[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100243118":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":41,"centralContacts":11,"locations":45,"responsibleParty":921,"collaborators":11,"id":923,"slug":924,"hasResults":925,"nctId":926,"briefTitle":927,"officialTitle":928,"acronym":11,"eligibilityCriteria":929,"healthyVolunteers":930,"sex":931,"minAge":932,"maxAge":933,"enrollmentInfo":934,"targetDuration":11,"studyType":937,"phases":938,"briefSummary":940,"conditions":941,"keywords":11,"overallStatus":944,"whyStopped":11,"lastUpdateSubmitDate":945,"lastUpdatePostDateStruct":946,"startDateStruct":948,"completionDateStruct":950,"leadSponsor":952,"locationsCount":953},{"fullName":5,"class":6},"Novo Nordisk A\u002FS","INDUSTRY",[8,15,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"NNC0114-0006 + Liraglutide","EXPERIMENTAL",null,[13,14],"Drug: NNC0114-0006","Drug: liraglutide",{"label":16,"type":10,"description":11,"interventionNames":17},"NNC0114-0006 + Placebo",[13,18],"Drug: placebo",{"label":20,"type":21,"description":11,"interventionNames":22},"Liraglutide + Placebo","ACTIVE_COMPARATOR",[14,18],{"label":24,"type":25,"description":11,"interventionNames":26},"Placebo","PLACEBO_COMPARATOR",[18],[28,33,37],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":11},"DRUG","NNC0114-0006","NNC0114-0006 12 mg\u002Fkg administered i.v (intravenously) every 6 weeks. Subjects will continue their pre-trial insulin treatment",[9,16],{"type":29,"name":34,"description":35,"armGroupLabels":36,"otherNames":11},"liraglutide","Liraglutide 1.8 mg administered s.c. (subcutaneously) daily. Subjects will continue their pre-trial insulin treatment",[20,9],{"type":29,"name":38,"description":39,"armGroupLabels":40,"otherNames":11},"placebo","Placebo administered s.c (subcutaneously) or i.v ( intravenously). Subjects will continue their pre-trial insulin treatment",[20,16,24],[42],{"name":43,"affiliation":5,"role":44},"Global Clinical Registry (GCR, 1452)","STUDY_DIRECTOR",[46,59,67,76,85,93,102,111,120,129,138,147,156,164,174,182,190,198,203,213,221,229,240,249,258,267,276,284,293,301,304,312,322,330,338,348,356,364,374,379,387,397,405,413,421,431,439,447,455,465,473,483,488,496,504,514,522,530,538,546,554,564,572,580,588,596,601,609,617,625,633,638,646,654,662,672,680,690,698,706,714,722,730,735,743,753,761,769,777,787,792,797,802,807,815,823,833,841,849,857,865,868,876,881,889,897,905,913],{"facility":47,"status":11,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":11},"Novo Nordisk Investigational Site","La Jolla","California","92037","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-117.2742,32.84727,{"lat":57,"lon":56},{"facility":47,"status":11,"city":60,"state":49,"zip":61,"country":51,"countryCode":52,"cosmosGeoPoint":62,"geoPoint":66,"contacts":11},"Northridge","91325",{"type":54,"coordinates":63},[64,65],-118.53675,34.22834,{"lat":65,"lon":64},{"facility":47,"status":11,"city":68,"state":69,"zip":70,"country":51,"countryCode":52,"cosmosGeoPoint":71,"geoPoint":75,"contacts":11},"Aurora","Colorado","80045",{"type":54,"coordinates":72},[73,74],-104.83192,39.72943,{"lat":74,"lon":73},{"facility":47,"status":11,"city":77,"state":78,"zip":79,"country":51,"countryCode":52,"cosmosGeoPoint":80,"geoPoint":84,"contacts":11},"Miami","Florida","33136",{"type":54,"coordinates":81},[82,83],-80.19366,25.77427,{"lat":83,"lon":82},{"facility":47,"status":11,"city":86,"state":78,"zip":87,"country":51,"countryCode":52,"cosmosGeoPoint":88,"geoPoint":92,"contacts":11},"Orlando","32804",{"type":54,"coordinates":89},[90,91],-81.37924,28.53834,{"lat":91,"lon":90},{"facility":47,"status":11,"city":94,"state":95,"zip":96,"country":51,"countryCode":52,"cosmosGeoPoint":97,"geoPoint":101,"contacts":11},"Atlanta","Georgia","30318",{"type":54,"coordinates":98},[99,100],-84.38798,33.749,{"lat":100,"lon":99},{"facility":47,"status":11,"city":103,"state":104,"zip":105,"country":51,"countryCode":52,"cosmosGeoPoint":106,"geoPoint":110,"contacts":11},"Lexington","Kentucky","40503",{"type":54,"coordinates":107},[108,109],-84.47772,37.98869,{"lat":109,"lon":108},{"facility":47,"status":11,"city":112,"state":113,"zip":114,"country":51,"countryCode":52,"cosmosGeoPoint":115,"geoPoint":119,"contacts":11},"Las