[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100110863":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":23,"locations":33,"responsibleParty":46,"collaborators":23,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":23,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":23,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":71,"whyStopped":23,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"A. Vogel AG","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"2","ACTIVE_COMPARATOR","Drug: Echinacea\u002Fsage\n\npatients received additionally a placebo-spray for the synthetical comparator (chlorhexidine\u002Flidocaine) as the study was double dummy blinded.\n\nPatients had to apply spray every 2 hours with two puffs to the pharyngeal area up to a maximum of 10 times daily. Treatment duration was until illness was resolved or for a maximum of 5 consecutive days.\n\nArms: 1",[13],"Drug: echinacea\u002Fsage",{"label":15,"type":10,"description":16,"interventionNames":17},"1","Drug: Chlorhexidine\u002Flidocaine\n\npatients received additionally a placebo-spray for the synthetical comparator (echinacea\u002Fsage) as the study was double dummy blinded.\n\nPatients had to apply spray every 2 hours with two puffs to the pharyngeal area up to a maximum of 10 times daily. Treatment duration was until illness was resolved or for a maximum of 5 consecutive days.",[18],"Drug: chlorhexidine\u002Flidocaine",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":23},"DRUG","chlorhexidine\u002Flidocaine",null,[15],{"type":21,"name":26,"description":23,"armGroupLabels":27,"otherNames":23},"echinacea\u002Fsage",[9],[29],{"name":30,"affiliation":31,"role":32},"Dominique Kähler, MD","General practice, Hubstrasse 37, 9500 Wil, Switzerland","PRINCIPAL_INVESTIGATOR",[34],{"facility":35,"status":23,"city":36,"state":23,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":23},"Allergy Clinic","Landquart","7302","Switzerland","CH",{"type":41,"coordinates":42},"Point",[43,44],9.56667,46.95,{"lat":44,"lon":43},{"type":23,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":47,"oldOrganization":48},"Andy Suter, Head of Medical Dept.","Bioforce AG, Roggwil, Switzerland","100110863","phase-3-clinical-trial-for-assessment-of-safety-and-efficacy-of-a-echinaceasage-spray-compared-to-a-chlorhexidinelidocaine-spray-in-the-treatment-of-acute-sore-throats-100110863",false,"NCT00707902","Clinical Trial for Assessment of Safety and Efficacy of a Echinacea\u002FSage Spray Compared to a Chlorhexidine\u002FLidocaine Spray in the Treatment of Acute Sore Throats","Multicentric Randomized Double Blind Double Dummy Placebo Controlled Clinical Trial for Assessment of Safety and Efficacy of a Echinacea\u002FSage Spray in Comparison to a Chlorhexidine\u002FLidocaine Spray in the Treatment of Acute Sore Throats","Inclusion Criteria:\n\n* Age \\> 12 years;\n* Acute pharyngitis or tonsillitis with symptoms of throat pain and inflammation of the pharynx and\u002For tonsils;\n* Onset of sore throat less than 72 hours before inclusion ;\n* A Tonsillopharyngitis Severity Score ≥6;\n* Written informed consent.\n\nExclusion Criteria:\n\n* Analgesics \\\u003C12 hours;\n* Antibiotics \\\u003C24 hours; t\n* Topical throat pain medication \\\u003C4 hours;\n* Systemic corticosteroids within the last month;\n* Symptoms of primary bacterial pharyngitis or secondary bacterial infection;\n* Serious illness such as tumors; allergy to one of the ingredients; pregnancy or lactation;\n* Hypersensitivity to ibuprofen;\n* Participation in another clinical trial in the previous 30 days.","ALL","12 Years","75 Years",{"count":60,"type":61},154,"ACTUAL","INTERVENTIONAL",[64],"PHASE3","The aim of the study is to show non-inferiority of an echinacea\u002Fsage spray compared to a chlorhexidine\u002Flidocaine-spray in the treatment of acute sore throat during five days of treatment.\n\nMain outcome parameter is the non-inferiority in number of responders between the two treatment groups. A responder is defined as a reduction by 50% of the total baseline score taken prior to treatment start. The symptoms are assessed with a symptom score.",[67],"Pharyngitis",[69,67,70],"Sore throats,","Acute","COMPLETED","2008-06-30",{"date":74,"type":75},"2008-07-01","ESTIMATED",{"date":77,"type":23},"2006-02",{"date":79,"type":23},"2006-08",{"name":5,"class":6},1]