[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100108664":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":21,"centralContacts":7,"locations":26,"responsibleParty":39,"collaborators":7,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":7,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":66,"whyStopped":7,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Technische Universität Dresden","OTHER",null,[9,15],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":13},"DRUG","Ketokonazol 2% cream","twice a day at 2 times,2 out of 5 areas have to be treated for 4 weeks\u002F7 days a week",[14],"Nizoral cream",{"type":16,"name":17,"description":18,"armGroupLabels":7,"otherNames":19},"RADIATION","UVB-radiation 311nm","3 out of 5 areas are radiated for 4 weeks every MO\u002FDI\u002FDO\u002FFR starting MED orientated, intensified everytime 0,03 J\u002Fqcm",[20],"UVB Radiation, phototherapy, narrow-band ultraviolet B phototherapy",[22],{"name":23,"affiliation":24,"role":25},"Gottfried Wozel, Prof. Dr.med","Department of Dermatology, Medical Faculty, Technical University Dresden, Germany","PRINCIPAL_INVESTIGATOR",[27],{"facility":28,"status":7,"city":29,"state":7,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":7},"Department of Dermatology, Medical Faculty, TU Dresden","Dresden","01307","Germany","DE",{"type":34,"coordinates":35},"Point",[36,37],13.73832,51.05089,{"lat":37,"lon":36},{"type":7,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":40,"oldOrganization":41},"Prof. Dr. med. Gottfried Wozel","Technical University Dresden, Department of Dermatology","100108664","phase-2-investigation-of-antipsoriatic-effects-of-uvb-induced-synthesis-of-1alpha-25-dihydroxyvitamin-d3-1alpha-25oh2d3-calcitriolin-keratinocytes-of-psoriatic-skin-using-cytochrom-pcypinhibitor-ketokonazol-100108664",false,"NCT00678756","Investigation of Antipsoriatic Effects of UVB-induced Synthesis of 1alpha, 25-Dihydroxyvitamin D3 (1alpha, 25(OH)2D3, Calcitriol)in Keratinocytes of Psoriatic Skin, Using Cytochrom-P(CYP)Inhibitor Ketokonazol","VITAKET","Inclusion Criteria:\n\n* age: 18- 80\n* diagnosis of psoriasis vulgaris (mild- middle)\n* no other current antipsoriatic therapy (systemic\u002Ftopical)\n* at least 5 psoriatic areas of 5x5 cm\n\nExclusion Criteria:\n\n* pregnancy\u002Fnursing mothers\n* women in reproductive age without adequate contraception\n* severe and acute forms of psoriasis vulgaris\n* patients receiving systemic or topical antipsoroatic treatment in past 3 month\n* UV-therapy in past 3 month\n* patients having a positive anamnesis for squamous cell carcinoma, malignant melanoma, basalioma\n* epilepsy","ALL","18 Years","80 Years",{"count":53,"type":54},12,"ESTIMATED","INTERVENTIONAL",[57],"PHASE2","Exploration of antipsoriatic effects of UVB-therapy +\u002F- CYP-inhibitor Ketokonazol on affected psoriatic skin",[60],"Psoriasis Vulgaris",[62,63,64,65],"Psoriasis vulgaris,","vitamin D, UVB-phototherapy, ketokonazol,","Optical Coherence Tomography,","local PASI, Nizoral","UNKNOWN","2010-06-07",{"date":69,"type":54},"2010-06-08",{"date":71,"type":7},"2008-03",{"date":73,"type":54},"2009-12",{"name":5,"class":6},1]