Vegas","Nevada","89128",{"type":54,"coordinates":116},[117,118],-115.13722,36.17497,{"lat":118,"lon":117},{"facility":47,"status":11,"city":121,"state":122,"zip":123,"country":51,"countryCode":52,"cosmosGeoPoint":124,"geoPoint":128,"contacts":11},"Teaneck","New Jersey","07666",{"type":54,"coordinates":125},[126,127],-74.01597,40.8976,{"lat":127,"lon":126},{"facility":47,"status":11,"city":130,"state":131,"zip":132,"country":51,"countryCode":52,"cosmosGeoPoint":133,"geoPoint":137,"contacts":11},"Chapel Hill","North Carolina","27517",{"type":54,"coordinates":134},[135,136],-79.05584,35.9132,{"lat":136,"lon":135},{"facility":47,"status":11,"city":139,"state":140,"zip":141,"country":51,"countryCode":52,"cosmosGeoPoint":142,"geoPoint":146,"contacts":11},"Nashville","Tennessee","37203",{"type":54,"coordinates":143},[144,145],-86.78444,36.16589,{"lat":145,"lon":144},{"facility":47,"status":11,"city":148,"state":149,"zip":150,"country":51,"countryCode":52,"cosmosGeoPoint":151,"geoPoint":155,"contacts":11},"Houston","Texas","77079",{"type":54,"coordinates":152},[153,154],-95.36327,29.76328,{"lat":154,"lon":153},{"facility":47,"status":11,"city":157,"state":149,"zip":158,"country":51,"countryCode":52,"cosmosGeoPoint":159,"geoPoint":163,"contacts":11},"Mesquite","75149",{"type":54,"coordinates":160},[161,162],-96.59916,32.7668,{"lat":162,"lon":161},{"facility":47,"status":11,"city":165,"state":11,"zip":166,"country":167,"countryCode":168,"cosmosGeoPoint":169,"geoPoint":173,"contacts":11},"Graz","8036","Austria","AT",{"type":54,"coordinates":170},[171,172],15.44197,47.06733,{"lat":172,"lon":171},{"facility":47,"status":11,"city":175,"state":11,"zip":176,"country":167,"countryCode":168,"cosmosGeoPoint":177,"geoPoint":181,"contacts":11},"Innsbruck","6020",{"type":54,"coordinates":178},[179,180],11.39454,47.26266,{"lat":180,"lon":179},{"facility":47,"status":11,"city":183,"state":11,"zip":184,"country":167,"countryCode":168,"cosmosGeoPoint":185,"geoPoint":189,"contacts":11},"Salzburg","5020",{"type":54,"coordinates":186},[187,188],13.04399,47.79941,{"lat":188,"lon":187},{"facility":47,"status":11,"city":191,"state":11,"zip":192,"country":167,"countryCode":168,"cosmosGeoPoint":193,"geoPoint":197,"contacts":11},"Vienna","1030",{"type":54,"coordinates":194},[195,196],16.37208,48.20849,{"lat":196,"lon":195},{"facility":47,"status":11,"city":191,"state":11,"zip":199,"country":167,"countryCode":168,"cosmosGeoPoint":200,"geoPoint":202,"contacts":11},"1130",{"type":54,"coordinates":201},[195,196],{"lat":196,"lon":195},{"facility":47,"status":11,"city":204,"state":11,"zip":205,"country":206,"countryCode":207,"cosmosGeoPoint":208,"geoPoint":212,"contacts":11},"Brussels","1090","Belgium","BE",{"type":54,"coordinates":209},[210,211],4.34878,50.85045,{"lat":211,"lon":210},{"facility":47,"status":11,"city":214,"state":11,"zip":215,"country":206,"countryCode":207,"cosmosGeoPoint":216,"geoPoint":220,"contacts":11},"Edegem","2650",{"type":54,"coordinates":217},[218,219],4.44504,51.15662,{"lat":219,"lon":218},{"facility":47,"status":11,"city":222,"state":11,"zip":223,"country":206,"countryCode":207,"cosmosGeoPoint":224,"geoPoint":228,"contacts":11},"Leuven","3000",{"type":54,"coordinates":225},[226,227],4.70093,50.87959,{"lat":227,"lon":226},{"facility":47,"status":11,"city":230,"state":231,"zip":232,"country":233,"countryCode":234,"cosmosGeoPoint":235,"geoPoint":239,"contacts":11},"Edmonton","Alberta","T6G 2E1","Canada","CA",{"type":54,"coordinates":236},[237,238],-113.46871,53.55014,{"lat":238,"lon":237},{"facility":47,"status":11,"city":241,"state":242,"zip":243,"country":233,"countryCode":234,"cosmosGeoPoint":244,"geoPoint":248,"contacts":11},"Vancouver","British