[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100402519":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":32,"locations":43,"responsibleParty":65,"collaborators":69,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":37,"enrollmentInfo":82,"targetDuration":37,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":37,"overallStatus":91,"whyStopped":37,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","PLACEBO_COMPARATOR","Participants in this arm will receive a nasal spray with placebo",[13],"Drug: Iota-Carrageenan",{"label":15,"type":16,"description":17,"interventionNames":18},"Experimental","EXPERIMENTAL","Participants in this arm will receive a nasal spray with Iota-Carrageenan",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Iota-Carrageenan","Participants will received a nasal spray with Iota-Carrageenan or placebo 4 times a day during 21 days",[9,15],[26],"Placebo",[28],{"name":29,"affiliation":30,"role":31},"Juan Figueroa, MD","Instituto Milstein-CONICET","STUDY_DIRECTOR",[33,39],{"name":34,"role":35,"phone":36,"phoneExt":37,"email":38},"Mónica Lombardo, MD","CONTACT","005491141763599",null,"mlombardo@nobeltri.com",{"name":40,"role":35,"phone":41,"phoneExt":37,"email":42},"Ricardo Valentini, MD","005491162036790","deptomedicina2@gmail.com",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"centro de educación médica e investigaciones clinicas (CEMIC)","RECRUITING","Buenos Aires","Buenos Aires F.D.","1425","Argentina","AR",{"type":53,"coordinates":54},"Point",[55,56],-58.37723,-34.61315,{"lat":56,"lon":55},[59,61],{"name":34,"role":35,"phone":60,"phoneExt":37,"email":38},"541152990600",{"name":62,"role":35,"phone":63,"phoneExt":37,"email":64},"Ricardo c Valentini","+541152990600","rvalentini@cemic.edu.ar",{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":37,"oldOrganization":37},"SPONSOR_INVESTIGATOR","Ariel Dogliotti","PHYSICIAN",[70],{"name":5,"class":6},"100402519","phase-4-efficacy-of-a-nasal-spray-containing-iota-carrageenan-in-the-prophylaxis-of-covid-19-disease-in-health-personnel-dedicated-to-patients-care-with-covid-19-disease-100402519",false,"NCT04521322","Efficacy of a Nasal Spray Containing Iota-Carrageenan in the Prophylaxis of COVID-19 Disease in Health Personnel Dedicated to Patients Care With COVID-19 Disease","Efficacy of a Nasal Spray Containing Iota-Carrageenan in the Prophylaxis of COVID-19 Disease in Health Personnel Dedicated to Patients Care With COVID-19. Multicenter, Randomized, Double-blind, Placebo-controlled Trial (CARR-COV-02)","CARR-COV-02","Inclusion Criteria:\n\n* physician, nurses, and physical therapist who usually attend hospitalized COVID19 patients.\n* No more than 48 hours since he\u002Fshe assisted a COVID-19 patient\n* Able to understand and give written informed consent\n\nExclusion Criteria:\n\n* Participation in any other clinical trial of an experimental treatment for COVID-19\n* Not having a cell phone with WhatsApp for remote monitoring\n* Hypersensitivity or known allergy to any component of the product\n* Pregnancy or lactation",true,"ALL","18 Years",{"count":83,"type":84},400,"ESTIMATED","INTERVENTIONAL",[87],"PHASE4","Coronaviruses are enveloped viruses with an RNA genome. Carrageenans are sulfate polysaccharides synthesized by red algae. Studies conducted in adults and children with the common cold showed the effectiveness of the use of Carrageenan in nasal spray.\n\nFor decades, the antiviral action of Carrageenans has been described in numerous studies with different viruses that infect humans: herpes viruses types 1 and 2, human immunodeficiency virus, human papillomavirus, H1N1 influenza virus, dengue virus, rhinovirus, hepatitis A virus, and enteroviruses. Studies on the dynamics of COVID-19 disease show an intense and rapid pharyngeal multiplication in the first 3-5 days of the onset of symptoms, prior to the onset of pulmonary disease.\n\nFinally, this molecule has shown a viricidal effect against SARS-Cov2 in vitro. All this underscores the potential value of a therapy that inhibits the virus in the rhinopharynx.",[90],"Covid19","UNKNOWN","2020-08-19",{"date":94,"type":95},"2020-08-21","ACTUAL",{"date":97,"type":95},"2020-07-24",{"date":99,"type":84},"2020-11-30",{"name":67,"class":6},1]