[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100151512":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":11,"locations":31,"responsibleParty":394,"collaborators":11,"id":396,"slug":397,"hasResults":398,"nctId":399,"briefTitle":400,"officialTitle":401,"acronym":11,"eligibilityCriteria":402,"healthyVolunteers":403,"sex":404,"minAge":405,"maxAge":11,"enrollmentInfo":406,"targetDuration":11,"studyType":409,"phases":410,"briefSummary":412,"conditions":413,"keywords":11,"overallStatus":415,"whyStopped":11,"lastUpdateSubmitDate":416,"lastUpdatePostDateStruct":417,"startDateStruct":420,"completionDateStruct":422,"leadSponsor":424,"locationsCount":425},{"fullName":5,"class":6},"Pfizer","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Varenicline","EXPERIMENTAL",null,[13],"Drug: Varenicline",{"label":15,"type":16,"description":11,"interventionNames":17},"Placebo","PLACEBO_COMPARATOR",[18],"Drug: Placebo",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"DRUG","Varenicline 1mg twice daily",[9],{"type":21,"name":15,"description":25,"armGroupLabels":26,"otherNames":11},"Matched placebo twice daily",[15],[28],{"name":29,"affiliation":5,"role":30},"Pfizer CT.gov Call Center","STUDY_DIRECTOR",[32,45,51,61,71,81,91,101,111,123,133,142,152,163,172,181,190,202,212,222,232,242,251,260,269,280,289,298,309,318,327,336,345,357,367,376,385],{"facility":33,"status":11,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":11},"Ronald Reagan University of California Los Angeles Medical Center","Los Angeles","California","90095-6984","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-118.24368,34.05223,{"lat":43,"lon":42},{"facility":46,"status":11,"city":34,"state":35,"zip":47,"country":37,"countryCode":38,"cosmosGeoPoint":48,"geoPoint":50,"contacts":11},"University of California Los Angeles David Geffen School of Medicine","90095",{"type":40,"coordinates":49},[42,43],{"lat":43,"lon":42},{"facility":52,"status":11,"city":53,"state":54,"zip":55,"country":37,"countryCode":38,"cosmosGeoPoint":56,"geoPoint":60,"contacts":11},"Avail Clinical Research, LLC","DeLand","Florida","32720",{"type":40,"coordinates":57},[58,59],-81.30312,29.02832,{"lat":59,"lon":58},{"facility":62,"status":11,"city":63,"state":64,"zip":65,"country":37,"countryCode":38,"cosmosGeoPoint":66,"geoPoint":70,"contacts":11},"Central Kentucky Research Associates, Inc.","Lexington","Kentucky","40509",{"type":40,"coordinates":67},[68,69],-84.47772,37.98869,{"lat":69,"lon":68},{"facility":72,"status":11,"city":73,"state":74,"zip":75,"country":37,"countryCode":38,"cosmosGeoPoint":76,"geoPoint":80,"contacts":11},"The University of Maryland","College Park","Maryland","20742",{"type":40,"coordinates":77},[78,79],-76.93692,38.98067,{"lat":79,"lon":78},{"facility":82,"status":11,"city":83,"state":84,"zip":85,"country":37,"countryCode":38,"cosmosGeoPoint":86,"geoPoint":90,"contacts":11},"The Center for Pharmaceutical Research, PC","Kansas City","Missouri","64114",{"type":40,"coordinates":87},[88,89],-94.57857,39.09973,{"lat":89,"lon":88},{"facility":92,"status":11,"city":93,"state":94,"zip":95,"country":37,"countryCode":38,"cosmosGeoPoint":96,"geoPoint":100,"contacts":11},"Oregon Health and Science University","Portland","Oregon","97239-3098",{"type":40,"coordinates":97},[98,99],-122.67621,45.52345,{"lat":99,"lon":98},{"facility":102,"status":11,"city":103,"state":104,"zip":105,"country":37,"countryCode":38,"cosmosGeoPoint":106,"geoPoint":110,"contacts":11},"Clinical Research