Columbia","V5Z 1M9",{"type":54,"coordinates":245},[246,247],-123.11934,49.24966,{"lat":247,"lon":246},{"facility":47,"status":11,"city":250,"state":251,"zip":252,"country":233,"countryCode":234,"cosmosGeoPoint":253,"geoPoint":257,"contacts":11},"Winnipeg","Manitoba","R3E 3P4",{"type":54,"coordinates":254},[255,256],-97.14704,49.8844,{"lat":256,"lon":255},{"facility":47,"status":11,"city":259,"state":260,"zip":261,"country":233,"countryCode":234,"cosmosGeoPoint":262,"geoPoint":266,"contacts":11},"Halifax","Nova Scotia","B3H 2Y9",{"type":54,"coordinates":263},[264,265],-63.57688,44.64269,{"lat":265,"lon":264},{"facility":47,"status":11,"city":268,"state":269,"zip":270,"country":233,"countryCode":234,"cosmosGeoPoint":271,"geoPoint":275,"contacts":11},"Kingston","Ontario","K7L 2V7",{"type":54,"coordinates":272},[273,274],-76.48098,44.22976,{"lat":274,"lon":273},{"facility":47,"status":11,"city":277,"state":269,"zip":278,"country":233,"countryCode":234,"cosmosGeoPoint":279,"geoPoint":283,"contacts":11},"Toronto","M4G 3E8",{"type":54,"coordinates":280},[281,282],-79.39864,43.70643,{"lat":282,"lon":281},{"facility":47,"status":11,"city":285,"state":286,"zip":287,"country":233,"countryCode":234,"cosmosGeoPoint":288,"geoPoint":292,"contacts":11},"Laval","Quebec","H7T 2P5",{"type":54,"coordinates":289},[290,291],-73.692,45.56995,{"lat":291,"lon":290},{"facility":47,"status":11,"city":294,"state":286,"zip":295,"country":233,"countryCode":234,"cosmosGeoPoint":296,"geoPoint":300,"contacts":11},"Montreal","H4A 3T2",{"type":54,"coordinates":297},[298,299],-73.58781,45.50884,{"lat":299,"lon":298},{"facility":47,"status":11,"city":302,"state":286,"zip":303,"country":233,"countryCode":234,"cosmosGeoPoint":11,"geoPoint":11,"contacts":11},"PQ","G1L 3L5",{"facility":47,"status":11,"city":305,"state":286,"zip":306,"country":233,"countryCode":234,"cosmosGeoPoint":307,"geoPoint":311,"contacts":11},"Sherbrooke","J1H 5N4",{"type":54,"coordinates":308},[309,310],-71.89908,45.40008,{"lat":310,"lon":309},{"facility":47,"status":11,"city":313,"state":11,"zip":314,"country":315,"countryCode":316,"cosmosGeoPoint":317,"geoPoint":321,"contacts":11},"Aarhus N","8200","Denmark","DK",{"type":54,"coordinates":318},[319,320],10.17317,56.20367,{"lat":320,"lon":319},{"facility":47,"status":11,"city":323,"state":11,"zip":324,"country":315,"countryCode":316,"cosmosGeoPoint":325,"geoPoint":329,"contacts":11},"Esbjerg","6700",{"type":54,"coordinates":326},[327,328],8.45187,55.47028,{"lat":328,"lon":327},{"facility":47,"status":11,"city":331,"state":11,"zip":332,"country":315,"countryCode":316,"cosmosGeoPoint":333,"geoPoint":337,"contacts":11},"Hellerup","2900",{"type":54,"coordinates":334},[335,336],12.57093,55.73204,{"lat":336,"lon":335},{"facility":47,"status":11,"city":339,"state":11,"zip":340,"country":341,"countryCode":342,"cosmosGeoPoint":343,"geoPoint":347,"contacts":11},"Helsinki","00290","Finland","FI",{"type":54,"coordinates":344},[345,346],24.93545,60.16952,{"lat":346,"lon":345},{"facility":47,"status":11,"city":349,"state":11,"zip":350,"country":341,"countryCode":342,"cosmosGeoPoint":351,"geoPoint":355,"contacts":11},"Oulu","90220",{"type":54,"coordinates":352},[353,354],25.46816,65.01236,{"lat":354,"lon":353},{"facility":47,"status":11,"city":357,"state":11,"zip":358,"country":341,"countryCode":342,"cosmosGeoPoint":359,"geoPoint":363,"contacts":11},"Tampere","33520",{"type":54,"coordinates":360},[361,362],23.78712,61.49911,{"lat":362,"lon":361},{"facility":47,"status":11,"city":365,"state":11,"zip":366,"country":367,"countryCode":368,"cosmosGeoPoint":369,"geoPoint":373,"contacts":11},"Dublin","DUBLIN 15","Ireland","IE",{"type":54,"coordinates":370},[371,372],-6.24889,53.33306,{"lat":372,"lon":371},{"facility":47,"status":11,"city":365,"state":11,"zip":375,"country":367,"countryCode":368,"cosmosGeoPoint":376,"geoPoint":378,"contacts":11},"DUBLIN 