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Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas","ICONIC-TOTAL","Inclusion Criteria:\n\n* Diagnosis of plaque psoriasis, with or without psoriatic arthritis (PsA), for at least 26 weeks prior to the first administration of study intervention\n* Candidate for phototherapy or systemic treatment for plaque psoriasis\n* Need to meet criteria: Total body surface area (BSA) greater than or equal to (\\>=)1 percent (%) at screening and baseline, and investigator global assessment (IGA) (overall) \\>=2 at screening and baseline and at least one of the following: scalp-specific investigator global assessment (ss-IGA) score \\>=3 at screening and baseline, and\u002For static physician's global assessment of genitalia (sPGA-G) \\>=3 at screening and baseline, and\u002For physician's global assessment of hands and feet (hf-PGA) score \\>=3 at screening and baseline\n* Failed to respond to at least 1 topical therapy (example, corticosteroids, calcineurin inhibitors, and\u002For vitamin D analogs) used for treatment of psoriasis\n* Confirmation of plaque psoriasis in a non-special area (example, areas excluding scalp, genital, palmoplantar) at screening and baseline\n\nExclusion Criteria:\n\n* Nonplaque form of psoriasis (example, erythrodermic, guttate, or pustular)\n* Dermatoses other than plaque psoriasis (such as contact dermatitis) or palmoplantar pustulosis of the palmoplantar area (if hf-PGA \\>=3 at baseline)\n* Current drug-induced psoriasis (example, a new onset of psoriasis or an exacerbation of psoriasis from beta blockers, calcium channel blockers, or lithium)\n* A current diagnosis or signs or symptoms of severe, progressive, or uncontrolled renal, liver, cardiac, vascular, pulmonary, gastrointestinal, endocrine, neurologic, hematologic, rheumatologic, psychiatric, or metabolic disturbances\n* Known allergies, hypersensitivity, or intolerance to JNJ-77242113 or its excipients",false,"ALL","12 Years",{"count":850,"type":851},311,"ACTUAL","INTERVENTIONAL",[854],"PHASE3","The purpose of the study is to see how effective JNJ-77242113 is in participants with plaque psoriasis affecting special areas (scalp, genital, and\u002For palms of the hands and the soles of the feet).",[857],"Plaque Psoriasis","ACTIVE_NOT_RECRUITING","2026-07-02",{"date":861,"type":851},"2026-07-06",{"date":863,"type":851},"2023-10-12",{"date":865,"type":866},"2027-02-17","ESTIMATED",{"name":5,"class":6},90]