[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100265699":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":39,"centralContacts":38,"locations":43,"responsibleParty":1406,"collaborators":38,"id":1408,"slug":1409,"hasResults":1410,"nctId":1411,"briefTitle":1412,"officialTitle":1413,"acronym":1414,"eligibilityCriteria":1415,"healthyVolunteers":1416,"sex":1417,"minAge":1418,"maxAge":38,"enrollmentInfo":1419,"targetDuration":38,"studyType":1422,"phases":1423,"briefSummary":1425,"conditions":1426,"keywords":38,"overallStatus":1428,"whyStopped":38,"lastUpdateSubmitDate":1429,"lastUpdatePostDateStruct":1430,"startDateStruct":1432,"completionDateStruct":1434,"leadSponsor":1436,"locationsCount":1437},{"fullName":5,"class":6},"Sanofi","INDUSTRY",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Toujeo","EXPERIMENTAL","Toujeo® (Insulin glargine, 300 U\u002FmL) subcutaneous (SC) injection once daily up to Week 24 on top of non-insulin antidiabetic treatment.",[13,14],"Drug: Insulin glargine, 300U\u002FmL","Drug: Non-insulin anti-diabetic treatment",{"label":16,"type":17,"description":18,"interventionNames":19},"Tresiba","ACTIVE_COMPARATOR","Tresiba® (Insulin Degludec, 100 U\u002FmL) SC injection once daily up to Week 24 on top of non-insulin antidiabetic treatment .",[20,14],"Drug: Insulin degludec, 100 U\u002FmL",[22,29,34],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DRUG","Insulin glargine, 300U\u002FmL","Self-administered by subcutaneous (SC) injection in the evening using a pre-filled pen. Dose titration to achieve fasting self-monitored plasma glucose (SMPG) from 80 to 100 mg\u002FdL (4.4 to 5.6 mmol\u002FL).",[9],[28,9],"HOE901-U300",{"type":23,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"Insulin degludec, 100 U\u002FmL","Self-administered by subcutaneous (SC) injection in the evening using a pre-filled pen. Dose titration to achieve fasting self-monitored plasma glucose (SMPG) from 80 to 100 mg\u002FdL (4.4 to 5.6 mmol\u002FL).\n\nRoute of administration: subcutaneous",[16],[16],{"type":23,"name":35,"description":36,"armGroupLabels":37,"otherNames":38},"Non-insulin anti-diabetic treatment","Background therapy: Oral Anti diabetics Drugs (OADs), Glucagon-like peptide-1 (GLP-1) receptor agonist.",[9,16],null,[40],{"name":41,"affiliation":5,"role":42},"Clinical Sciences & Operations","STUDY_DIRECTOR",[44,57,67,77,86,95,104,113,122,131,140,149,158,168,177,186,195,200,209,219,228,237,246,256,265,275,285,294,300,309,319,329,338,348,354,363,373,383,393,399,409,419,428,437,446,456,462,472,481,491,500,509,518,527,536,545,554,563,573,579,588,594,600,606,615,624,633,642,651,660,670,679,688,697,707,718,724,729,740,745,753,762,771,780,789,798,804,810,819,830,839,848,857,868,877,886,895,904,913,924,933,938,943,954,960,966,975,986,991,996,1004,1012,1020,1025,1034,1045,1053,1062,1071,1080,1089,1097,1102,1107,1116,1125,1134,1145,1151,1160,1166,1171,1180,1189,1198,1206,1211,1220,1226,1231,1241,1249,1254,1265,1274,1283,1292,1301,1312,1321,1332,1341,1352,1361,1370,1379,1388,1397],{"facility":45,"status":38,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":38},"Investigational Site Number 840038","Sheffield","Alabama","35660","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-87.69864,34.76509,{"lat":55,"lon":54},{"facility":58,"status":38,"city":59,"state":60,"zip":61,"country":49,"countryCode":50,"cosmosGeoPoint":62,"geoPoint":66,"contacts":38},"Investigational Site Number 840066","Phoenix","Arizona","85020",{"type":52,"coordinates":63},[64,65],-112.07404,33.44838,{"lat":65,"lon":64},{"facility":68,"status":38,"city":69,"state":70,"zip":71,"country":49,"countryCode":50,"cosmosGeoPoint":72,"geoPoint":76,"contacts":38},"Investigational Site Number 840051","Anaheim","California","92801",{"type":52,"coordinates":73},[74,75],-117.9145,33.83529,{"lat":75,"lon":74},{"facility":78,"status":38,"city":79,"state":70,"zip":80,"country":49,"countryCode":50,"cosmosGeoPoint":81,"geoPoint":85,"contacts":38},"Investigational Site Number 840081","Chino","91710",{"type":52,"coordinates":82},[83,84],-117.68894,34.01223,{"lat":84,"lon":83},{"facility":87,"status":38,"city":88,"state":70,"zip":89,"country":49,"countryCode":50,"cosmosGeoPoint":90,"geoPoint":94,"contacts":38},"Investigational Site Number 840016","Huntington Park","90255",{"type":52,"coordinates":91},[92,93],-118.22507,33.98168,{"lat":93,"lon":92},{"facility":96,"status":38,"city":97,"state":70,"zip":98,"country":49,"countryCode":50,"cosmosGeoPoint":99,"geoPoint":103,"contacts":38},"Investigational Site Number 840002","La Jolla","92037",{"type":52,"coordinates":100},[101,102],-117.2742,32.84727,{"lat":102,"lon":101},{"facility":105,"status":38,"city":106,"state":70,"zip":107,"country":49,"countryCode":50,"cosmosGeoPoint":108,"geoPoint":112,"contacts":38},"Investigational Site Number 840091","Los Angeles","90017",{"type":52,"coordinates":109},[110,111],-118.24368,34.05223,{"lat":111,"lon":110},{"facility":114,"status":38,"city":115,"state":70,"zip":116,"country":49,"countryCode":50,"cosmosGeoPoint":117,"geoPoint":121,"contacts":38},"Investigational Site Number 840058","Northridge","91324",{"type":52,"coordinates":118},[119,120],-118.53675,34.22834,{"lat":120,"lon":119},{"facility":123,"status":38,"city":124,"state":70,"zip":125,"country":49,"countryCode":50,"cosmosGeoPoint":126,"geoPoint":130,"contacts":38},"Investigational Site Number 840021","Palm Springs","92262",{"type":52,"coordinates":127},[128,129],-116.54529,33.8303,{"lat":129,"lon":128},{"facility":132,"status":38,"city":133,"state":70,"zip":134,"country":49,"countryCode":50,"cosmosGeoPoint":135,"geoPoint":139,"contacts":38},"Investigational Site Number 840087","Santa Ana","92704",{"type":52,"coordinates":136},[137,138],-117.86783,33.74557,{"lat":138,"lon":137},{"facility":141,"status":38,"city":142,"state":70,"zip":143,"country":49,"countryCode":50,"cosmosGeoPoint":144,"geoPoint":148,"contacts":38},"Investigational Site Number 840030","Torrance","90505",{"type":52,"coordinates":145},[146,147],-118.34063,33.83585,{"lat":147,"lon":146},{"facility":150,"status":38,"city":151,"state":70,"zip":152,"country":49,"countryCode":50,"cosmosGeoPoint":153,"geoPoint":157,"contacts":38},"Investigational Site Number 840065","Van Nuys","91405",{"type":52,"coordinates":154},[155,156],-118.44897,34.18667,{"lat":156,"lon":155},{"facility":159,"status":38,"city":160,"state":161,"zip":162,"country":49,"countryCode":50,"cosmosGeoPoint":163,"geoPoint":167,"contacts":38},"Investigational