4",{"type":54,"coordinates":377},[371,372],{"lat":372,"lon":371},{"facility":47,"status":11,"city":380,"state":11,"zip":381,"country":367,"countryCode":368,"cosmosGeoPoint":382,"geoPoint":386,"contacts":11},"Galway","H91 YR71",{"type":54,"coordinates":383},[384,385],-9.05095,53.27245,{"lat":385,"lon":384},{"facility":47,"status":11,"city":388,"state":11,"zip":389,"country":390,"countryCode":391,"cosmosGeoPoint":392,"geoPoint":396,"contacts":11},"Holon","58100","Israel","IL",{"type":54,"coordinates":393},[394,395],34.77918,32.01034,{"lat":395,"lon":394},{"facility":47,"status":11,"city":398,"state":11,"zip":399,"country":390,"countryCode":391,"cosmosGeoPoint":400,"geoPoint":404,"contacts":11},"Jerusalem","91120",{"type":54,"coordinates":401},[402,403],35.21633,31.76904,{"lat":403,"lon":402},{"facility":47,"status":11,"city":406,"state":11,"zip":407,"country":390,"countryCode":391,"cosmosGeoPoint":408,"geoPoint":412,"contacts":11},"Petah Tikva","49202",{"type":54,"coordinates":409},[410,411],34.88747,32.08707,{"lat":411,"lon":410},{"facility":47,"status":11,"city":414,"state":11,"zip":415,"country":390,"countryCode":391,"cosmosGeoPoint":416,"geoPoint":420,"contacts":11},"Rehovot","76100",{"type":54,"coordinates":417},[418,419],34.81199,31.89421,{"lat":419,"lon":418},{"facility":47,"status":11,"city":422,"state":11,"zip":423,"country":424,"countryCode":425,"cosmosGeoPoint":426,"geoPoint":430,"contacts":11},"Bergamo","24127","Italy","IT",{"type":54,"coordinates":427},[428,429],9.66721,45.69601,{"lat":429,"lon":428},{"facility":47,"status":11,"city":432,"state":11,"zip":433,"country":424,"countryCode":425,"cosmosGeoPoint":434,"geoPoint":438,"contacts":11},"Catanzaro","88100",{"type":54,"coordinates":435},[436,437],16.60086,38.88247,{"lat":437,"lon":436},{"facility":47,"status":11,"city":440,"state":11,"zip":441,"country":424,"countryCode":425,"cosmosGeoPoint":442,"geoPoint":446,"contacts":11},"Milan","20132",{"type":54,"coordinates":443},[444,445],12.59836,42.78235,{"lat":445,"lon":444},{"facility":47,"status":11,"city":448,"state":11,"zip":449,"country":424,"countryCode":425,"cosmosGeoPoint":450,"geoPoint":454,"contacts":11},"Siena","53100",{"type":54,"coordinates":451},[452,453],11.33064,43.31822,{"lat":453,"lon":452},{"facility":47,"status":11,"city":456,"state":11,"zip":457,"country":458,"countryCode":459,"cosmosGeoPoint":460,"geoPoint":464,"contacts":11},"Oslo","0586","Norway","NO",{"type":54,"coordinates":461},[462,463],10.74609,59.91273,{"lat":463,"lon":462},{"facility":47,"status":11,"city":466,"state":11,"zip":467,"country":458,"countryCode":459,"cosmosGeoPoint":468,"geoPoint":472,"contacts":11},"Stavanger","4011",{"type":54,"coordinates":469},[470,471],5.73332,58.97005,{"lat":471,"lon":470},{"facility":47,"status":11,"city":474,"state":11,"zip":475,"country":476,"countryCode":477,"cosmosGeoPoint":478,"geoPoint":482,"contacts":11},"Gdansk","80-214","Poland","PL",{"type":54,"coordinates":479},[480,481],18.64912,54.35227,{"lat":481,"lon":480},{"facility":47,"status":11,"city":474,"state":11,"zip":484,"country":476,"countryCode":477,"cosmosGeoPoint":485,"geoPoint":487,"contacts":11},"80-546",{"type":54,"coordinates":486},[480,481],{"lat":481,"lon":480},{"facility":47,"status":11,"city":489,"state":11,"zip":490,"country":476,"countryCode":477,"cosmosGeoPoint":491,"geoPoint":495,"contacts":11},"Warsaw","04-736",{"type":54,"coordinates":492},[493,494],21.01178,52.22977,{"lat":494,"lon":493},{"facility":47,"status":11,"city":497,"state":11,"zip":498,"country":476,"countryCode":477,"cosmosGeoPoint":499,"geoPoint":503,"contacts":11},"Zabrze","41-800",{"type":54,"coordinates":500},[501,502],18.78576,50.32492,{"lat":502,"lon":501},{"facility":47,"status":11,"city":505,"state":11,"zip":506,"country":507,"countryCode":508,"cosmosGeoPoint":509,"geoPoint":513,"contacts":11},"Almada","2805-267","Portugal","PT",{"type":54,"coordinates":510},[511,512],-9.1569,38.67902,{"lat":512,"lon":511},{"facility":47,"status":11,"city":515,"