[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100214707":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":29,"locations":30,"responsibleParty":228,"collaborators":29,"id":230,"slug":231,"hasResults":232,"nctId":233,"briefTitle":234,"officialTitle":235,"acronym":29,"eligibilityCriteria":236,"healthyVolunteers":237,"sex":238,"minAge":239,"maxAge":240,"enrollmentInfo":241,"targetDuration":29,"studyType":244,"phases":245,"briefSummary":247,"conditions":248,"keywords":29,"overallStatus":250,"whyStopped":29,"lastUpdateSubmitDate":251,"lastUpdatePostDateStruct":252,"startDateStruct":254,"completionDateStruct":256,"leadSponsor":258,"locationsCount":259},{"fullName":5,"class":6},"Materia Medica Holding","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Anaferon for Children","EXPERIMENTAL","On day 1, five tablets are taken in the first 2 hours (one tablet every 30 min), followed by three more tablets regularly spaced during the rest of the day. From day 2 through 5, one tablet is administered three times daily.",[13],"Drug: Anaferon for Children",{"label":15,"type":16,"description":11,"interventionNames":17},"Placebo","PLACEBO_COMPARATOR",[13],[19],{"type":20,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"DRUG","Anaferon for children: For oral use.",[9,15],[24],"Anaferon for Children in tablets",[26],{"name":27,"affiliation":5,"role":28},"Elena Andrianova, Professor","STUDY_DIRECTOR",null,[31,43,49,55,66,72,77,82,88,94,100,109,118,127,136,145,151,157,163,169,175,184,193,198,203,208,219],{"facility":32,"status":29,"city":33,"state":29,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":29},"City Child Health Clinical Polyclinic №13","Minsk","220024","Belarus","BY",{"type":38,"coordinates":39},"Point",[40,41],27.56653,53.90019,{"lat":41,"lon":40},{"facility":44,"status":29,"city":33,"state":29,"zip":45,"country":35,"countryCode":36,"cosmosGeoPoint":46,"geoPoint":48,"contacts":29},"Municipal Health Care Institution \"City Child Health Clinical Polyclinic №10\"","220118",{"type":38,"coordinates":47},[40,41],{"lat":41,"lon":40},{"facility":50,"status":29,"city":33,"state":29,"zip":51,"country":35,"countryCode":36,"cosmosGeoPoint":52,"geoPoint":54,"contacts":29},"City Child Health Clinical Polyclinic №17","220131",{"type":38,"coordinates":53},[40,41],{"lat":41,"lon":40},{"facility":56,"status":29,"city":57,"state":29,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":65,"contacts":29},"Clinic of State Budgetary Institution \"Research Institute of nutrition\" of the Russian Academy of Medical Sciences","Moscow","109240","Russia","RU",{"type":38,"coordinates":62},[63,64],37.61781,55.75204,{"lat":64,"lon":63},{"facility":67,"status":29,"city":57,"state":29,"zip":68,"country":59,"countryCode":60,"cosmosGeoPoint":69,"geoPoint":71,"contacts":29},"Russian National Research Medical University named after N.I. Pirogov","117997",{"type":38,"coordinates":70},[63,64],{"lat":64,"lon":63},{"facility":73,"status":29,"city":57,"state":29,"zip":68,"country":59,"countryCode":60,"cosmosGeoPoint":74,"geoPoint":76,"contacts":29},"Russian National Research Medical University",{"type":38,"coordinates":75},[63,64],{"lat":64,"lon":63},{"facility":78,"status":29,"city":57,"state":29,"zip":68,"country":59,"countryCode":60,"cosmosGeoPoint":79,"geoPoint":81,"contacts":29},"Russian National Research Pirogov Medical University",{"type":38,"coordinates":80},[63,64],{"lat":64,"lon":63},{"facility":83,"status":29,"city":57,"state":29,"zip":84,"country":59,"countryCode":60,"cosmosGeoPoint":85,"geoPoint":87,"contacts":29},"State Educational Institution of Higher