[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100181852":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":27,"locations":28,"responsibleParty":42,"collaborators":27,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":27,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":27,"maxAge":27,"enrollmentInfo":54,"targetDuration":27,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":67,"whyStopped":27,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"University of the Punjab","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"periodontal treatment group","EXPERIMENTAL","non surgical periodontal therapy will be given to study subjects which will be selected by randomization from total study sample. at the end of study, serum albumin levels of both study and control groups will be compared.",[13],"Procedure: non-surgical periodontal therapy",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","non-surgical periodontal therapy","dental scaling and root planing of full mouth will be done",[9],[21],"dental scaling and root planing",[23],{"name":24,"affiliation":25,"role":26},"Ayyaz A Khan, PhD","Shaikh Zayed Medical CompleX lahore","STUDY_DIRECTOR",null,[29],{"facility":30,"status":27,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":27},"Shaikh Zayed Medical Complex","Lahore","Punjab Province","54000","Pakistan","PK",{"type":37,"coordinates":38},"Point",[39,40],74.35071,31.558,{"lat":40,"lon":39},{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"PRINCIPAL_INVESTIGATOR","Dr Arsalan Wahid","Principal Investigator","100181852","phase-2-effect-of-non-surgical-periodontal-therapy-on-serum-albumin-levels-of-patients-on-maintenance-hemodialysis-therapy-100181852",false,"NCT01641757","Effect of Non-Surgical Periodontal Therapy on Serum Albumin Levels of Patients on Maintenance Hemodialysis Therapy,","Effect of Non-Surgical Periodontal Therapy on Serum Albumin Levels of Patients on Maintenance Hemodialysis Therapy, A Randomized Control Trial","Inclusion Criteria:\n\n1. Chronic Kidney Disease patients, who are receiving hemodialysis therapy for \\>3 months. of all ages and both gender and are able to give informed consent.\n2. Have at least 14 teeth (excluding third molars) in oral cavity shall be included in study.\n\nExclusion Criteria:\n\n1. Patients have had periodontal therapy \\\u003C1 year.\n2. Diabetes Mellitus\n3. Liver disease","ALL",{"count":55,"type":56},160,"ACTUAL","INTERVENTIONAL",[59],"PHASE2","Periodontitis is a destructive chronic infection of the gums, ligaments, and bone, predominantly caused by Gram-negative bacteria. Individuals with periodontal disease are at increased risk of systemic diseases. Increased prevalence of periodontal disease has been reported in patients with chronic kidney disease, especially in dialysis patients. Chronic kidney disease (CKD) is the progressive loss of kidney function over time. When kidneys loose their 85-90 % function, dialysis is performed. Efficacy of dialysis is checked by serum albumin levels. Lower-than-normal levels of serum albumin may be a sign of kidney diseases. Hypoalbuminemia has been demonstrated to be a strong predictor of death in chronic renal failure. A proposed mechanism for the effect of periodontitis on the development of kidney disease is systemic inflammation. The deleterious effects of systemic inflammation on kidney function could occur during the period of active periodontal infection and accumulate during the life time of the individual. This randomized control trial is designed to observe the effect of non-surgical periodontal therapy on serum albumin levels of patients on maintenance hemodialysis therapy. Patients will undergo periodontal examination and their serum albumin levels will be checked. Then they will be randomly divided in two groups. One group will be given non surgical periodontal treatment and second group will be offered late treatment. After 6 weeks 1st group will be reevaluated by serum albumin level and periodontal examination to observe the effect of non-surgical periodontal therapy. Statistical analyses shall be performed using SPSS software. T tests and Chi-sq tests shall be used to test differences according to periodontal status for continuous and categorical variables, respectively. The level of significance is set at p\\\u003C0.05.",[62,63],"End Stage Renal Failure on Dialysis","Periodontitis",[65,66],"hemodialysis","periodontitis","UNKNOWN","2012-07-17",{"date":70,"type":71},"2012-07-18","ESTIMATED",{"date":73,"type":27},"2012-05",{"date":75,"type":71},"2012-10",{"name":5,"class":6},1]