Site Number 840075","Bradenton","Florida","34201",{"type":52,"coordinates":164},[165,166],-82.57482,27.49893,{"lat":166,"lon":165},{"facility":169,"status":38,"city":170,"state":161,"zip":171,"country":49,"countryCode":50,"cosmosGeoPoint":172,"geoPoint":176,"contacts":38},"Investigational Site Number 840076","New Port Richey","34652",{"type":52,"coordinates":173},[174,175],-82.71927,28.24418,{"lat":175,"lon":174},{"facility":178,"status":38,"city":179,"state":161,"zip":180,"country":49,"countryCode":50,"cosmosGeoPoint":181,"geoPoint":185,"contacts":38},"Investigational Site Number 840026","Ocoee","34761",{"type":52,"coordinates":182},[183,184],-81.54396,28.56917,{"lat":184,"lon":183},{"facility":187,"status":38,"city":188,"state":161,"zip":189,"country":49,"countryCode":50,"cosmosGeoPoint":190,"geoPoint":194,"contacts":38},"Investigational Site Number 840052","Palm Harbor","34684",{"type":52,"coordinates":191},[192,193],-82.76371,28.07807,{"lat":193,"lon":192},{"facility":196,"status":38,"city":188,"state":161,"zip":189,"country":49,"countryCode":50,"cosmosGeoPoint":197,"geoPoint":199,"contacts":38},"Investigational Site Number 840080",{"type":52,"coordinates":198},[192,193],{"lat":193,"lon":192},{"facility":201,"status":38,"city":202,"state":161,"zip":203,"country":49,"countryCode":50,"cosmosGeoPoint":204,"geoPoint":208,"contacts":38},"Investigational Site Number 840018","Port Charlotte","33952",{"type":52,"coordinates":205},[206,207],-82.09064,26.97617,{"lat":207,"lon":206},{"facility":210,"status":38,"city":211,"state":212,"zip":213,"country":49,"countryCode":50,"cosmosGeoPoint":214,"geoPoint":218,"contacts":38},"Investigational Site Number 840071","Lawrenceville","Georgia","30046",{"type":52,"coordinates":215},[216,217],-83.98796,33.95621,{"lat":217,"lon":216},{"facility":220,"status":38,"city":221,"state":212,"zip":222,"country":49,"countryCode":50,"cosmosGeoPoint":223,"geoPoint":227,"contacts":38},"Investigational Site Number 840085","Roswell","30076",{"type":52,"coordinates":224},[225,226],-84.36159,34.02316,{"lat":226,"lon":225},{"facility":229,"status":38,"city":230,"state":212,"zip":231,"country":49,"countryCode":50,"cosmosGeoPoint":232,"geoPoint":236,"contacts":38},"Investigational Site Number 840072","Statesboro","30461",{"type":52,"coordinates":233},[234,235],-81.78317,32.44879,{"lat":235,"lon":234},{"facility":238,"status":38,"city":239,"state":212,"zip":240,"country":49,"countryCode":50,"cosmosGeoPoint":241,"geoPoint":245,"contacts":38},"Investigational Site Number 840039","Stockbridge","30281",{"type":52,"coordinates":242},[243,244],-84.23381,33.54428,{"lat":244,"lon":243},{"facility":247,"status":38,"city":248,"state":249,"zip":250,"country":49,"countryCode":50,"cosmosGeoPoint":251,"geoPoint":255,"contacts":38},"Investigational Site Number 840036","Arlington Heights","Illinois","60005",{"type":52,"coordinates":252},[253,254],-87.98063,42.08836,{"lat":254,"lon":253},{"facility":257,"status":38,"city":258,"state":249,"zip":259,"country":49,"countryCode":50,"cosmosGeoPoint":260,"geoPoint":264,"contacts":38},"Investigational Site Number 840010","Chicago","60616",{"type":52,"coordinates":261},[262,263],-87.65005,41.85003,{"lat":263,"lon":262},{"facility":266,"status":38,"city":267,"state":268,"zip":269,"country":49,"countryCode":50,"cosmosGeoPoint":270,"geoPoint":274,"contacts":38},"Investigational Site Number 840005","Avon","Indiana","46123",{"type":52,"coordinates":271},[272,273],-86.39972,39.76282,{"lat":273,"lon":272},{"facility":276,"status":38,"city":277,"state":278,"zip":279,"country":49,"countryCode":50,"cosmosGeoPoint":280,"geoPoint":284,"contacts":38},"Investigational Site Number 840063","Council Bluffs","Iowa","51501",{"type":52,"coordinates":281},[282,283],-95.86083,41.26194,{"lat":283,"lon":282},{"facility":286,"status":38,"city":287,"state":278,"zip":288,"country":49,"countryCode":50,"cosmosGeoPoint":289,"geoPoint":293,"contacts":38},"Investigational Site Number 840098","Des Moines","50134",{"type":52,"coordinates":290},[291,292],-93.60911,41.60054,{"lat":292,"lon":291},{"facility":295,"status":38,"city":287,"state":278,"zip":296,"country":49,"countryCode":50,"cosmosGeoPoint":297,"geoPoint":299,"contacts":38},"Investigational Site Number 840101","50314",{"type":52,"coordinates":298},[291,292],{"lat":292,"lon":291},{"facility":301,"status":38,"city":302,"state":278,"zip":303,"country":49,"countryCode":50,"cosmosGeoPoint":304,"geoPoint":308,"contacts":38},"Investigational Site Number 840096","West Des Moines","50266",{"type":52,"coordinates":305},[306,307],-93.71133,41.57721,{"lat":307,"lon":306},{"facility":310,"status":38,"city":311,"state":312,"zip":313,"country":49,"countryCode":50,"cosmosGeoPoint":314,"geoPoint":318,"contacts":38},"Investigational Site Number 840061","Paris","Kentucky","40361",{"type":52,"coordinates":315},[316,317],-84.25299,38.2098,{"lat":317,"lon":316},{"facility":320,"status":38,"city":321,"state":322,"zip":323,"country":49,"countryCode":50,"cosmosGeoPoint":324,"geoPoint":328,"contacts":38},"Investigational Site Number 840011","Hyattsville","Maryland","20782",{"type":52,"coordinates":325},[326,327],-76.94553,38.95594,{"lat":327,"lon":326},{"facility":330,"status":38,"city":331,"state":322,"zip":332,"country":49,"countryCode":50,"cosmosGeoPoint":333,"geoPoint":337,"contacts":38},"Investigational Site Number 840001","Rockville","20852",{"type":52,"coordinates":334},[335,336],-77.15276,39.084,{"lat":336,"lon":335},{"facility":339,"status":38,"city":340,"state":341,"zip":342,"country":49,"countryCode":50,"cosmosGeoPoint":343,"geoPoint":347,"contacts":38},"Investigational Site Number 840041","Flint","Michigan","48504",{"type":52,"coordinates":344},[345,346],-83.68746,43.01253,{"lat":346,"lon":345},{"facility":349,"status":38,"city":340,"state":341,"zip":350,"country":49,"countryCode":50,"cosmosGeoPoint":351,"geoPoint":353,"contacts":38},"Investigational Site Number 840057","48532",{"type":52,"coordinates":352},[345,346],{"lat":346,"lon":345},{"facility":355,"status":38,"city":356,"state":341,"zip":357,"country":49,"countryCode":50,"cosmosGeoPoint":358,"geoPoint":362,"contacts":38},"Investigational Site Number 