Professional Education \"Moscow State Medical Academy named after I.M. Sechenov\"","119991",{"type":38,"coordinates":86},[63,64],{"lat":64,"lon":63},{"facility":89,"status":29,"city":57,"state":29,"zip":90,"country":59,"countryCode":60,"cosmosGeoPoint":91,"geoPoint":93,"contacts":29},"State Budgetary Institution of Health, \"Children's City Hospital № 9 named after G.N. Speranskii\"","123317",{"type":38,"coordinates":92},[63,64],{"lat":64,"lon":63},{"facility":95,"status":29,"city":57,"state":29,"zip":96,"country":59,"countryCode":60,"cosmosGeoPoint":97,"geoPoint":99,"contacts":29},"State Budgetary Educational Institution of Additional Professional Education \"Russian Russian Medical Academy of Postgraduate Education\" of Ministry of Health of Russian Federation","123995",{"type":38,"coordinates":98},[63,64],{"lat":64,"lon":63},{"facility":101,"status":29,"city":102,"state":29,"zip":103,"country":59,"countryCode":60,"cosmosGeoPoint":104,"geoPoint":108,"contacts":29},"State Budgetary Educational Institution of Higher Professional Education \" Nizhny Novgorod State Medical Academy\" of Ministry of Health of Russian Federation","Nizhny Novgorod","603005",{"type":38,"coordinates":105},[106,107],44.00205,56.32867,{"lat":107,"lon":106},{"facility":110,"status":29,"city":111,"state":29,"zip":112,"country":59,"countryCode":60,"cosmosGeoPoint":113,"geoPoint":117,"contacts":29},"State Budgetary Educational Institution of Higher Professional Education ''Novosibirsk State Medical University'' of Ministry of Health of Russian Federation","Novosibirsk","630091",{"type":38,"coordinates":114},[115,116],82.93175,55.02259,{"lat":116,"lon":115},{"facility":119,"status":29,"city":120,"state":29,"zip":121,"country":59,"countryCode":60,"cosmosGeoPoint":122,"geoPoint":126,"contacts":29},"Municipal Health Care Institution \"City Child Health Clinical Polyclinic №5\"","Perm","614066",{"type":38,"coordinates":123},[124,125],56.25017,58.01046,{"lat":125,"lon":124},{"facility":128,"status":29,"city":129,"state":29,"zip":130,"country":59,"countryCode":60,"cosmosGeoPoint":131,"geoPoint":135,"contacts":29},"State Budgetary Educational Institution of Higher Professional Education \"Rostov State Medical University\"","Rostov-on-Don","344022",{"type":38,"coordinates":132},[133,134],39.70769,47.21997,{"lat":134,"lon":133},{"facility":137,"status":29,"city":138,"state":29,"zip":139,"country":59,"countryCode":60,"cosmosGeoPoint":140,"geoPoint":144,"contacts":29},"St. Petersburg State Budgetary Health Care Institution \"Сity Polyclinic №44\"","Saint Petersburg","192212",{"type":38,"coordinates":141},[142,143],30.31413,59.93863,{"lat":143,"lon":142},{"facility":146,"status":29,"city":138,"state":29,"zip":147,"country":59,"countryCode":60,"cosmosGeoPoint":148,"geoPoint":150,"contacts":29},"St. Petersburg State health institution \" City Child Health Polyclinic № 45\"","193312",{"type":38,"coordinates":149},[142,143],{"lat":143,"lon":142},{"facility":152,"status":29,"city":138,"state":29,"zip":153,"country":59,"countryCode":60,"cosmosGeoPoint":154,"geoPoint":156,"contacts":29},"State Budgetary Educational Institution of Higher Professional Education \"St. Petersburg State Pediatric Medical Academy\" of Ministry of Health of Russian Federation","194100",{"type":38,"coordinates":155},[142,143],{"lat":143,"lon":142},{"facility":158,"status":29,"city":138,"state":29,"zip":159,"country":59,"countryCode":60,"cosmosGeoPoint":160,"geoPoint":162,"contacts":29},"Limited Liability Company \"Alliance Biomedical-Russian