state":11,"zip":516,"country":507,"countryCode":508,"cosmosGeoPoint":517,"geoPoint":521,"contacts":11},"Amadora","2720-276",{"type":54,"coordinates":518},[519,520],-9.23083,38.75382,{"lat":520,"lon":519},{"facility":47,"status":11,"city":523,"state":11,"zip":524,"country":507,"countryCode":508,"cosmosGeoPoint":525,"geoPoint":529,"contacts":11},"Braga","4710-243",{"type":54,"coordinates":526},[527,528],-8.42311,41.5514,{"lat":528,"lon":527},{"facility":47,"status":11,"city":531,"state":11,"zip":532,"country":507,"countryCode":508,"cosmosGeoPoint":533,"geoPoint":537,"contacts":11},"Matosinhos Municipality","4464-513",{"type":54,"coordinates":534},[535,536],-8.68908,41.18207,{"lat":536,"lon":535},{"facility":47,"status":11,"city":539,"state":11,"zip":540,"country":507,"countryCode":508,"cosmosGeoPoint":541,"geoPoint":545,"contacts":11},"Porto","4200-319",{"type":54,"coordinates":542},[543,544],-8.61097,41.1485,{"lat":544,"lon":543},{"facility":47,"status":11,"city":547,"state":11,"zip":548,"country":507,"countryCode":508,"cosmosGeoPoint":549,"geoPoint":553,"contacts":11},"Viana do Castelo","4901-858",{"type":54,"coordinates":550},[551,552],-8.83287,41.69323,{"lat":552,"lon":551},{"facility":47,"status":11,"city":555,"state":11,"zip":556,"country":557,"countryCode":558,"cosmosGeoPoint":559,"geoPoint":563,"contacts":11},"Arkhangelsk","163001","Russia","RU",{"type":54,"coordinates":560},[561,562],40.55183,64.5461,{"lat":562,"lon":561},{"facility":47,"status":11,"city":565,"state":11,"zip":566,"country":557,"countryCode":558,"cosmosGeoPoint":567,"geoPoint":571,"contacts":11},"Chelyabinsk","454048",{"type":54,"coordinates":568},[569,570],61.42877,55.1611,{"lat":570,"lon":569},{"facility":47,"status":11,"city":573,"state":11,"zip":574,"country":557,"countryCode":558,"cosmosGeoPoint":575,"geoPoint":579,"contacts":11},"Dzerzhinskiy","140091",{"type":54,"coordinates":576},[577,578],37.8443,55.62868,{"lat":578,"lon":577},{"facility":47,"status":11,"city":581,"state":11,"zip":582,"country":557,"countryCode":558,"cosmosGeoPoint":583,"geoPoint":587,"contacts":11},"Kazan'","420012",{"type":54,"coordinates":584},[585,586],49.12214,55.78874,{"lat":586,"lon":585},{"facility":47,"status":11,"city":589,"state":11,"zip":590,"country":557,"countryCode":558,"cosmosGeoPoint":591,"geoPoint":595,"contacts":11},"Moscow","123423",{"type":54,"coordinates":592},[593,594],37.61781,55.75204,{"lat":594,"lon":593},{"facility":47,"status":11,"city":589,"state":11,"zip":597,"country":557,"countryCode":558,"cosmosGeoPoint":598,"geoPoint":600,"contacts":11},"125315",{"type":54,"coordinates":599},[593,594],{"lat":594,"lon":593},{"facility":47,"status":11,"city":602,"state":11,"zip":603,"country":557,"countryCode":558,"cosmosGeoPoint":604,"geoPoint":608,"contacts":11},"Novosibirsk","630091",{"type":54,"coordinates":605},[606,607],82.93175,55.02259,{"lat":607,"lon":606},{"facility":47,"status":11,"city":610,"state":11,"zip":611,"country":557,"countryCode":558,"cosmosGeoPoint":612,"geoPoint":616,"contacts":11},"Penza","440026",{"type":54,"coordinates":613},[614,615],45.01075,53.19568,{"lat":615,"lon":614},{"facility":47,"status":11,"city":618,"state":11,"zip":619,"country":557,"countryCode":558,"cosmosGeoPoint":620,"geoPoint":624,"contacts":11},"Saint Petersburg","199226",{"type":54,"coordinates":621},[622,623],30.31413,59.93863,{"lat":623,"lon":622},{"facility":47,"status":11,"city":626,"state":11,"zip":627,"country":557,"countryCode":558,"cosmosGeoPoint":628,"geoPoint":632,"contacts":11},"Saratov","410031",{"type":54,"coordinates":629},[630,631],45.9901,51.54048,{"lat":631,"lon":630},{"facility":47,"status":11,"city":626,"state":11,"zip":634,"country":557,"countryCode":558,"cosmosGeoPoint":635,"geoPoint":637,"contacts":11},"410053",{"type":54,"coordinates":636},[630,631],{"lat":631,"lon":630},{"facility":47,"status":11,"city":639,"state":11,"zip":640,"country":557,"countryCode":558,"cosmosGeoPoint":641,"geoPoint":645,"contacts