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medicine","Odesa","65009",{"type":43,"coordinates":1514},[1515,1516],30.74383,46.48572,{"lat":1516,"lon":1515},{"facility":1519,"status":11,"city":1520,"state":11,"zip":11,"country":1467,"countryCode":1468,"cosmosGeoPoint":1521,"geoPoint":1525,"contacts":11},"Poltava Regional Clinical Hospital, Department of Urology","Poltava",{"type":43,"coordinates":1522},[1523,1524],34.55367,49.58925,{"lat":1524,"lon":1523},{"facility":1527,"status":11,"city":1528,"state":11,"zip":1529,"country":1467,"countryCode":1468,"cosmosGeoPoint":1530,"geoPoint":1534,"contacts":11},"Municipal Institution of Ternopil Regional Council, Ternopil University Hospital","Ternopil","46002",{"type":43,"coordinates":1531},[1532,1533],25.59067,49.55404,{"lat":1533,"lon":1532},{"type":1536,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100155950","phase-4-a-clinical-study-in-patients-with-overactive-bladder-with-leakage-of-urine-to-find-out-if-the-medicine-fesoterodine-works-in-those-patients-who-did-not-have-enough-response-to-the-medicine-tolterodine-100155950",true,"NCT01302054","A Clinical Study in Patients With Overactive Bladder With Leakage of Urine, to Find Out if the Medicine, Fesoterodine, Works in Those Patients Who Did Not Have Enough Response to the Medicine, Tolterodine.","A 14 Week Randomized Parallel Group Placebo-Controlled Double-Blind Multicentre Study Of Fesoterodine 8 Mg In Overactive Bladder Patients With Sub-Optimal Response To Tolterodine 4 Mg Extended Release (ER).","Inclusion Criteria:\n\n* Diagnosis of overactive bladder with symptoms for at least 6 months.\n* Moderate to severe incontinence episode frequency and subsequent sub-optimal response to tolterodine\n* Women of child-bearing potential must not intend to become pregnant, be pregnant or producing breast milk at the time of study entry, and must use contraception\n\nExclusion Criteria:\n\n* Conditions or prior treatment that may also affect bladder function\n* Clinically significant urinary tract infection (UTI)\n* Ongoing treatment with overactive bladder medications (these can be stopped at the first visit to allow entry into the study).",false,"ALL","18 Years",{"count":1548,"type":1549},990,"ACTUAL","INTERVENTIONAL",[1552],"PHASE4","Patients with overactive bladder are often treated with tolterodine, a medication that helps relax the bladder, helping symptoms of urinary incontinence and urinary frequency. Sometimes patients do not have a satisfactory response, and may benefit from trying an alternative oral medicine. Fesoterodine is related to tolterodine by producing the same active substance that acts on the bladder, but potentially at higher and more effective levels. So, a patient who has a poor response to tolterodine may still obtain a good response to fesoterodine. This study will help find out if this is what happens.",[1555],"Urinary Bladder, Overactive",[1557,1558,1559],"Bladder Overactive","Overactive urinary bladder","Overactive Bladder","COMPLETED","2018-11-07",{"date":1563,"type":1549},"2018-12-04",{"date":1565,"type":11},"2011-05",{"date":1567,"type":1549},"2012-05",{"name":5,"class":6},176]