Associates, Inc.","Nashville","Tennessee","37203",{"type":40,"coordinates":107},[108,109],-86.78444,36.16589,{"lat":109,"lon":108},{"facility":112,"status":11,"city":113,"state":114,"zip":115,"country":116,"countryCode":117,"cosmosGeoPoint":118,"geoPoint":122,"contacts":11},"Australian Clinical Research Network","Maroubra","New South Wales","2035","Australia","AU",{"type":40,"coordinates":119},[120,121],151.23333,-33.95,{"lat":121,"lon":120},{"facility":124,"status":11,"city":125,"state":126,"zip":127,"country":116,"countryCode":117,"cosmosGeoPoint":128,"geoPoint":132,"contacts":11},"Royal Brisbane and Women's Hospital","Herston","Queensland","4029",{"type":40,"coordinates":129},[130,131],153.01852,-27.44453,{"lat":131,"lon":130},{"facility":134,"status":11,"city":135,"state":126,"zip":136,"country":116,"countryCode":117,"cosmosGeoPoint":137,"geoPoint":141,"contacts":11},"AusTrials Australia","Sherwood","4075",{"type":40,"coordinates":138},[139,140],152.98216,-27.53034,{"lat":140,"lon":139},{"facility":143,"status":11,"city":144,"state":145,"zip":146,"country":116,"countryCode":117,"cosmosGeoPoint":147,"geoPoint":151,"contacts":11},"Emeritus Research","Malvern","Victoria","3145",{"type":40,"coordinates":148},[149,150],145.02811,-37.86259,{"lat":150,"lon":149},{"facility":153,"status":11,"city":154,"state":11,"zip":155,"country":156,"countryCode":157,"cosmosGeoPoint":158,"geoPoint":162,"contacts":11},"Universitair Ziekenhuis Antwerpen, Afdeling Pneumologie","Edegem","2650","Belgium","BE",{"type":40,"coordinates":159},[160,161],4.44504,51.15662,{"lat":161,"lon":160},{"facility":164,"status":11,"city":165,"state":11,"zip":166,"country":156,"countryCode":157,"cosmosGeoPoint":167,"geoPoint":171,"contacts":11},"Universitaire Ziekenhuizen Leuven\u002FPneumologie","Leuven","3000",{"type":40,"coordinates":168},[169,170],4.70093,50.87959,{"lat":170,"lon":169},{"facility":173,"status":11,"city":174,"state":11,"zip":175,"country":156,"countryCode":157,"cosmosGeoPoint":176,"geoPoint":180,"contacts":11},"Centre Hospitalier Universitaire de Liege","Liège","4000",{"type":40,"coordinates":177},[178,179],5.56749,50.63373,{"lat":179,"lon":178},{"facility":182,"status":11,"city":183,"state":11,"zip":184,"country":156,"countryCode":157,"cosmosGeoPoint":185,"geoPoint":189,"contacts":11},"Cliniques Universitaires U.C.L. de Mont-Godinne\u002FLaboratoire","Yvoir","5530",{"type":40,"coordinates":186},[187,188],4.88059,50.3279,{"lat":188,"lon":187},{"facility":191,"status":11,"city":192,"state":193,"zip":194,"country":195,"countryCode":196,"cosmosGeoPoint":197,"geoPoint":201,"contacts":11},"Office of Dr. Ronald Collette","Burnaby","British Columbia","V5G 1T4","Canada","CA",{"type":40,"coordinates":198},[199,200],-122.95263,49.26636,{"lat":200,"lon":199},{"facility":203,"status":11,"city":204,"state":205,"zip":206,"country":195,"countryCode":196,"cosmosGeoPoint":207,"geoPoint":211,"contacts":11},"White Hills Medical Clinic","St. John's","Newfoundland and Labrador","A1A 3R5",{"type":40,"coordinates":208},[209,210],-52.70931,47.56494,{"lat":210,"lon":209},{"facility":213,"status":11,"city":214,"state":215,"zip":216,"country":195,"countryCode":196,"cosmosGeoPoint":217,"geoPoint":221,"contacts":11},"Canadian Phase Onward Inc.","Toronto","Ontario","M3H 5S4",{"type":40,"coordinates":218},[219,220],-79.39864,43.70643,{"lat":220,"lon":219},{"facility":223,"status":11,"city":224,"state":225,"zip":226,"country":195,"countryCode":196,"cosmosGeoPoint":227,"geoPoint":231,"contacts":11},"Clinique des maladies Lipidiques de Quebec","Québec","Quebec","G1V 