":11},"Syktyvkar","167981",{"type":54,"coordinates":642},[643,644],50.8163,61.66393,{"lat":644,"lon":643},{"facility":47,"status":11,"city":647,"state":11,"zip":648,"country":557,"countryCode":558,"cosmosGeoPoint":649,"geoPoint":653,"contacts":11},"Ulyanovsk","432063",{"type":54,"coordinates":650},[651,652],48.38657,54.32824,{"lat":652,"lon":651},{"facility":47,"status":11,"city":655,"state":11,"zip":656,"country":557,"countryCode":558,"cosmosGeoPoint":657,"geoPoint":661,"contacts":11},"Yoshkar-Ola","424004",{"type":54,"coordinates":658},[659,660],47.89078,56.63877,{"lat":660,"lon":659},{"facility":47,"status":11,"city":663,"state":11,"zip":664,"country":665,"countryCode":666,"cosmosGeoPoint":667,"geoPoint":671,"contacts":11},"Belgrade","11000","Serbia","RS",{"type":54,"coordinates":668},[669,670],20.46513,44.80401,{"lat":670,"lon":669},{"facility":47,"status":11,"city":673,"state":11,"zip":674,"country":665,"countryCode":666,"cosmosGeoPoint":675,"geoPoint":679,"contacts":11},"Kragujevac","34000",{"type":54,"coordinates":676},[677,678],20.91667,44.01667,{"lat":678,"lon":677},{"facility":47,"status":11,"city":681,"state":11,"zip":682,"country":683,"countryCode":684,"cosmosGeoPoint":685,"geoPoint":689,"contacts":11},"Barcelona","08035","Spain","ES",{"type":54,"coordinates":686},[687,688],2.15899,41.38879,{"lat":688,"lon":687},{"facility":47,"status":11,"city":691,"state":11,"zip":692,"country":683,"countryCode":684,"cosmosGeoPoint":693,"geoPoint":697,"contacts":11},"Girona","17007",{"type":54,"coordinates":694},[695,696],2.82493,41.98311,{"lat":696,"lon":695},{"facility":47,"status":11,"city":699,"state":11,"zip":700,"country":683,"countryCode":684,"cosmosGeoPoint":701,"geoPoint":705,"contacts":11},"Málaga","29010",{"type":54,"coordinates":702},[703,704],-4.42034,36.72016,{"lat":704,"lon":703},{"facility":47,"status":11,"city":707,"state":11,"zip":708,"country":683,"countryCode":684,"cosmosGeoPoint":709,"geoPoint":713,"contacts":11},"Palma de Mallorca","07198",{"type":54,"coordinates":710},[711,712],2.65024,39.56939,{"lat":712,"lon":711},{"facility":47,"status":11,"city":715,"state":11,"zip":716,"country":683,"countryCode":684,"cosmosGeoPoint":717,"geoPoint":721,"contacts":11},"Sabadell","08208",{"type":54,"coordinates":718},[719,720],2.10942,41.54329,{"lat":720,"lon":719},{"facility":47,"status":11,"city":723,"state":11,"zip":724,"country":683,"countryCode":684,"cosmosGeoPoint":725,"geoPoint":729,"contacts":11},"Seville","41003",{"type":54,"coordinates":726},[727,728],-5.97317,37.38283,{"lat":728,"lon":727},{"facility":47,"status":11,"city":723,"state":11,"zip":731,"country":683,"countryCode":684,"cosmosGeoPoint":732,"geoPoint":734,"contacts":11},"41009",{"type":54,"coordinates":733},[727,728],{"lat":728,"lon":727},{"facility":47,"status":11,"city":736,"state":11,"zip":737,"country":683,"countryCode":684,"cosmosGeoPoint":738,"geoPoint":742,"contacts":11},"Valencia","46026",{"type":54,"coordinates":739},[740,741],-0.37966,39.47391,{"lat":741,"lon":740},{"facility":47,"status":11,"city":744,"state":11,"zip":745,"country":746,"countryCode":747,"cosmosGeoPoint":748,"geoPoint":752,"contacts":11},"Gothenburg","413 45","Sweden","SE",{"type":54,"coordinates":749},[750,751],11.96679,57.70716,{"lat":751,"lon":750},{"facility":47,"status":11,"city":754,"state":11,"zip":755,"country":746,"countryCode":747,"cosmosGeoPoint":756,"geoPoint":760,"contacts":11},"Karlstad","651 85",{"type":54,"coordinates":757},[758,759],13.50357,59.3793,{"lat":759,"lon":758},{"facility":47,"status":11,"city":762,"state":11,"zip":763,"country":746,"countryCode":747,"cosmosGeoPoint":764,"geoPoint":768,"contacts":11},"Lund","221 85",{"type":54,"coordinates":765},[766,767],13.19321,55.70584,{"lat":767,"lon":766},{"facility":47,"status":11,"city":770,"state":11,"zip":771,"country":746,"countryCode":747,"cosmosGeoPoint":772,"geoPoint":776,"contacts":11},"Stockholm","141 