840033","Troy","48085",{"type":52,"coordinates":359},[360,361],-83.14993,42.60559,{"lat":361,"lon":360},{"facility":364,"status":38,"city":365,"state":366,"zip":367,"country":49,"countryCode":50,"cosmosGeoPoint":368,"geoPoint":372,"contacts":38},"Investigational Site Number 840084","Olive Branch","Mississippi","38654",{"type":52,"coordinates":369},[370,371],-89.82953,34.96176,{"lat":371,"lon":370},{"facility":374,"status":38,"city":375,"state":376,"zip":377,"country":49,"countryCode":50,"cosmosGeoPoint":378,"geoPoint":382,"contacts":38},"Investigational Site Number 840048","Chesterfield","Missouri","63017",{"type":52,"coordinates":379},[380,381],-90.57707,38.66311,{"lat":381,"lon":380},{"facility":384,"status":38,"city":385,"state":386,"zip":387,"country":49,"countryCode":50,"cosmosGeoPoint":388,"geoPoint":392,"contacts":38},"Investigational Site Number 840023","Las Vegas","Nevada","89117",{"type":52,"coordinates":389},[390,391],-115.13722,36.17497,{"lat":391,"lon":390},{"facility":394,"status":38,"city":385,"state":386,"zip":395,"country":49,"countryCode":50,"cosmosGeoPoint":396,"geoPoint":398,"contacts":38},"Investigational Site Number 840045","89128",{"type":52,"coordinates":397},[390,391],{"lat":391,"lon":390},{"facility":400,"status":38,"city":401,"state":402,"zip":403,"country":49,"countryCode":50,"cosmosGeoPoint":404,"geoPoint":408,"contacts":38},"Investigational Site Number 840031","Linden","New Jersey","07036",{"type":52,"coordinates":405},[406,407],-74.24459,40.62205,{"lat":407,"lon":406},{"facility":410,"status":38,"city":411,"state":412,"zip":413,"country":49,"countryCode":50,"cosmosGeoPoint":414,"geoPoint":418,"contacts":38},"Investigational Site Number 840060","Hickory","North Carolina","28601",{"type":52,"coordinates":415},[416,417],-81.3412,35.73319,{"lat":417,"lon":416},{"facility":420,"status":38,"city":421,"state":412,"zip":422,"country":49,"countryCode":50,"cosmosGeoPoint":423,"geoPoint":427,"contacts":38},"Investigational Site Number 840064","Morganton","28655",{"type":52,"coordinates":424},[425,426],-81.68482,35.74541,{"lat":426,"lon":425},{"facility":429,"status":38,"city":430,"state":412,"zip":431,"country":49,"countryCode":50,"cosmosGeoPoint":432,"geoPoint":436,"contacts":38},"Investigational Site Number 840043","Wilmington","28401",{"type":52,"coordinates":433},[434,435],-77.94604,34.23556,{"lat":435,"lon":434},{"facility":438,"status":38,"city":439,"state":412,"zip":440,"country":49,"countryCode":50,"cosmosGeoPoint":441,"geoPoint":445,"contacts":38},"Investigational Site Number 840082","Winston-Salem","27103",{"type":52,"coordinates":442},[443,444],-80.24422,36.09986,{"lat":444,"lon":443},{"facility":447,"status":38,"city":448,"state":449,"zip":450,"country":49,"countryCode":50,"cosmosGeoPoint":451,"geoPoint":455,"contacts":38},"Investigational Site Number 840025","Oklahoma City","Oklahoma","73104",{"type":52,"coordinates":452},[453,454],-97.51643,35.46756,{"lat":454,"lon":453},{"facility":457,"status":38,"city":448,"state":449,"zip":458,"country":49,"countryCode":50,"cosmosGeoPoint":459,"geoPoint":461,"contacts":38},"Investigational Site Number 840022","73112",{"type":52,"coordinates":460},[453,454],{"lat":454,"lon":453},{"facility":463,"status":38,"city":464,"state":465,"zip":466,"country":49,"countryCode":50,"cosmosGeoPoint":467,"geoPoint":471,"contacts":38},"Investigational Site Number 840029","Beaver","Pennsylvania","15009",{"type":52,"coordinates":468},[469,470],-80.30478,40.69534,{"lat":470,"lon":469},{"facility":473,"status":38,"city":474,"state":465,"zip":475,"country":49,"countryCode":50,"cosmosGeoPoint":476,"geoPoint":480,"contacts":38},"Investigational Site Number 840056","Downingtown","19335",{"type":52,"coordinates":477},[478,479],-75.70327,40.0065,{"lat":479,"lon":478},{"facility":482,"status":38,"city":483,"state":484,"zip":485,"country":49,"countryCode":50,"cosmosGeoPoint":486,"geoPoint":490,"contacts":38},"Investigational Site Number 840093","Anderson","South Carolina","29621",{"type":52,"coordinates":487},[488,489],-82.65013,34.50344,{"lat":489,"lon":488},{"facility":492,"status":38,"city":493,"state":484,"zip":494,"country":49,"countryCode":50,"cosmosGeoPoint":495,"geoPoint":499,"contacts":38},"Investigational Site Number 840097","Greenville","29605",{"type":52,"coordinates":496},[497,498],-82.39401,34.85262,{"lat":498,"lon":497},{"facility":501,"status":38,"city":502,"state":484,"zip":503,"country":49,"countryCode":50,"cosmosGeoPoint":504,"geoPoint":508,"contacts":38},"Investigational Site Number 840070","Greer","29651",{"type":52,"coordinates":505},[506,507],-82.22706,34.93873,{"lat":507,"lon":506},{"facility":510,"status":38,"city":511,"state":484,"zip":512,"country":49,"countryCode":50,"cosmosGeoPoint":513,"geoPoint":517,"contacts":38},"Investigational Site Number 840044","North Myrtle Beach","29582",{"type":52,"coordinates":514},[515,516],-78.68002,33.81601,{"lat":516,"lon":515},{"facility":519,"status":38,"city":520,"state":484,"zip":521,"country":49,"countryCode":50,"cosmosGeoPoint":522,"geoPoint":526,"contacts":38},"Investigational Site Number 840069","Simpsonville","29681",{"type":52,"coordinates":523},[524,525],-82.25428,34.73706,{"lat":525,"lon":524},{"facility":528,"status":38,"city":529,"state":530,"zip":38,"country":49,"countryCode":50,"cosmosGeoPoint":531,"geoPoint":535,"contacts":38},"Investigational Site Number 840079","Bristol","Tennessee",{"type":52,"coordinates":532},[533,534],-82.18874,36.59511,{"lat":534,"lon":533},{"facility":537,"status":38,"city":538,"state":530,"zip":539,"country":49,"countryCode":50,"cosmosGeoPoint":540,"geoPoint":544,"contacts":38},"Investigational Site Number 840006","Chattanooga","37404",{"type":52,"coordinates":541},[542,543],-85.30968,35.04563,{"lat":543,"lon":542},{"facility":546,"status":38,"city":547,"state":530,"zip":548,"country":49,"countryCode":50,"cosmosGeoPoint":549,"geoPoint":553,"contacts":38},"Investigational Site Number 840088","Knoxville","37912",{"type":52,"coordinates":550},[551,552],-83.92074,35.96064,{"lat":552,"lon":551},{"facility":555,"status":38,"city":556,"state":530,"zip":557,"country":49,"countryCode":50,"cosmosGeoPoint":558,"geoPoint":562,"contacts":38},"Investigational Site Number 840077","New Tazewell","37825",{"type":52,"coordinates":559},[560,561],-83.59963,36.44258,{"lat":561,"lon":560},{"facility":564,"status":38,"city":565,"state":566,"zip":567,"country":49,"countryCode":50,"cosmosGeoPoint":568,"geoPoint":572,"contacts":38},"Investigational Site Number 