[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100457167":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":22,"locations":28,"responsibleParty":42,"collaborators":44,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":22,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":70,"whyStopped":22,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Fracture","Patients with a fracture of the upper neck of the femur",[12],"Other: Blood sample",{"label":14,"type":6,"description":15,"interventionNames":16},"Control","Patients with no fracture of the upper neck of the femur",[12],[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"Blood sample","Arm 'Fracture':1 blood sample at D0, D1, D3, D7 and D30 Arm 'Control': 1 blood sample at D0",[14,9],null,[24],{"name":25,"affiliation":26,"role":27},"Jacques BODDAERT, MD","GH Pitié Salpêtrière - Charles Foix","PRINCIPAL_INVESTIGATOR",[29],{"facility":30,"status":22,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":22},"GH Pitié-Salpêtrière \u002F Service de gériatrie","Paris","Île-de-France Region","75013","France","FR",{"type":37,"coordinates":38},"Point",[39,40],2.3488,48.85341,{"lat":40,"lon":39},{"type":43,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR",[45],{"name":46,"class":47},"Institut National de la Santé Et de la Recherche Médicale, France","OTHER_GOV","100457167","prognostic-impact-of-neopterin-on-resumption-of-walking-after-a-fracture-of-the-upper-neck-of-the-femur-in-the-elderly-100457167",false,"NCT05233072","Prognostic Impact of Neopterin on Resumption of Walking After a Fracture of the Upper Neck of the Femur in the Elderly","MAMI","Inclusion Criteria:\n\nFor both arms:\n\n* age over 75\n* affiliated to health insurance system\n* written informed consent\n\nFor arm 'Fracture':\n\n* patient with a fracture of the upper neck of the femur\n* hospitalized in emergency in a 'UPOG' unit\n\nFor arm 'control':\n\n* hospitalized patient without any acute clinical event\n\nExclusion Criteria:\n\nFor both arms:\n\n* polytrauma\n* pathological bone or prothesis fracture\n* patient affiliated to 'Aide Médical de l'Etat - AME' insurance\n* patient with immunosuppressant treatment (including corticotherapy over 5 mg\u002Fd)\n* patient with active solid cancer or malignant haemopathy\n* patient with auto-immune disease\n* refusal to participate in research\n\nFor arm 'Fracture':\n\n* patient under justice protection measure except tutorship and guardianship\n\nFor arm 'control':\n\n* severe neurocognitive disorders (MMS \\\u003C 15)\n* fracture of the upper neck of the femur in the last year\n* patient under justice protection measure","ALL","75 Years","110 Years",{"count":59,"type":60},150,"ESTIMATED","INTERVENTIONAL",[63],"NA","Society faces a major challenge with the management of the health and socio-economic burden caused by acute physical stress in the older population (\\>75 years). In particular, hip fracture (HF) represents a major health care preoccupation, affecting 1.6 M patients worldwide, resulting in a significant drop of life quality and autonomy. Nowadays, this trauma is still associated with a poor outcome of 20-30% one-year mortality in the elderly. This emphasizes the value of assessing biological factors that may predict clinical outcome after HF. The preliminary work pinpoints a central role of neopterin in loss of autonomy and death. Using HF as an acute stress model that accelerates the progressive course of aging, the aim is to validate neopterin as a predictive biomarker of pernicious clinical outcomes.",[66,67],"Fracture of Neck of Femur","Resumption of Walking",[69],"Neopterin","ACTIVE_NOT_RECRUITING","2025-02-13",{"date":73,"type":74},"2025-02-17","ACTUAL",{"date":76,"type":74},"2022-05-16",{"date":78,"type":60},"2025-09",{"name":5,"class":6},1]