86",{"type":54,"coordinates":773},[774,775],18.06871,59.32938,{"lat":775,"lon":774},{"facility":47,"status":11,"city":778,"state":11,"zip":779,"country":780,"countryCode":781,"cosmosGeoPoint":782,"geoPoint":786,"contacts":11},"Kyiv","02091","Ukraine","UA",{"type":54,"coordinates":783},[784,785],30.5238,50.45466,{"lat":785,"lon":784},{"facility":47,"status":11,"city":778,"state":11,"zip":788,"country":780,"countryCode":781,"cosmosGeoPoint":789,"geoPoint":791,"contacts":11},"02232",{"type":54,"coordinates":790},[784,785],{"lat":785,"lon":784},{"facility":47,"status":11,"city":778,"state":11,"zip":793,"country":780,"countryCode":781,"cosmosGeoPoint":794,"geoPoint":796,"contacts":11},"03049",{"type":54,"coordinates":795},[784,785],{"lat":785,"lon":784},{"facility":47,"status":11,"city":778,"state":11,"zip":798,"country":780,"countryCode":781,"cosmosGeoPoint":799,"geoPoint":801,"contacts":11},"04053",{"type":54,"coordinates":800},[784,785],{"lat":785,"lon":784},{"facility":47,"status":11,"city":778,"state":11,"zip":803,"country":780,"countryCode":781,"cosmosGeoPoint":804,"geoPoint":806,"contacts":11},"04114",{"type":54,"coordinates":805},[784,785],{"lat":785,"lon":784},{"facility":47,"status":11,"city":808,"state":11,"zip":809,"country":780,"countryCode":781,"cosmosGeoPoint":810,"geoPoint":814,"contacts":11},"Vinnytsia","21010",{"type":54,"coordinates":811},[812,813],28.46871,49.2322,{"lat":813,"lon":812},{"facility":47,"status":11,"city":816,"state":11,"zip":817,"country":780,"countryCode":781,"cosmosGeoPoint":818,"geoPoint":822,"contacts":11},"Zhytomyr","10002",{"type":54,"coordinates":819},[820,821],28.67913,50.26235,{"lat":821,"lon":820},{"facility":47,"status":11,"city":824,"state":11,"zip":825,"country":826,"countryCode":827,"cosmosGeoPoint":828,"geoPoint":832,"contacts":11},"Belfast","BT12 6BA","United Kingdom","UK",{"type":54,"coordinates":829},[830,831],-5.92541,54.59682,{"lat":831,"lon":830},{"facility":47,"status":11,"city":834,"state":11,"zip":835,"country":826,"countryCode":827,"cosmosGeoPoint":836,"geoPoint":840,"contacts":11},"Blackburn","BB2 3HH",{"type":54,"coordinates":837},[838,839],-2.48333,53.75,{"lat":839,"lon":838},{"facility":47,"status":11,"city":842,"state":11,"zip":843,"country":826,"countryCode":827,"cosmosGeoPoint":844,"geoPoint":848,"contacts":11},"Bristol","BS10 5NB",{"type":54,"coordinates":845},[846,847],-2.59665,51.45523,{"lat":847,"lon":846},{"facility":47,"status":11,"city":850,"state":11,"zip":851,"country":826,"countryCode":827,"cosmosGeoPoint":852,"geoPoint":856,"contacts":11},"Cardiff","CF14 4XW",{"type":54,"coordinates":853},[854,855],-3.18,51.48,{"lat":855,"lon":854},{"facility":47,"status":11,"city":858,"state":11,"zip":859,"country":826,"countryCode":827,"cosmosGeoPoint":860,"geoPoint":864,"contacts":11},"Chester","CH2 1UL",{"type":54,"coordinates":861},[862,863],-2.89189,53.1905,{"lat":863,"lon":862},{"facility":47,"status":11,"city":866,"state":11,"zip":867,"country":826,"countryCode":827,"cosmosGeoPoint":11,"geoPoint":11,"contacts":11},"Edgbaston, Birmingham","B15 2TH",{"facility":47,"status":11,"city":869,"state":11,"zip":870,"country":826,"countryCode":827,"cosmosGeoPoint":871,"geoPoint":875,"contacts":11},"London","E1 2AT",{"type":54,"coordinates":872},[873,874],-0.12574,51.50853,{"lat":874,"lon":873},{"facility":47,"status":11,"city":869,"state":11,"zip":877,"country":826,"countryCode":827,"cosmosGeoPoint":878,"geoPoint":880,"contacts":11},"W2 1NY",{"type":54,"coordinates":879},[873,874],{"lat":874,"lon":873},{"facility":47,"status":11,"city":882,"state":11,"zip":883,"country":826,"countryCode":827,"cosmosGeoPoint":884,"geoPoint":888,"contacts":11},"Newcastle upon Tyne","NE1 4LP",{"type":54,"coordinates":885},[886,887],-1.61396,54.97328,{"lat":887,"lon":886},{"facility":47,"status":11,"city":890,"state":11,"zip":891,"country":826,"countryCode":827,"cosmosGeoPoint":892,"geoPoint":896,"contacts":11},"Plymouth","PL8 