840007","Dallas","Texas","75230",{"type":52,"coordinates":569},[570,571],-96.80667,32.78306,{"lat":571,"lon":570},{"facility":574,"status":38,"city":565,"state":566,"zip":575,"country":49,"countryCode":50,"cosmosGeoPoint":576,"geoPoint":578,"contacts":38},"Investigational Site Number 840086","75231",{"type":52,"coordinates":577},[570,571],{"lat":571,"lon":570},{"facility":580,"status":38,"city":581,"state":566,"zip":582,"country":49,"countryCode":50,"cosmosGeoPoint":583,"geoPoint":587,"contacts":38},"Investigational Site Number 840027","Houston","77061",{"type":52,"coordinates":584},[585,586],-95.36327,29.76328,{"lat":586,"lon":585},{"facility":589,"status":38,"city":581,"state":566,"zip":590,"country":49,"countryCode":50,"cosmosGeoPoint":591,"geoPoint":593,"contacts":38},"Investigational Site Number 840004","77083-4436",{"type":52,"coordinates":592},[585,586],{"lat":586,"lon":585},{"facility":595,"status":38,"city":581,"state":566,"zip":596,"country":49,"countryCode":50,"cosmosGeoPoint":597,"geoPoint":599,"contacts":38},"Investigational Site Number 840040","77090",{"type":52,"coordinates":598},[585,586],{"lat":586,"lon":585},{"facility":601,"status":38,"city":581,"state":566,"zip":602,"country":49,"countryCode":50,"cosmosGeoPoint":603,"geoPoint":605,"contacts":38},"Investigational Site Number 840046","77095",{"type":52,"coordinates":604},[585,586],{"lat":586,"lon":585},{"facility":607,"status":38,"city":608,"state":566,"zip":609,"country":49,"countryCode":50,"cosmosGeoPoint":610,"geoPoint":614,"contacts":38},"Investigational Site Number 840054","Hurst","76054",{"type":52,"coordinates":611},[612,613],-97.17057,32.82346,{"lat":613,"lon":612},{"facility":616,"status":38,"city":617,"state":566,"zip":618,"country":49,"countryCode":50,"cosmosGeoPoint":619,"geoPoint":623,"contacts":38},"Investigational Site Number 840017","Mesquite","75149",{"type":52,"coordinates":620},[621,622],-96.59916,32.7668,{"lat":622,"lon":621},{"facility":625,"status":38,"city":626,"state":566,"zip":627,"country":49,"countryCode":50,"cosmosGeoPoint":628,"geoPoint":632,"contacts":38},"Investigational Site Number 840008","Missouri City","77459",{"type":52,"coordinates":629},[630,631],-95.53772,29.61857,{"lat":631,"lon":630},{"facility":634,"status":38,"city":635,"state":566,"zip":636,"country":49,"countryCode":50,"cosmosGeoPoint":637,"geoPoint":641,"contacts":38},"Investigational Site Number 840094","San Antonio","78229-3907",{"type":52,"coordinates":638},[639,640],-98.49363,29.42412,{"lat":640,"lon":639},{"facility":643,"status":38,"city":644,"state":566,"zip":645,"country":49,"countryCode":50,"cosmosGeoPoint":646,"geoPoint":650,"contacts":38},"Investigational Site Number 840009","Sugar Land","77478",{"type":52,"coordinates":647},[648,649],-95.63495,29.61968,{"lat":649,"lon":648},{"facility":652,"status":38,"city":653,"state":566,"zip":654,"country":49,"countryCode":50,"cosmosGeoPoint":655,"geoPoint":659,"contacts":38},"Investigational Site Number 840053","Waco","76710",{"type":52,"coordinates":656},[657,658],-97.14667,31.54933,{"lat":658,"lon":657},{"facility":661,"status":38,"city":662,"state":663,"zip":664,"country":49,"countryCode":50,"cosmosGeoPoint":665,"geoPoint":669,"contacts":38},"Investigational Site Number 840095","Ogden","Utah","84405",{"type":52,"coordinates":666},[667,668],-111.97383,41.223,{"lat":668,"lon":667},{"facility":671,"status":38,"city":672,"state":663,"zip":673,"country":49,"countryCode":50,"cosmosGeoPoint":674,"geoPoint":678,"contacts":38},"Investigational Site Number 840032","Salt Lake City","84102",{"type":52,"coordinates":675},[676,677],-111.89105,40.76078,{"lat":677,"lon":676},{"facility":680,"status":38,"city":681,"state":682,"zip":38,"country":49,"countryCode":50,"cosmosGeoPoint":683,"geoPoint":687,"contacts":38},"Investigational Site Number 840024","Norfolk","Virginia",{"type":52,"coordinates":684},[685,686],-76.28522,36.84681,{"lat":686,"lon":685},{"facility":689,"status":38,"city":690,"state":682,"zip":691,"country":49,"countryCode":50,"cosmosGeoPoint":692,"geoPoint":696,"contacts":38},"Investigational Site Number 840020","Richmond","23219",{"type":52,"coordinates":693},[694,695],-77.46026,37.55376,{"lat":695,"lon":694},{"facility":698,"status":38,"city":699,"state":700,"zip":701,"country":49,"countryCode":50,"cosmosGeoPoint":702,"geoPoint":706,"contacts":38},"Investigational Site Number 840012","Renton","Washington","98055",{"type":52,"coordinates":703},[704,705],-122.21707,47.48288,{"lat":705,"lon":704},{"facility":708,"status":38,"city":709,"state":38,"zip":710,"country":711,"countryCode":712,"cosmosGeoPoint":713,"geoPoint":717,"contacts":38},"Investigational Site Number 100001","Sofia","1431","Bulgaria","BG",{"type":52,"coordinates":714},[715,716],23.32415,42.69751,{"lat":716,"lon":715},{"facility":719,"status":38,"city":709,"state":38,"zip":720,"country":711,"countryCode":712,"cosmosGeoPoint":721,"geoPoint":723,"contacts":38},"Investigational Site Number 100002","1505",{"type":52,"coordinates":722},[715,716],{"lat":716,"lon":715},{"facility":725,"status":38,"city":709,"state":38,"zip":38,"country":711,"countryCode":712,"cosmosGeoPoint":726,"geoPoint":728,"contacts":38},"Investigational Site Number 100003",{"type":52,"coordinates":727},[715,716],{"lat":716,"lon":715},{"facility":730,"status":38,"city":731,"state":38,"zip":732,"country":733,"countryCode":734,"cosmosGeoPoint":735,"geoPoint":739,"contacts":38},"Investigational Site Number 191001","Rijeka","51000","Croatia","HR",{"type":52,"coordinates":736},[737,738],14.44241,45.32673,{"lat":738,"lon":737},{"facility":741,"status":38,"city":731,"state":38,"zip":732,"country":733,"countryCode":734,"cosmosGeoPoint":742,"geoPoint":744,"contacts":38},"Investigational Site Number 191002",{"type":52,"coordinates":743},[737,738],{"lat":738,"lon":737},{"facility":746,"status":38,"city":747,"state":38,"zip":38,"country":733,"countryCode":734,"cosmosGeoPoint":748,"geoPoint":752,"contacts":38},"Investigational Site Number 191003","Zagreb",{"type":52,"coordinates":749},[750,751],15.97798,45.81444,{"lat":751,"lon":750},{"facility":754,"status":38,"city":755,"state":38,"zip":38,"country":756,"countryCode":38,"cosmosGeoPoint":757,"geoPoint":761,"contacts":38},"Investigational Site Number 203009","Hlučín","Czechia",{"type":52,"coordinates":758},[759,760],18.19196,49.89795,{"lat":760,"lon":759},{"facility":763,"status":38,"city":764,"state":38,"zip":765,"country":756,"countryCode":38,"cosmosGeoPoint":766,"geoPoint":770,"contacts":38},"Investigational