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Significant hepatic disease, including, but not limited to, chronic active hepatitis and\u002For severe hepatic insufficiency\n* Aspartate Aminotransferase (AST) or Alanine Aminotransferase (ALT) \\> 3X ULN\n* Total Bilirubin (TB) \\>2 mg\u002FdL (34.2 μmol\u002FL)\n* History of acute kidney injury requiring renal replacement therapy (dialysis or ultrafiltration) or any biopsy or imaging verifying intercurrent kidney disease other than diabetic nephropathy or diabetic nephropathy with nephrosclerosis\n* Ongoing treatment with a SGLT2 inhibitor, GLP-1 agonist or DPP4 inhibitors\n* Any condition which, in the judgment of the Investigator, may render the patient unable to complete the study or which may pose a significant risk to the patient or patient suspected or with confirmed poor protocol or medication compliance",false,"ALL","18 Years","130 Years",{"count":902,"type":903},459,"ACTUAL","INTERVENTIONAL",[906,907],"PHASE2","PHASE3","The purpose of this clinical research study is to 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