group\"","194356",{"type":38,"coordinates":161},[142,143],{"lat":143,"lon":142},{"facility":164,"status":29,"city":138,"state":29,"zip":165,"country":59,"countryCode":60,"cosmosGeoPoint":166,"geoPoint":168,"contacts":29},"Co.Ltd \"Clinic Allergomed\"","196084",{"type":38,"coordinates":167},[142,143],{"lat":143,"lon":142},{"facility":170,"status":29,"city":138,"state":29,"zip":171,"country":59,"countryCode":60,"cosmosGeoPoint":172,"geoPoint":174,"contacts":29},"State Health Care Institution \"Child Health City Hospital №22\"","196650",{"type":38,"coordinates":173},[142,143],{"lat":143,"lon":142},{"facility":176,"status":29,"city":177,"state":29,"zip":178,"country":59,"countryCode":60,"cosmosGeoPoint":179,"geoPoint":183,"contacts":29},"Bashkir State Medical University of Ministry of Health of Russian Federation","Ufa","450000",{"type":38,"coordinates":180},[181,182],55.96779,54.74306,{"lat":182,"lon":181},{"facility":185,"status":29,"city":186,"state":29,"zip":187,"country":59,"countryCode":60,"cosmosGeoPoint":188,"geoPoint":192,"contacts":29},"State Budgetary Educational Institution of Higher Professional Education \" Yaroslavl State Medical Academy\" of Ministry of Health of Russian Federation","Yaroslavl","150000",{"type":38,"coordinates":189},[190,191],39.87368,57.62987,{"lat":191,"lon":190},{"facility":194,"status":29,"city":186,"state":29,"zip":187,"country":59,"countryCode":60,"cosmosGeoPoint":195,"geoPoint":197,"contacts":29},"State Budgetary Educational Institution of Higher Professional Education \"Yaroslavl State Medical Academy\"",{"type":38,"coordinates":196},[190,191],{"lat":191,"lon":190},{"facility":199,"status":29,"city":186,"state":29,"zip":187,"country":59,"countryCode":60,"cosmosGeoPoint":200,"geoPoint":202,"contacts":29},"State Budgetary Educational Institution of Higher Professional Education \"Yaroslavl State Medical Academy",{"type":38,"coordinates":201},[190,191],{"lat":191,"lon":190},{"facility":204,"status":29,"city":186,"state":29,"zip":187,"country":59,"countryCode":60,"cosmosGeoPoint":205,"geoPoint":207,"contacts":29},"Yaroslavl State Medical Academy",{"type":38,"coordinates":206},[190,191],{"lat":191,"lon":190},{"facility":209,"status":29,"city":210,"state":29,"zip":211,"country":212,"countryCode":213,"cosmosGeoPoint":214,"geoPoint":218,"contacts":29},"Vinnytsya M.I. Pyrogov National Medical University","Vinnytsia","21018","Ukraine","UA",{"type":38,"coordinates":215},[216,217],28.46871,49.2322,{"lat":217,"lon":216},{"facility":220,"status":29,"city":221,"state":29,"zip":222,"country":212,"countryCode":213,"cosmosGeoPoint":223,"geoPoint":227,"contacts":29},"Public institution \"Zaporizhzhya city multidisciplinary children's hospital №5\"","Zaporozh’ye","69076",{"type":38,"coordinates":224},[225,226],38.71939,48.27361,{"lat":226,"lon":225},{"type":229,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR","100214707","phase-4-efficacy-of-anaferon-for-children-in-the-treatment-of-influenza-and-acute-respiratory-viral-infections-in-children-100214707",true,"NCT02072174","Efficacy of Anaferon for Children in the Treatment of Influenza and Acute Respiratory Viral Infections in Children","International Multicenter Double-blind Placebo-controlled Randomized Parallel Group Clinical Trial of Efficacy of Anaferon for Children in the Treatment of Influenza and Acute Respiratory Viral Infections in Children","Inclusion Criteria:\n\n1. Patients of both sexes aged 3-12 years inclusively.\n2. Diagnosis of influenza\u002FARVI according to physician's examination: body temperature ≥ 38.0°C at the time of examination + symptom score ≥ 4 (at least 1 systemic symptom ≥2 and 1 nasal\u002Fthroat\u002Fchest symptom ≥2 or several symptoms ≥ 1 score).