Site Number 203006","Jílové u Prahy","25401",{"type":52,"coordinates":767},[768,769],14.49333,49.89545,{"lat":769,"lon":768},{"facility":772,"status":38,"city":773,"state":38,"zip":774,"country":756,"countryCode":38,"cosmosGeoPoint":775,"geoPoint":779,"contacts":38},"Investigational Site Number 203005","Liberec","46001",{"type":52,"coordinates":776},[777,778],15.05619,50.76711,{"lat":778,"lon":777},{"facility":781,"status":38,"city":782,"state":38,"zip":783,"country":756,"countryCode":38,"cosmosGeoPoint":784,"geoPoint":788,"contacts":38},"Investigational Site Number 203001","Pardubice","53002",{"type":52,"coordinates":785},[786,787],15.77659,50.04075,{"lat":787,"lon":786},{"facility":790,"status":38,"city":791,"state":38,"zip":792,"country":756,"countryCode":38,"cosmosGeoPoint":793,"geoPoint":797,"contacts":38},"Investigational Site Number 203007","Prague","11000",{"type":52,"coordinates":794},[795,796],14.42076,50.08804,{"lat":796,"lon":795},{"facility":799,"status":38,"city":791,"state":38,"zip":800,"country":756,"countryCode":38,"cosmosGeoPoint":801,"geoPoint":803,"contacts":38},"Investigational Site Number 203008","12808",{"type":52,"coordinates":802},[795,796],{"lat":796,"lon":795},{"facility":805,"status":38,"city":791,"state":38,"zip":806,"country":756,"countryCode":38,"cosmosGeoPoint":807,"geoPoint":809,"contacts":38},"Investigational Site Number 203002","18100",{"type":52,"coordinates":808},[795,796],{"lat":796,"lon":795},{"facility":811,"status":38,"city":812,"state":38,"zip":813,"country":756,"countryCode":38,"cosmosGeoPoint":814,"geoPoint":818,"contacts":38},"Investigational Site Number 203004","Vsetín","75501",{"type":52,"coordinates":815},[816,817],17.99619,49.33871,{"lat":817,"lon":816},{"facility":820,"status":38,"city":821,"state":38,"zip":822,"country":823,"countryCode":824,"cosmosGeoPoint":825,"geoPoint":829,"contacts":38},"Investigational Site Number 208003","Aarhus","8000","Denmark","DK",{"type":52,"coordinates":826},[827,828],10.21076,56.15674,{"lat":828,"lon":827},{"facility":831,"status":38,"city":832,"state":38,"zip":833,"country":823,"countryCode":824,"cosmosGeoPoint":834,"geoPoint":838,"contacts":38},"Investigational Site Number 208002","Hillerød","3400",{"type":52,"coordinates":835},[836,837],12.30081,55.92791,{"lat":837,"lon":836},{"facility":840,"status":38,"city":841,"state":38,"zip":842,"country":823,"countryCode":824,"cosmosGeoPoint":843,"geoPoint":847,"contacts":38},"Investigational Site Number 208001","København NV","2400",{"type":52,"coordinates":844},[845,846],12.52343,55.71258,{"lat":846,"lon":845},{"facility":849,"status":38,"city":850,"state":38,"zip":851,"country":823,"countryCode":824,"cosmosGeoPoint":852,"geoPoint":856,"contacts":38},"Investigational Site Number 208004","Odense","5000",{"type":52,"coordinates":853},[854,855],10.38831,55.39594,{"lat":855,"lon":854},{"facility":858,"status":38,"city":859,"state":38,"zip":860,"country":861,"countryCode":862,"cosmosGeoPoint":863,"geoPoint":867,"contacts":38},"Investigational Site Number 250002","La Roche-sur-Yon","85025","France","FR",{"type":52,"coordinates":864},[865,866],-1.42757,46.66974,{"lat":866,"lon":865},{"facility":869,"status":38,"city":870,"state":38,"zip":871,"country":861,"countryCode":862,"cosmosGeoPoint":872,"geoPoint":876,"contacts":38},"Investigational Site Number 250003","La Rochelle","17019",{"type":52,"coordinates":873},[874,875],-1.15222,46.16308,{"lat":875,"lon":874},{"facility":878,"status":38,"city":879,"state":38,"zip":880,"country":861,"countryCode":862,"cosmosGeoPoint":881,"geoPoint":885,"contacts":38},"Investigational Site Number 250001","Nantes","44093",{"type":52,"coordinates":882},[883,884],-1.55336,47.21725,{"lat":884,"lon":883},{"facility":887,"status":38,"city":888,"state":38,"zip":889,"country":861,"countryCode":862,"cosmosGeoPoint":890,"geoPoint":894,"contacts":38},"Investigational Site Number 250006","Nîmes","30029",{"type":52,"coordinates":891},[892,893],4.35788,43.83665,{"lat":893,"lon":892},{"facility":896,"status":38,"city":897,"state":38,"zip":898,"country":861,"countryCode":862,"cosmosGeoPoint":899,"geoPoint":903,"contacts":38},"Investigational Site Number 250005","Poitiers","86021",{"type":52,"coordinates":900},[901,902],0.34348,46.58261,{"lat":902,"lon":901},{"facility":905,"status":38,"city":906,"state":38,"zip":907,"country":861,"countryCode":862,"cosmosGeoPoint":908,"geoPoint":912,"contacts":38},"Investigational Site Number 250007","Vénissieux","69200",{"type":52,"coordinates":909},[910,911],4.88593,45.69706,{"lat":911,"lon":910},{"facility":914,"status":38,"city":915,"state":38,"zip":916,"country":917,"countryCode":918,"cosmosGeoPoint":919,"geoPoint":923,"contacts":38},"Investigational Site Number 300005","Alexandroupoli","68100","Greece","GR",{"type":52,"coordinates":920},[921,922],25.87644,40.84995,{"lat":922,"lon":921},{"facility":925,"status":38,"city":926,"state":38,"zip":927,"country":917,"countryCode":918,"cosmosGeoPoint":928,"geoPoint":932,"contacts":38},"Investigational Site Number 300001","Athens","17562",{"type":52,"coordinates":929},[930,931],23.72784,37.98376,{"lat":931,"lon":930},{"facility":934,"status":38,"city":926,"state":38,"zip":38,"country":917,"countryCode":918,"cosmosGeoPoint":935,"geoPoint":937,"contacts":38},"Investigational Site Number 300002",{"type":52,"coordinates":936},[930,931],{"lat":931,"lon":930},{"facility":939,"status":38,"city":926,"state":38,"zip":38,"country":917,"countryCode":918,"cosmosGeoPoint":940,"geoPoint":942,"contacts":38},"Investigational Site Number 300003",{"type":52,"coordinates":941},[930,931],{"lat":931,"lon":930},{"facility":944,"status":38,"city":945,"state":38,"zip":946,"country":947,"countryCode":948,"cosmosGeoPoint":949,"geoPoint":953,"contacts":38},"Investigational Site Number 348004","Budapest","1042","Hungary","HU",{"type":52,"coordinates":950},[951,952],19.04045,47.49835,{"lat":952,"lon":951},{"facility":955,"status":38,"city":945,"state":38,"zip":956,"country":947,"countryCode":948,"cosmosGeoPoint":957,"geoPoint":959,"contacts":38},"Investigational Site Number 348002","1083",{"type":52,"coordinates":958},[951,952],{"lat":952,"lon":951},{"facility":961,"status":38,"city":945,"state":38,"zip":962,"country":947,"countryCode":948,"cosmosGeoPoint":963,"geoPoint":965,"contacts":38},"Investigational