4M6",{"type":40,"coordinates":228},[229,230],-71.21454,46.81228,{"lat":230,"lon":229},{"facility":233,"status":11,"city":234,"state":11,"zip":235,"country":236,"countryCode":11,"cosmosGeoPoint":237,"geoPoint":241,"contacts":11},"Fakultni nemocnice Brno","Brno","625 00","Czechia",{"type":40,"coordinates":238},[239,240],16.60796,49.19522,{"lat":240,"lon":239},{"facility":243,"status":11,"city":244,"state":11,"zip":245,"country":236,"countryCode":11,"cosmosGeoPoint":246,"geoPoint":250,"contacts":11},"Krajska nemocnice Liberec a.s., Plicni oddeleni","Liberec","460 01",{"type":40,"coordinates":247},[248,249],15.05619,50.76711,{"lat":249,"lon":248},{"facility":252,"status":11,"city":253,"state":11,"zip":254,"country":236,"countryCode":11,"cosmosGeoPoint":255,"geoPoint":259,"contacts":11},"Mestska nemocnice Ostrava, Plicni oddeleni","Ostrava","728 80",{"type":40,"coordinates":256},[257,258],18.28204,49.83465,{"lat":258,"lon":257},{"facility":261,"status":11,"city":262,"state":11,"zip":263,"country":236,"countryCode":11,"cosmosGeoPoint":264,"geoPoint":268,"contacts":11},"Vseobecna fakultni nemocnice v Praze","Prague","120 00",{"type":40,"coordinates":265},[266,267],14.42076,50.08804,{"lat":267,"lon":266},{"facility":270,"status":11,"city":271,"state":11,"zip":272,"country":273,"countryCode":274,"cosmosGeoPoint":275,"geoPoint":279,"contacts":11},"CHU de la Cavale Blanche","Brest","29609","France","FR",{"type":40,"coordinates":276},[277,278],-4.48628,48.39029,{"lat":278,"lon":277},{"facility":281,"status":11,"city":282,"state":11,"zip":283,"country":273,"countryCode":274,"cosmosGeoPoint":284,"geoPoint":288,"contacts":11},"CHU Côte de Nacre, Unité de Coordination de Tabacologie","Caen","14033",{"type":40,"coordinates":285},[286,287],-0.35912,49.18585,{"lat":287,"lon":286},{"facility":290,"status":11,"city":291,"state":11,"zip":292,"country":273,"countryCode":274,"cosmosGeoPoint":293,"geoPoint":297,"contacts":11},"Hopital Arnaud de Villeneuve","Montpellier","34295",{"type":40,"coordinates":294},[295,296],3.87635,43.61093,{"lat":296,"lon":295},{"facility":299,"status":11,"city":300,"state":301,"zip":302,"country":301,"countryCode":303,"cosmosGeoPoint":304,"geoPoint":308,"contacts":11},"Universitaetsklinikum Goettingen Zentrum Innere Medizin Abteilung Kardiologie und Pneumologie","Göttingen","Germany","37075","DE",{"type":40,"coordinates":305},[306,307],9.93228,51.53443,{"lat":307,"lon":306},{"facility":310,"status":11,"city":311,"state":11,"zip":312,"country":301,"countryCode":303,"cosmosGeoPoint":313,"geoPoint":317,"contacts":11},"Klinische Forschung Berlin","Berlin","10787",{"type":40,"coordinates":314},[315,316],13.41053,52.52437,{"lat":316,"lon":315},{"facility":319,"status":11,"city":320,"state":11,"zip":321,"country":301,"countryCode":303,"cosmosGeoPoint":322,"geoPoint":326,"contacts":11},"Klinische Forschung Hamburg GmbH","Hamburg","20253",{"type":40,"coordinates":323},[324,325],9.99302,53.55073,{"lat":325,"lon":324},{"facility":328,"status":11,"city":329,"state":11,"zip":330,"country":301,"countryCode":303,"cosmosGeoPoint":331,"geoPoint":335,"contacts":11},"Ludwig Maximilians-Universitaet Muenchen","München","80336",{"type":40,"coordinates":332},[333,334],13.31243,51.60698,{"lat":334,"lon":333},{"facility":337,"status":11,"city":338,"state":11,"zip":339,"country":301,"countryCode":303,"cosmosGeoPoint":340,"geoPoint":344,"contacts":11},"FOCUS Clinical Drug Development GmbH","Neuss","41460",{"type":40,"coordinates":341},[342,343],6.68504,51.19807,{"lat":343,"lon":342},{"facility":346,"status":11,"city":347,"state":348,"zip":349,"country":350,"countryCode":351,"cosmosGeoPoint":352,"geoPoint":356,"contacts":11},"Synexus Thames