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Walla","99362",{"type":97,"coordinates":3404},[3405,3406],-118.34302,46.06458,{"lat":3406,"lon":3405},{"facility":3409,"status":56,"city":2734,"state":3410,"zip":3411,"country":94,"countryCode":95,"cosmosGeoPoint":3412,"geoPoint":3416,"contacts":56},"Forest Investigative Site 1377","West Virginia","25304",{"type":97,"coordinates":3413},[3414,3415],-81.63262,38.34982,{"lat":3415,"lon":3414},{"facility":3418,"status":56,"city":3419,"state":3420,"zip":3421,"country":94,"countryCode":95,"cosmosGeoPoint":3422,"geoPoint":3426,"contacts":56},"Forest Investigative Site 1367","Milwaukee","Wisconsin","53215",{"type":97,"coordinates":3423},[3424,3425],-87.90647,43.0389,{"lat":3425,"lon":3424},{"type":3428,"investigatorFullName":56,"investigatorTitle":56,"investigatorAffiliation":56,"oldNameTitle":56,"oldOrganization":56},"SPONSOR","100171644","phase-3-study-of-the-efficacy-and-safety-of-the-combination-of-two-fda-approved-oral-medications-nebivolol-and-valsartan-for-treatment-of-stage-1-or-2-hypertension-100171644",false,"NCT01508026","Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension","A Multicenter, Randomized, Double-blind, Placebo-Controlled, 8-Week Study to Evaluate the Safety and Efficacy of Nebivolol and Valsartan Given as a Fixed Dose Combination in Patients With Stage 1 or 2 Essential Hypertension","Inclusion Criteria:\n\n* Male or female outpatients of age 18 years or above\n* Patients diagnosed with stage 1 or stage 2 essential hypertension\n* Normal physical examination findings, electrocardiogram (ECG) results and chest x-ray; or abnormal findings judged by the Investigator to be not clinically significant\n\nExclusion Criteria:\n\n* Secondary hypertension or severe hypertension\n* Clinically significant cardiovascular disease or heart failure\n* Clinical significant respiratory disease that would prohibit the use of a beta blocker\n* A medical contraindication to discontinuing a current antihypertensive therapy\n* History of Type 1 diabetes mellitus\n* History of Severe Mental Illness except mild depression","ALL","18 Years",{"count":3439,"type":3440},4161,"ACTUAL","INTERVENTIONAL",[3443],"PHASE3","To evaluate the efficacy and safety of fixed-dose combination of nebivolol and valsartan compared to monotherapy and placebo in patients with stage 1 and stage 2 hypertension.",[3446,3447],"Stage 1 Hypertension","Stage 2 Hypertension",[3449,3450,3451],"Stage 1","Stage 2","Hypertension","COMPLETED","2014-03-28",{"date":3455,"type":3456},"2014-04-25","ESTIMATED",{"date":3458,"type":56},"2012-01",{"date":3460,"type":3440},"2013-05",{"name":5,"class":6},413]