[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100306278":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":22,"centralContacts":10,"locations":27,"responsibleParty":41,"collaborators":44,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":71,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"antiCCP positive",null,"Patients with a positive result in the anti-CCP quick test and positive in antiCCP ELISA will be examined by Rheumatologist for detection of RA symptoms and followed-up for 3 years or until RA diagnosis\n\nno intervention is given",[13],"Other: no intervention is given",{"label":15,"type":10,"description":16,"interventionNames":17},"antiCCP negative","Patient with negative result in antiCCP quick test or negative antiCCP ELISA will be followed-up after one year (and 3 years for ELISA negative patients) with a short questionnaire if musculoskeletal symptoms are still present or if RA was diagnosed",[13],[19],{"type":6,"name":20,"description":20,"armGroupLabels":21,"otherNames":10},"no intervention is given",[15,9],[23],{"name":24,"affiliation":25,"role":26},"Frank Behrens, MD","Fraunhofer IME","PRINCIPAL_INVESTIGATOR",[28],{"facility":29,"status":10,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":10},"CIRI","Frankfurt am Main","Hessia","60596","Germany","DE",{"type":36,"coordinates":37},"Point",[38,39],8.68417,50.11552,{"lat":39,"lon":38},{"type":26,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Dr. Frank Behrens","Head of clinical research department",[45,48],{"name":46,"class":47},"Bristol-Myers Squibb","INDUSTRY",{"name":49,"class":6},"Goethe University","100306278","prevalence-of-anti-ccp-positivity-and-subclinical-signs-of-inflammation-in-patients-with-new-onset-of-non-specific-musculoskeletal-symptoms-100306278",false,"NCT03267147","PREVALENCE OF Anti-CCP POSITIVITY AND SUBCLINICAL SIGNS OF INFLAMMATION IN PATIENTS WITH NEW ONSET OF NON-SPECIFIC MUSCULOSKELETAL SYMPTOMS","PREVALENCE OF ANTI-CYCLIC CITRULLINATED PEPTIDE (Anti-CCP) POSITIVITY AND SUBCLINICAL SIGNS OF INFLAMMATION IN PATIENTS WITH NEW ONSET OF NON-SPECIFIC MUSCULOSKELETAL SYMPTOMS POSSIBLY RELATED TO EARLY RHEUMATOID ARTHRITIS IN GENERAL PRACTICES IN GERMANY","PANORA","Inclusion Criteria:\n\n* New onset of non-specific MSK symptoms, including, but not limited to, arthralgia of the hands and the large joints such as wrists, knees, and shoulders\n* Written informed consent obtained prior to the initiation of any study protocol-required procedures\n* General understanding of study procedure and informed consent\n* Age ≥ 18 and ≤ 65 years\n\nExclusion Criteria:\n\n* RA diagnosed according to modified EULAR\u002FACR (american college of rheumatology)-criteria\n* Other known arthritis\n* Other known reasons for MSK symptoms, e.g. mechanical, traumatic, etc.\n* MSK symptoms previously reported at another (general) practice\n* Alcohol, drug or chemical abuse\n* Underage or incapable patients","ALL","18 Years","65 Years",{"count":62,"type":63},986,"ACTUAL","OBSERVATIONAL","Non-interventional, prospective, observational study to assess the relative risk of anti-CCP positive patients to develop (subclinical) signs of inflammation in accordance with early Rheumatoid Arthritis (RA) in a population without pre-classified RA but new1 onset of non-specific musculoskeletal (MSK) symptoms in general practices in Germany and subsequent 36 months follow-up by rheumatologists",[67],"Rheumatoid Arthritis",[69,70],"Anti-CCP","rheumatoid arthritis","COMPLETED","2022-03-01",{"date":74,"type":63},"2022-03-02",{"date":76,"type":63},"2017-04-27",{"date":78,"type":63},"2022-02-15",{"name":5,"class":6},1]