Site Number 348001","1106",{"type":52,"coordinates":964},[951,952],{"lat":952,"lon":951},{"facility":967,"status":38,"city":968,"state":38,"zip":969,"country":947,"countryCode":948,"cosmosGeoPoint":970,"geoPoint":974,"contacts":38},"Investigational Site Number 348003","Gyöngyös","3200",{"type":52,"coordinates":971},[972,973],19.928,47.78257,{"lat":973,"lon":972},{"facility":976,"status":38,"city":977,"state":38,"zip":978,"country":979,"countryCode":980,"cosmosGeoPoint":981,"geoPoint":985,"contacts":38},"Investigational Site Number 376001","Haifa","31096","Israel","IL",{"type":52,"coordinates":982},[983,984],34.99928,32.81303,{"lat":984,"lon":983},{"facility":987,"status":38,"city":977,"state":38,"zip":38,"country":979,"countryCode":980,"cosmosGeoPoint":988,"geoPoint":990,"contacts":38},"Investigational Site Number 376004",{"type":52,"coordinates":989},[983,984],{"lat":984,"lon":983},{"facility":992,"status":38,"city":977,"state":38,"zip":38,"country":979,"countryCode":980,"cosmosGeoPoint":993,"geoPoint":995,"contacts":38},"Investigational Site Number 376008",{"type":52,"coordinates":994},[983,984],{"lat":984,"lon":983},{"facility":997,"status":38,"city":998,"state":38,"zip":38,"country":979,"countryCode":980,"cosmosGeoPoint":999,"geoPoint":1003,"contacts":38},"Investigational Site Number 376009","Kfar Saba",{"type":52,"coordinates":1000},[1001,1002],34.90694,32.175,{"lat":1002,"lon":1001},{"facility":1005,"status":38,"city":1006,"state":38,"zip":38,"country":979,"countryCode":980,"cosmosGeoPoint":1007,"geoPoint":1011,"contacts":38},"Investigational Site Number 376002","Petah Tikva",{"type":52,"coordinates":1008},[1009,1010],34.88747,32.08707,{"lat":1010,"lon":1009},{"facility":1013,"status":38,"city":1014,"state":38,"zip":38,"country":979,"countryCode":980,"cosmosGeoPoint":1015,"geoPoint":1019,"contacts":38},"Investigational Site Number 376006","Tel Aviv",{"type":52,"coordinates":1016},[1017,1018],34.78057,32.08088,{"lat":1018,"lon":1017},{"facility":1021,"status":38,"city":1014,"state":38,"zip":38,"country":979,"countryCode":980,"cosmosGeoPoint":1022,"geoPoint":1024,"contacts":38},"Investigational Site Number 376007",{"type":52,"coordinates":1023},[1017,1018],{"lat":1018,"lon":1017},{"facility":1026,"status":38,"city":1027,"state":38,"zip":1028,"country":979,"countryCode":980,"cosmosGeoPoint":1029,"geoPoint":1033,"contacts":38},"Investigational Site Number 376003","Tel Litwinsky","52621",{"type":52,"coordinates":1030},[1031,1032],34.84588,32.05096,{"lat":1032,"lon":1031},{"facility":1035,"status":38,"city":1036,"state":38,"zip":1037,"country":1038,"countryCode":1039,"cosmosGeoPoint":1040,"geoPoint":1044,"contacts":38},"Investigational Site Number 380007","Bari","70124","Italy","IT",{"type":52,"coordinates":1041},[1042,1043],16.86982,41.12066,{"lat":1043,"lon":1042},{"facility":1046,"status":38,"city":1047,"state":38,"zip":38,"country":1038,"countryCode":1039,"cosmosGeoPoint":1048,"geoPoint":1052,"contacts":38},"Investigational Site Number 380009","Catanzaro",{"type":52,"coordinates":1049},[1050,1051],16.60086,38.88247,{"lat":1051,"lon":1050},{"facility":1054,"status":38,"city":1055,"state":38,"zip":1056,"country":1038,"countryCode":1039,"cosmosGeoPoint":1057,"geoPoint":1061,"contacts":38},"Investigational Site Number 380010","Chieti","66013",{"type":52,"coordinates":1058},[1059,1060],14.16494,42.34827,{"lat":1060,"lon":1059},{"facility":1063,"status":38,"city":1064,"state":38,"zip":1065,"country":1038,"countryCode":1039,"cosmosGeoPoint":1066,"geoPoint":1070,"contacts":38},"Investigational Site Number 380014","Milan","20132",{"type":52,"coordinates":1067},[1068,1069],12.59836,42.78235,{"lat":1069,"lon":1068},{"facility":1072,"status":38,"city":1073,"state":38,"zip":1074,"country":1038,"countryCode":1039,"cosmosGeoPoint":1075,"geoPoint":1079,"contacts":38},"Investigational Site Number 380002","Moncalieri","10024",{"type":52,"coordinates":1076},[1077,1078],7.68236,44.9994,{"lat":1078,"lon":1077},{"facility":1081,"status":38,"city":1082,"state":38,"zip":1083,"country":1038,"countryCode":1039,"cosmosGeoPoint":1084,"geoPoint":1088,"contacts":38},"Investigational Site Number 380011","Naples","80131",{"type":52,"coordinates":1085},[1086,1087],14.26811,40.85216,{"lat":1087,"lon":1086},{"facility":1090,"status":38,"city":1091,"state":38,"zip":38,"country":1038,"countryCode":1039,"cosmosGeoPoint":1092,"geoPoint":1096,"contacts":38},"Investigational Site Number 380008","Roma",{"type":52,"coordinates":1093},[1094,1095],11.10642,44.99364,{"lat":1095,"lon":1094},{"facility":1098,"status":38,"city":1091,"state":38,"zip":38,"country":1038,"countryCode":1039,"cosmosGeoPoint":1099,"geoPoint":1101,"contacts":38},"Investigational Site Number 380015",{"type":52,"coordinates":1100},[1094,1095],{"lat":1095,"lon":1094},{"facility":1103,"status":38,"city":1091,"state":38,"zip":38,"country":1038,"countryCode":1039,"cosmosGeoPoint":1104,"geoPoint":1106,"contacts":38},"Investigational Site Number 380016",{"type":52,"coordinates":1105},[1094,1095],{"lat":1095,"lon":1094},{"facility":1108,"status":38,"city":1109,"state":38,"zip":1110,"country":1038,"countryCode":1039,"cosmosGeoPoint":1111,"geoPoint":1115,"contacts":38},"Investigational Site Number 380013","Sesto San Giovanni","20099",{"type":52,"coordinates":1112},[1113,1114],9.22585,45.53329,{"lat":1114,"lon":1113},{"facility":1117,"status":38,"city":1118,"state":38,"zip":1119,"country":1038,"countryCode":1039,"cosmosGeoPoint":1120,"geoPoint":1124,"contacts":38},"Investigational Site Number 380005","Torino","10126",{"type":52,"coordinates":1121},[1122,1123],11.99138,44.88856,{"lat":1123,"lon":1122},{"facility":1126,"status":38,"city":1127,"state":38,"zip":1128,"country":1038,"countryCode":1039,"cosmosGeoPoint":1129,"geoPoint":1133,"contacts":38},"Investigational Site Number 380012","Verona","37126",{"type":52,"coordinates":1130},[1131,1132],10.9938,45.43854,{"lat":1132,"lon":1131},{"facility":1135,"status":38,"city":1136,"state":38,"zip":1137,"country":1138,"countryCode":1139,"cosmosGeoPoint":1140,"geoPoint":1144,"contacts":38},"Investigational Site Number 642007","Brasov","500097","Romania","RO",{"type":52,"coordinates":1141},[1142,1143],25.60613,45.64861,{"lat":1143,"lon":1142},{"facility":1146,"status":38,"city":1136,"state":38,"zip":1147,"country":1138,"countryCode":1139,"cosmosGeoPoint":1148,"geoPoint":1150,"contacts":38},"Investigational