[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100505413":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":36,"centralContacts":41,"locations":48,"responsibleParty":67,"collaborators":35,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":35,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":35,"studyType":82,"phases":83,"briefSummary":73,"conditions":85,"keywords":87,"overallStatus":89,"whyStopped":35,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Xijing Hospital","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"control group","PLACEBO_COMPARATOR","The patients were divided into 3 groups based on different dosages of Dezocine injection, with 35 patients in each group: Group 1: Dezocine low-dose group, Group 2: Dezocine high-dose group; Group 3: Blank control group (normal saline).",[13],"Device: Fractional CO2 laser",{"label":15,"type":16,"description":11,"interventionNames":17},"Dezocine low dose group","EXPERIMENTAL",[13,18],"Drug: Dezocine",{"label":20,"type":16,"description":11,"interventionNames":21},"Dezocine high dose group",[13,18],[23,30],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DEVICE","Fractional CO2 laser","All patients were given oral administration of 0.5mg paronosetron hydrochloride and lidocaine cream 1 hour before surgery. After cleaning and disinfection, fractional CO2 laser treatment was given. Among them, the fractional CO2 laser laser (American Medical Laser company) selected relatively constant energy parameters in the treatment",[20,15,9],[29],"paronosetron hydrochloride and lidocaine cream",{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"DRUG","Dezocine","Desocine injection was injected intravenously half an hour before surgery (10ml normal saline was added for more than 30 seconds)",[20,15],null,[37],{"name":38,"affiliation":39,"role":40},"Gang Wang, Prof","Dermatology Derpartment of Xijing Hospital","PRINCIPAL_INVESTIGATOR",[42],{"name":43,"role":44,"phone":45,"phoneExt":46,"email":47},"Chen Yu, MD","CONTACT","13571991903","86","ycyc_2005@163.com",[49],{"facility":39,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Xi'an","Shaanxi","710032","China","CN",{"type":57,"coordinates":58},"Point",[59,60],108.92861,34.25833,{"lat":60,"lon":59},[63],{"name":64,"role":44,"phone":65,"phoneExt":35,"email":66},"Gang Wang, prof","+8684775401","xjwgang@fmmu.edu.cn",{"type":68,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR","100505413","phase-4-the-efficacy-and-safety-of-dezocine-pretreatment-for-pain-relief-in-acne-scar-treatment-of-fractional-co2-laser-100505413",false,"NCT05861063","The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser","The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar","Inclusion Criteria:\n\n1. Age: 18-60 years old, regardless of gender;\n2. Clinical diagnosis of atrophic acne scars;\n3. Planning to undergo ultra-pulsed CO2 lattice laser therapy;\n4. The patient agrees to participate in this experiment and signs an informed consent form\n\nExclusion Criteria:\n\n1. Those who take sedative drugs for a long time;\n2. Patients with sleep apnea syndrome, previous history of hypertension, and blood pressure greater than 160\u002F100mmHg\n3. People with severe heart and lung diseases, liver and kidney diseases, psychosis, pregnancy, and communication disorders;\n4. Persons who are known to be allergic to the main drug or any of the excipients in Dezocine injection;\n5. Increased intracranial pressure or head injury;\n6. Acute and chronic alcoholism;\n7. People with hypotension, hypothyroidism, acute episodes of asthma, and epilepsy\n\n   \\-","ALL","18 Years","60 Years",{"count":80,"type":81},105,"ESTIMATED","INTERVENTIONAL",[84],"PHASE4",[86],"Acne Atrophica",[88],"Acne Scar, Dezocine, Pain Relief, Fractional CO2 Laser","UNKNOWN","2023-05-15",{"date":92,"type":93},"2023-05-16","ACTUAL",{"date":95,"type":93},"2023-02-11",{"date":97,"type":81},"2024-12-31",{"name":5,"class":6},1]