\n3. The first 24 hours from the beginning of manifestations of influenza\u002FARVI.\n4. The possibility to start therapy within 24 hours from the first symptoms of ARVI.\n5. Availability of a patient information sheet (Informed Consent form) for parents\u002Fadoptive parents for participation in the study signed by one of the parents\u002Fadoptive parents.\n\nExclusion Criteria:\n\n1. Suspected pneumonia, bacterial infection or severe disease requiring antibacterial products (including sulfanilamides) starting from the first day of the disease.\n2. Clinical symptoms of severe influenza\u002FARVI requiring hospitalization.\n3. Suspected initial manifestations of the diseases having the symptoms similar to the ones of influenza\u002FARVI (other infectious diseases, influenza-like syndrome at debut of systemic connective tissue diseases, oncohematological and other diseases).\n4. Medical history of primary and secondary immunodeficiencies: а) lymphoid system immunodeficiencies (Т-cell and\u002For B-cell, immunodeficiencies with predominant antibody deficiency); b) phagocytic deficiencies; c) complement factor deficiency; d) combined immunodeficiencies including AIDS secondary to HIV-infection; toxic, autoimmune, infectious, radiation panleukopenic syndrome; systemic lymphocytopenic syndrome; polyclonal lymphocytic activation syndrome; postsplenectomic syndrome; congenital asplenia; immune complex pathological syndrome associated with infectious, autoimmune and allergic diseases.\n5. Medical history of sarcoidosis.\n6. Oncology.\n7. Exacerbation or decompensation of chronic diseases affecting ability to participate in the clinical study.\n8. Medical history of polyvalent allergy.\n9. Allergy\u002Fintolerance to any of the components of medications used in the treatment.\n10. Malabsorption syndrome, including congenital or acquired lactase or other disaccharidase deficiency, galactosemia.\n11. Intake of medicines listed in the section \"Prohibited concomitant therapy\" within 1 month prior to the inclusion in the study.\n12. Drug addiction, alcohol consumption at more than 2 alcohol units per day by the subject's parents\u002Fadoptive parents.\n13. Mental diseases of the subject, parents\u002Fadoptive parents.\n14. Subjects whose parents\u002Fadoptive parents, according to the investigator's point of view, will not follow the observation requirements during the study or study product dosing regimen.\n15. Participation in other clinical studies within 3 months prior to the inclusion in the study.\n16. Parent\u002Fadoptive parent of the subject is related to the investigator team of medical facility directly involved in the study or is a close relative of the investigator. Close relatives include spouse, parents, children or brothers (sisters) regardless of whether they are biological or adoptive ones.\n17. Parent\u002Fadoptive parent of the subject is working in OOO \"NPF \"Materia Medica Holding\", i.e. is the company official, temporary contract worker or an appointed official responsible for the study or their close relatives.",false,"ALL","3 Years","12 Years",{"count":242,"type":243},569,"ACTUAL","INTERVENTIONAL",[246],"PHASE4","The purpose of this study is:\n\n• To obtain additional data on therapeutic efficacy of Anaferon for children in the treatment of influenza and acute respiratory viral infections in children",[249],"Influenza and Acute Respiratory Viral Infections","COMPLETED","2019-07-11",{"date":253,"type":243},"2019-07-12",{"date":255,"type":243},"2014-10-08",{"date":257,"type":243},"2018-04-16",{"name":5,"class":6},27]