8DQ",{"type":54,"coordinates":893},[894,895],-4.14305,50.37153,{"lat":895,"lon":894},{"facility":47,"status":11,"city":898,"state":11,"zip":899,"country":826,"countryCode":827,"cosmosGeoPoint":900,"geoPoint":904,"contacts":11},"Sheffield","S5 7AU",{"type":54,"coordinates":901},[902,903],-1.4659,53.38297,{"lat":903,"lon":902},{"facility":47,"status":11,"city":906,"state":11,"zip":907,"country":826,"countryCode":827,"cosmosGeoPoint":908,"geoPoint":912,"contacts":11},"Stevenage","SG1 4AB",{"type":54,"coordinates":909},[910,911],-0.20256,51.90224,{"lat":911,"lon":910},{"facility":47,"status":11,"city":914,"state":11,"zip":915,"country":826,"countryCode":827,"cosmosGeoPoint":916,"geoPoint":920,"contacts":11},"Swansea","SA2 8PP",{"type":54,"coordinates":917},[918,919],-3.94323,51.62079,{"lat":919,"lon":918},{"type":922,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100243118","phase-2-a-clinical-proof-of-principle-trial-in-adult-subjects-with-newly-diagnosed-type-1-diabetes-mellitus-investigating-the-effect-of-nnc0114-0006-and-liraglutide-on-preservation-of-beta-cell-function-100243118",true,"NCT02443155","A Clinical Proof-of-principle Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of NNC0114-0006 and Liraglutide on Preservation of Beta-cell Function","A Randomised, Double-blind, Double-dummy, Placebo-controlled, Parallel-group Multi-centre Clinical Proof-of-principle Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of NNC0114-0006 and Liraglutide on Preservation of Beta-cell Function","Inclusion Criteria:\n\n* Informed consent obtained before any trial-related activities. Trial-related activities are any procedures that are carried out as part of the trial, including activities to determine suitability for the trial\n* T1DM (type 1 diabetes mellitus) (as diagnosed clinically) for not more than 20 weeks prior to screening - Male or female, aged 18-45 (both inclusive) at the time of signing the informed consent form\n* Non-fasting peak C-peptide higher or equal to 0.2 nmol\u002Fl at visit 2\n* BMI (body mass index) higher or equal to 18.5 kg\u002Fm\\^2\n* Presence of one or more islet specific auto antibodies (glutamic acid decarboxylase (GAD), islet antigen-2 (IA2) or zinc-transporter 8 (ZnT8)) at screening\n* Insulin dependence unless in temporary spontaneous remission (honeymoon period)\n\nExclusion Criteria:\n\n* Daily insulin usage above 1 U\u002Fkg per day at screening or use of continuous subcutaneous insulin infusion (CSII)\n* History of recurrent (e.g. several times a year) of severe (e.g. pneumonia) or chronic infections or conditions predisposing to chronic infections (e.g., bronchiectasis and chronic osteomyelitis)\n* History of severe systemic fungal infection within the past 12 months prior to screening unless treated and resolved with appropriate documented therapy\n* Vaccination within 4 weeks before randomisation, Visit 3 (V3)\n* Receipt of any other concomitant medications or herbal products that can influence the immune system within 90 days prior to screening (V1)\n* History of pancreatitis (acute or chronic)\n* Family or personal history of Multiple Endocrine Neoplasia Type 2 (MEN2) or Medullary Thyroid Carcinoma (MTC)\n* Any past or current diagnosis of malignant neoplasms\n* Known impairment of the immune system, except for T1DM, coeliac disease, alopecia, autoimmune antibodies not considered clinical important (e.g. thyroid antibodies without any clinically important thyroid disease), and vitiligo",false,"ALL","18 Years","45 Years",{"count":935,"type":936},308,"ACTUAL","INTERVENTIONAL",[939],"PHASE2","This trial is conducted globally. The aim of this trial is to assess the clinical proof-of-principle of NNC0114-0006 and liraglutide on preservation of beta-cell function in adult subjects with newly diagnosed type 1 diabetes mellitus.",[942,943],"Diabetes","Diabetes Mellitus, Type 1","COMPLETED","2021-03-10",{"date":947,"type":936},"2021-04-09",{"date":949,"type":936},"2015-11-10",{"date":951,"type":936},"2019-02-27",{"name":5,"class":6},108]