[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100340051":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":24,"locations":24,"responsibleParty":25,"collaborators":24,"id":29,"slug":30,"hasResults":31,"nctId":32,"briefTitle":33,"officialTitle":34,"acronym":24,"eligibilityCriteria":35,"healthyVolunteers":31,"sex":36,"minAge":24,"maxAge":24,"enrollmentInfo":37,"targetDuration":24,"studyType":40,"phases":41,"briefSummary":43,"conditions":44,"keywords":24,"overallStatus":46,"whyStopped":24,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":24},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention","EXPERIMENTAL","250 μM of vitamin C will be used with the platelet rich fibrin",[13],"Combination Product: combination of vitamin C and platelet rich fibrin",{"label":15,"type":16,"description":17,"interventionNames":18},"Comparator","ACTIVE_COMPARATOR","using platelet rich fibrin alone",[13],[20],{"type":21,"name":22,"description":22,"armGroupLabels":23,"otherNames":24},"COMBINATION_PRODUCT","combination of vitamin C and platelet rich fibrin",[15,9],null,{"type":26,"investigatorFullName":27,"investigatorTitle":28,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Mohamed Talaat Mohamed Mahmoud El Behwashy","Dentist","100340051","phase-2-evaluation-of-the-effect-of-incorporation-of-vitamin-c-into-platelet-rich-fibrin-scaffold-in-treatment-of-intra-osseous-periodontal-defects-100340051",false,"NCT03707483","Evaluation of the Effect of Incorporation of Vitamin C Into Platelet Rich Fibrin Scaffold in Treatment of Intra-osseous Periodontal Defects","The Effect of Combination of Vitamin C and Platelet Rich Fibrin (PRF) Versus Platelet Rich Fibrin Alone on Clinical Attachment Gain in Patients With Stage III Periodontitis: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patient consulting in the outpatient clinic.\n* Able to tolerate surgical periodontal procedures.\n* Patient ready to perform oral hygiene instructions.\n* Compliance with the maintenance program.\n* Provide informed consent.\n* Accept the 6 months follow-up period\n* Mature permanent tooth.\n* Tooth with two or three-walled intra-bony defect, CAL ≥ 5mm with intra-osseous defect ≥ 3mm.\n\nExclusion Criteria:\n\n* Medically compromised patients.\n* Pregnant or nursing women.\n* Uncooperative patients.\n* Smokers.\n* Teeth with one wall intra-bony defect.\n* Teeth with supra-bony defects.\n* Teeth with grade III mobility.","ALL",{"count":38,"type":39},20,"ESTIMATED","INTERVENTIONAL",[42],"PHASE2","This study is meant to assess clinically the possible predictable clinical attachment gain regarding the use of vitamin C with platelet rich fibrin versus platelet rich fibrin alone in the treatment of periodontal intrabony defects",[45],"Periodontal Bone Loss","UNKNOWN","2019-02-06",{"date":49,"type":50},"2019-02-07","ACTUAL",{"date":52,"type":39},"2019-02",{"date":54,"type":39},"2020-03",{"name":5,"class":6}]