Valley Clinical Research Centre","Reading","Berks","RG2 0TG","United Kingdom","UK",{"type":40,"coordinates":353},[354,355],-0.97113,51.45625,{"lat":355,"lon":354},{"facility":358,"status":11,"city":359,"state":360,"zip":361,"country":350,"countryCode":351,"cosmosGeoPoint":362,"geoPoint":366,"contacts":11},"Synexus Lancashire Clinical Research Centre","Chorley","Lancashire","PR7 7NA",{"type":40,"coordinates":363},[364,365],-2.61667,53.65,{"lat":365,"lon":364},{"facility":368,"status":11,"city":369,"state":11,"zip":370,"country":350,"countryCode":351,"cosmosGeoPoint":371,"geoPoint":375,"contacts":11},"Synexus Scotland Clinical Research Centre","Glasgow","G20 0SP",{"type":40,"coordinates":372},[373,374],-4.25763,55.86515,{"lat":374,"lon":373},{"facility":377,"status":11,"city":378,"state":11,"zip":379,"country":350,"countryCode":351,"cosmosGeoPoint":380,"geoPoint":384,"contacts":11},"Synexus, Merseyside Clinical Research Centre","Liverpool","L22 0LG",{"type":40,"coordinates":381},[382,383],-2.97794,53.41058,{"lat":383,"lon":382},{"facility":386,"status":11,"city":387,"state":11,"zip":388,"country":350,"countryCode":351,"cosmosGeoPoint":389,"geoPoint":393,"contacts":11},"William Harvey Research Institute,","London","EC1M 6BQ",{"type":40,"coordinates":390},[391,392],-0.12574,51.50853,{"lat":392,"lon":391},{"type":395,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100151512","phase-4-a-multi-national-study-to-assess-how-effective-and-safe-the-smoking-cessation-medicine-varenicline-is-in-smokers-who-have-already-tried-varenicline-in-the-past-as-a-prescription-medicine-from-their-usual-healthcare-provider-100151512",true,"NCT01244061","A Multi-National Study To Assess How Effective And Safe The Smoking Cessation Medicine Varenicline Is In Smokers Who Have Already Tried Varenicline In The Past As A Prescription Medicine From Their Usual Healthcare Provider","A Phase 4 Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Evaluating The Efficacy And Safety Of Re-Treatment With Varenicline In Subjects Who Are Currently Smoking, And Who Have Previously Taken Varenicline","Inclusion Criteria:\n\n* Smokers aged 18 years or above and wanting to stop smoking\n* Smokers who have smoked an average of at least 10 cigarettes per day over the last 4 weeks\n* Smokers who have tried before to stop smoking at least once with varenicline, and who took varenicline for at least 2 weeks\n* The last attempt to stop smoking must be at least 3 months before entering the study\n\nExclusion Criteria:\n\n* Individuals who have not tolerated varenicline well previously, or who have a current or prior medical or psychiatric history that would make entry into the trial inadvisable\n* Individuals who have previously participated in clinical trials of varenicline\n* Individuals who have been participating in another smoking cessation trial within the last 3 months, or other drug trial within the last 30 days",false,"ALL","18 Years",{"count":407,"type":408},498,"ACTUAL","INTERVENTIONAL",[411],"PHASE4","The main purpose of this study is to compare the effectiveness and safety of the re-treatment of smokers with varenicline with placebo for smoking cessation during the last 4 weeks of a 12 week course of treatment. The study will also assess whether smokers remain abstinent at Week 24 (12 weeks after the end of treatment) and Week 52 (40 weeks after the end of treatment).",[414],"Smoking Cessation","COMPLETED","2014-05-20",{"date":418,"type":419},"2014-06-09","ESTIMATED",{"date":421,"type":11},"2010-12",{"date":423,"type":408},"2012-11",{"name":5,"class":6},37]