Site Number 642008","500326",{"type":52,"coordinates":1149},[1142,1143],{"lat":1143,"lon":1142},{"facility":1152,"status":38,"city":1153,"state":38,"zip":1154,"country":1138,"countryCode":1139,"cosmosGeoPoint":1155,"geoPoint":1159,"contacts":38},"Investigational Site Number 642001","Bucharest","022441",{"type":52,"coordinates":1156},[1157,1158],26.10626,44.43225,{"lat":1158,"lon":1157},{"facility":1161,"status":38,"city":1153,"state":38,"zip":1162,"country":1138,"countryCode":1139,"cosmosGeoPoint":1163,"geoPoint":1165,"contacts":38},"Investigational Site Number 642013","040172",{"type":52,"coordinates":1164},[1157,1158],{"lat":1158,"lon":1157},{"facility":1167,"status":38,"city":1153,"state":38,"zip":38,"country":1138,"countryCode":1139,"cosmosGeoPoint":1168,"geoPoint":1170,"contacts":38},"Investigational Site Number 642015",{"type":52,"coordinates":1169},[1157,1158],{"lat":1158,"lon":1157},{"facility":1172,"status":38,"city":1173,"state":38,"zip":1174,"country":1138,"countryCode":1139,"cosmosGeoPoint":1175,"geoPoint":1179,"contacts":38},"Investigational Site Number 642003","Cluj-Napoca","400006",{"type":52,"coordinates":1176},[1177,1178],23.6,46.76667,{"lat":1178,"lon":1177},{"facility":1181,"status":38,"city":1182,"state":38,"zip":1183,"country":1138,"countryCode":1139,"cosmosGeoPoint":1184,"geoPoint":1188,"contacts":38},"Investigational Site Number 642009","Constanța","900675",{"type":52,"coordinates":1185},[1186,1187],28.63432,44.18073,{"lat":1187,"lon":1186},{"facility":1190,"status":38,"city":1191,"state":38,"zip":1192,"country":1138,"countryCode":1139,"cosmosGeoPoint":1193,"geoPoint":1197,"contacts":38},"Investigational Site Number 642014","Iași","700547",{"type":52,"coordinates":1194},[1195,1196],27.6,47.16667,{"lat":1196,"lon":1195},{"facility":1199,"status":38,"city":1200,"state":38,"zip":38,"country":1138,"countryCode":1139,"cosmosGeoPoint":1201,"geoPoint":1205,"contacts":38},"Investigational Site Number 642005","Oradea",{"type":52,"coordinates":1202},[1203,1204],21.91833,47.0458,{"lat":1204,"lon":1203},{"facility":1207,"status":38,"city":1200,"state":38,"zip":38,"country":1138,"countryCode":1139,"cosmosGeoPoint":1208,"geoPoint":1210,"contacts":38},"Investigational Site Number 642012",{"type":52,"coordinates":1209},[1203,1204],{"lat":1204,"lon":1203},{"facility":1212,"status":38,"city":1213,"state":38,"zip":1214,"country":1138,"countryCode":1139,"cosmosGeoPoint":1215,"geoPoint":1219,"contacts":38},"Investigational Site Number 642010","Târgu Mureş","540015",{"type":52,"coordinates":1216},[1217,1218],24.55747,46.54245,{"lat":1218,"lon":1217},{"facility":1221,"status":38,"city":1213,"state":38,"zip":1222,"country":1138,"countryCode":1139,"cosmosGeoPoint":1223,"geoPoint":1225,"contacts":38},"Investigational Site Number 642004","540142",{"type":52,"coordinates":1224},[1217,1218],{"lat":1218,"lon":1217},{"facility":1227,"status":38,"city":1213,"state":38,"zip":38,"country":1138,"countryCode":1139,"cosmosGeoPoint":1228,"geoPoint":1230,"contacts":38},"Investigational Site Number 642006",{"type":52,"coordinates":1229},[1217,1218],{"lat":1218,"lon":1217},{"facility":1232,"status":38,"city":1233,"state":38,"zip":792,"country":1234,"countryCode":1235,"cosmosGeoPoint":1236,"geoPoint":1240,"contacts":38},"Investigational Site Number 688001","Belgrade","Serbia","RS",{"type":52,"coordinates":1237},[1238,1239],20.46513,44.80401,{"lat":1239,"lon":1238},{"facility":1242,"status":38,"city":1243,"state":38,"zip":38,"country":1234,"countryCode":1235,"cosmosGeoPoint":1244,"geoPoint":1248,"contacts":38},"Investigational Site Number 688002","Niš",{"type":52,"coordinates":1245},[1246,1247],21.90333,43.32472,{"lat":1247,"lon":1246},{"facility":1250,"status":38,"city":1243,"state":38,"zip":38,"country":1234,"countryCode":1235,"cosmosGeoPoint":1251,"geoPoint":1253,"contacts":38},"Investigational Site Number 688003",{"type":52,"coordinates":1252},[1246,1247],{"lat":1247,"lon":1246},{"facility":1255,"status":38,"city":1256,"state":38,"zip":1257,"country":1258,"countryCode":1259,"cosmosGeoPoint":1260,"geoPoint":1264,"contacts":38},"Investigational Site Number 703006","Košice","04013","Slovakia","SK",{"type":52,"coordinates":1261},[1262,1263],21.25802,48.71441,{"lat":1263,"lon":1262},{"facility":1266,"status":38,"city":1267,"state":38,"zip":1268,"country":1258,"countryCode":1259,"cosmosGeoPoint":1269,"geoPoint":1273,"contacts":38},"Investigational Site Number 703002","Ľubochňa","03491",{"type":52,"coordinates":1270},[1271,1272],19.16891,49.12011,{"lat":1272,"lon":1271},{"facility":1275,"status":38,"city":1276,"state":38,"zip":1277,"country":1258,"countryCode":1259,"cosmosGeoPoint":1278,"geoPoint":1282,"contacts":38},"Investigational Site Number 703001","Moldava nad Bodvou","04525",{"type":52,"coordinates":1279},[1280,1281],20.99957,48.61428,{"lat":1281,"lon":1280},{"facility":1284,"status":38,"city":1285,"state":38,"zip":1286,"country":1258,"countryCode":1259,"cosmosGeoPoint":1287,"geoPoint":1291,"contacts":38},"Investigational Site Number 703003","Sabinov","08301",{"type":52,"coordinates":1288},[1289,1290],21.0988,49.10309,{"lat":1290,"lon":1289},{"facility":1293,"status":38,"city":1294,"state":38,"zip":1295,"country":1258,"countryCode":1259,"cosmosGeoPoint":1296,"geoPoint":1300,"contacts":38},"Investigational Site Number 703005","Trebišov","07501",{"type":52,"coordinates":1297},[1298,1299],21.71954,48.62858,{"lat":1299,"lon":1298},{"facility":1302,"status":38,"city":1303,"state":38,"zip":1304,"country":1305,"countryCode":1306,"cosmosGeoPoint":1307,"geoPoint":1311,"contacts":38},"Investigational Site Number 752102","Lund","22241","Sweden","SE",{"type":52,"coordinates":1308},[1309,1310],13.19321,55.70584,{"lat":1310,"lon":1309},{"facility":1313,"status":38,"city":1314,"state":38,"zip":1315,"country":1305,"countryCode":1306,"cosmosGeoPoint":1316,"geoPoint":1320,"contacts":38},"Investigational Site Number 752101","Skövde","54150",{"type":52,"coordinates":1317},[1318,1319],13.84506,58.39118,{"lat":1319,"lon":1318},{"facility":1322,"status":38,"city":1323,"state":38,"zip":1324,"country":1325,"countryCode":1326,"cosmosGeoPoint":1327,"geoPoint":1331,"contacts":38},"Investigational Site Number 756003","Olten","4600","Switzerland","CH",{"type":52,"coordinates":1328},[1329,1330],7.90329,47.34999,{"lat":1330,"lon":1329},{"facility":1333,"status":38,"city":1334,"state":38,"zip":1335,"country":1325,"countryCode":1326,"cosmosGeoPoint":1336,"geoPoint":1340,"contacts":38},"Investigational