[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100117469":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":26,"locations":34,"responsibleParty":47,"collaborators":26,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":26,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":26,"enrollmentInfo":59,"targetDuration":26,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":72,"whyStopped":73,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Stamford Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Capsaicin patch","ACTIVE_COMPARATOR","Patches will contain capsaicin 0.1% (500 mcg)",[13],"Drug: Capsaicin",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo patch","PLACEBO_COMPARATOR","Placebo hydrogel patches will be 2.5 cm in diameter with a breathable cloth backing.",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Capsaicin","Each group will undergo two 4-week treatment arms separated by a 4-week wash-out period. Participants will apply 1 hydrogel patch on both the right-sided and left-sided neck and shoulder girdle on the skin overlying a myofascial trigger point. No more than 2 patches will be used on each subject per treatment. During each 24-hour period, the patches will be placed on the skin for 12 hours and will be removed for 12 hours. Placebo hydrogel patches will be 2.5 cm in diameter with a breathable cloth backing. The experimental patches will be identical to placebo patches except will contain capsaicin 0.1% (500 mcg).",[9],null,{"type":22,"name":28,"description":24,"armGroupLabels":29,"otherNames":26},"Placebo",[15],[31],{"name":32,"affiliation":5,"role":33},"Marc Brodsky, MD","PRINCIPAL_INVESTIGATOR",[35],{"facility":5,"status":26,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":26},"Stamford","Connecticut","06902","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-73.53873,41.05343,{"lat":45,"lon":44},{"type":26,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":48,"oldOrganization":49},"Marc Brodsky, Medical Director","Center for Integrative Medicine and Wellness at Stamford Hospital","100117469","phase-2-trial-to-evaluate-the-efficacy-of-topical-capsaicin-to-reduce-pain-and-improve-health-related-quality-of-life-in-adults-with-chronic-myofascial-neck-pain-100117469",false,"NCT00795106","Trial to Evaluate the Efficacy of Topical Capsaicin to Reduce Pain and Improve Health-related Quality of Life in Adults With Chronic Myofascial Neck Pain","Double-blinded, Cross-over Randomized Controlled Trial to Evaluate the Efficacy of Topical Capsaicin to Reduce Pain and Improve Health-related Quality of Life in Adults With Chronic Myofascial Neck Pain","Inclusion Criteria:\n\n* Adults over 18 years of age\n* Speak, read, and write English who have greater than 3 month duration of myofascial neck pain.\n\nExclusion Criteria:\n\n* Patients who have used capsaicin in the last 4 months and patients with allergy to capsaicin\n* Rash\u002Finfection overlying neck and shoulder girdle area\n* Radiculopathy or structural abnormalities in the area being treated\n* Unstable underlying diseases such as cardiovascular, hepatic, renal and CNS disorders will be excluded from the study\n* Pregnant or breast-feeding women will not be allowed to participate in the study, and women of child bearing age will be using an effective method of birth control.","ALL","18 Years",{"count":60,"type":61},0,"ACTUAL","INTERVENTIONAL",[64],"PHASE2","Chronic neck pain is a common condition that can negatively impact quality of life. Substance P is one of the chemicals in the body that can transmit pain signals from overloaded neck muscles to the brain. Topical capsaicin blocks the action of Substance P by releasing, and subsequently depleting the body's store of Substance P in the nerves. Topical capsaicin has been reported to be an effective therapy for a number of persistent pain conditions including diabetic neuropathy, post-herpetic neuralgia, osteoarthritis, rheumatoid arthritis, and post-mastectomy pain. This study will evaluate the efficacy of topical capsaicin to reduce pain and improve health-related quality of life in adults with chronic muscular neck pain.",[67],"Myofascial Pain Syndrome",[23,69,70,71],"hydrogel","myofascial pain syndrome","neck pain","WITHDRAWN","Difficulty finding a monitor","2016-12-05",{"date":76,"type":77},"2016-12-06","ESTIMATED",{"date":79,"type":26},"2009-11",{"date":81,"type":61},"2010-11",{"name":5,"class":6},1]