"Boryung Pharmaceutical Co., Ltd","INDUSTRY",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Group B","OTHER","Atorvastatin (7 days) → Fimasartan + Atorvastatin (7 days)",[13,14],"Drug: Atorvastatin","Drug: Fimasartan",{"label":16,"type":10,"description":17,"interventionNames":18},"Group A","Fimasartan (7 days) → Fimasartan + Atorvastatin (7 days)",[13,14],[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":23},"DRUG","Atorvastatin",null,[16,9],{"type":21,"name":26,"description":23,"armGroupLabels":27,"otherNames":23},"Fimasartan",[16,9],[29],{"name":30,"affiliation":31,"role":32},"Kyung-Sang Yu, MD","Seoul National University Hospital","STUDY_CHAIR",{"type":23,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":34,"oldOrganization":5},"Choi, Director","100132326","phase-1-a-study-to-evaluate-the-effect-of-atorvastatin-on-the-pharmacokinetics-of-fimasartan-in-healthy-male-volunteers-100132326",false,"NCT00991705","A Study to Evaluate the Effect of Atorvastatin on the Pharmacokinetics of Fimasartan in Healthy Male Volunteers","An Open-label, Two-treatment, Two-period, Two-sequence, Crossover Study to Evaluate the Effect of Atorvastatin on the Pharmacokinetics of Fimasartan in Healthy Male Volunteers","Inclusion Criteria:\n\n* age: 20 - 45 years\n* sex: male\n* body weight: greater than 55 kg\n* written informed consent\n\nExclusion Criteria:\n\n* known allergy to Fimasartan and atorvastatin\n* existing cardiac or hematological diseases\n* existing hepatic and renal diseases\n* existing gastrointestinal diseases\n* acute or chronic diseases which could affect drug absorption or metabolism history of any serious psychological disorder\n* positive drug or alcohol screening\n* smokers of 10 or more cigarettes per day 3 month ago\n* participation in a clinical trial during the last 2 months prior to the start of the study",true,"MALE","20 Years","45 Years",{"count":47,"type":48},28,"ACTUAL","INTERVENTIONAL",[51],"PHASE1","The purpose of this study is to evaluate the effect of atorvastatin on the pharmacokinetics of fimasartan.",[54],"Essential Hypertension",[56],"Fimasartan, Atorvastatin","COMPLETED","2009-10-07",{"date":60,"type":61},"2009-10-08","ESTIMATED",{"date":63,"type":23},"2009-07",{"date":65,"type":48},"2009-09",{"name":5,"class":6}]