Site Number 756001","Sankt Gallen","9016",{"type":52,"coordinates":1337},[1338,1339],9.37477,47.42391,{"lat":1339,"lon":1338},{"facility":1342,"status":38,"city":1343,"state":38,"zip":1344,"country":1345,"countryCode":1346,"cosmosGeoPoint":1347,"geoPoint":1351,"contacts":38},"Investigational Site Number 826001","Chertsey","KT160PZ","United Kingdom","UK",{"type":52,"coordinates":1348},[1349,1350],-0.50782,51.38812,{"lat":1350,"lon":1349},{"facility":1353,"status":38,"city":1354,"state":38,"zip":1355,"country":1345,"countryCode":1346,"cosmosGeoPoint":1356,"geoPoint":1360,"contacts":38},"Investigational Site Number 826005","Gillingham","ME75NY",{"type":52,"coordinates":1357},[1358,1359],0.54863,51.38914,{"lat":1359,"lon":1358},{"facility":1362,"status":38,"city":1363,"state":38,"zip":1364,"country":1345,"countryCode":1346,"cosmosGeoPoint":1365,"geoPoint":1369,"contacts":38},"Investigational Site Number 826008","Lincoln","LN25QY",{"type":52,"coordinates":1366},[1367,1368],-0.53792,53.22683,{"lat":1368,"lon":1367},{"facility":1371,"status":38,"city":1372,"state":38,"zip":1373,"country":1345,"countryCode":1346,"cosmosGeoPoint":1374,"geoPoint":1378,"contacts":38},"Investigational Site Number 826002","London","SW109NH",{"type":52,"coordinates":1375},[1376,1377],-0.12574,51.50853,{"lat":1377,"lon":1376},{"facility":1380,"status":38,"city":1381,"state":38,"zip":1382,"country":1345,"countryCode":1346,"cosmosGeoPoint":1383,"geoPoint":1387,"contacts":38},"Investigational Site Number 826009","Manchester","M415SL",{"type":52,"coordinates":1384},[1385,1386],-2.23743,53.48095,{"lat":1386,"lon":1385},{"facility":1389,"status":38,"city":1390,"state":38,"zip":1391,"country":1345,"countryCode":1346,"cosmosGeoPoint":1392,"geoPoint":1396,"contacts":38},"Investigational Site Number 826006","Margate","CT94ANA",{"type":52,"coordinates":1393},[1394,1395],1.38617,51.38132,{"lat":1395,"lon":1394},{"facility":1398,"status":38,"city":1399,"state":38,"zip":1400,"country":1345,"countryCode":1346,"cosmosGeoPoint":1401,"geoPoint":1405,"contacts":38},"Investigational Site Number 826004","Swansea","SA66NL",{"type":52,"coordinates":1402},[1403,1404],-3.94323,51.62079,{"lat":1404,"lon":1403},{"type":1407,"investigatorFullName":38,"investigatorTitle":38,"investigatorAffiliation":38,"oldNameTitle":38,"oldOrganization":38},"SPONSOR","100265699","phase-4-efficacy-and-safety-of-toujeo-versus-tresiba-in-insulin-naive-patients-with-type-2-diabetes-mellitus-inadequately-controlled-with-oral-antihyperglycemic-drugs--glp-1-receptor-agonist-100265699",true,"NCT02738151","Efficacy and Safety of Toujeo® Versus Tresiba® in Insulin-Naive Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Oral Antihyperglycemic Drug(s) ± GLP-1 Receptor Agonist","A 24-week, Multicenter, Randomized, Open-Label, Parallel-group StudyComparing the Efficacy and Safety of Toujeo® and Tresiba® in Insulin-NaivePatients With Type 2 Diabetes Mellitus Not Adequately Controlled With OralAntihyperglycemic Drug(s) ± GLP-1 Receptor Agonist","BRIGHT","Inclusion criteria :\n\n* Adult participants with type 2 diabetes mellitus (T2DM) inadequately controlled with OADs therapy with\u002Fwithout GLP-1 receptor agonist at stable dose for at least 3 months.\n* Signed written informed consent.\n\nExclusion criteria:\n\n* Age \\\u003C18 years.\n* HbA1c \\\u003C7.5% or \\>10.5% (at screening visit). Body mass index (BMI) \\\u003C25 kg\u002Fm\\^2 or \\>40 kg\u002Fm\\^2.\n* History of T2DM for less than 1 year before screening.\n* Less than 6 months before screening on OADs treatment and GLP-1 receptor agonist (if taken).\n* Current or previous insulin use except for a maximum of 8 consecutive days or totally 15 days (eg, acute illness, surgery) during the last year prior to screening.\n* Initiation of new glucose-lowering medications and\u002For weight loss drug in the last 3 months before screening visit.\n* Participant receiving only noninsulin antihyperglycemic drugs not approved for combination with insulin according to local labelling\u002Flocal treatment guideline.\n* History of hypoglycemia unawareness or repeated episodes of severe hypoglycemia or metabolic acidosis, including hospitalization for diabetic ketoacidosis during the last 12 months prior to screening.\n* Unstable proliferative diabetic retinopathy or any other rapidly progressive diabetic retinopathy or macular edema likely to require treatment (eg, laser, surgical treatment, or injectable drugs) during the study period.\n* End stage renal disease.\n* Any acute or chronic condition that in the opinion of Investigator would affect the safety of participant, compliance, or study results.\n* Any contraindication to use of Toujeo® or Tresiba® as defined in the national product label, hypersensitivity to Toujeo® or Tresiba® active ingredients or one of the excipients.\n* Pregnant or breast-feeding women.\n\nThe above information is not intended to contain all considerations relevant to a participant's potential participation in a clinical trial.",false,"ALL","18 Years",{"count":1420,"type":1421},929,"ACTUAL","INTERVENTIONAL",[1424],"PHASE4","Primary Objective:\n\nTo demonstrate the noninferiority in the efficacy of Toujeo® to Tresiba® in glycated hemoglobin (HbA1c) change from Baseline to Week 24.\n\nSecondary Objectives:\n\nChange From Baseline in HbA1c to Week 12\n\nTo assess the effects of the insulin Toujeo® in comparison with insulin Tresiba® at week 12 and week 24 on:\n\n* Change in Fasting plasma glucose (FPG);\n* Change in Fasting self-monitored plasma glucose (SMPG) and 4-point SMPG and 8-point SMPG profile;\n* Percentage of participants reaching HbA1c targets \\\u003C7% or ≤6.5%;\n* Percentage of participants reaching HbA1c targets \\\u003C7% or ≤6.5% without severe and\u002For confirmed hypoglycemia\n* Frequency of occurrence and diurnal distribution of hypoglycemia by American Diabetes Association (ADA) category of hypoglycemia.\n\nTo assess the safety in each treatment group.\n\nTo assess the treatment effects in each treatment group on Patient Reported Outcomes (PRO).\n\nPercentage of participants requiring rescue therapy.",[1427],"Diabetes Mellitus, Type 2","COMPLETED","2018-08-14",{"date":1431,"type":1421},"2018-09-14",{"date":1433,"type":38},"2016-05-19",{"date":1435,"type":1421},"2017-08-15",{"name":5,"class":6},158]