[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100165881":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":7,"locations":17,"responsibleParty":30,"collaborators":7,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":38,"eligibilityCriteria":39,"healthyVolunteers":34,"sex":40,"minAge":41,"maxAge":7,"enrollmentInfo":42,"targetDuration":7,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":51,"overallStatus":64,"whyStopped":7,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Nantes University Hospital","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Prediabetes screening and prospective follow-up over 5 years","The study period per patient is 5 years. The planned schedule of the study is as follows :\n\n* Enrollment at visit V0 of subjects at high metabolic risk, based on a biological value (within the past 2 months) of moderate fasting hyperglycaemia (blood glucose ≥ 1,10 g\u002Fl and \\\u003C 1,26 g\u002Fl) or fasting blood glucose ≥ 1 g\u002Fl and \\\u003C 1,10 g\u002Fl with HbA1c ≥ 6,5%.\n* First biological sample (B0) within 1 month following V0 (measuring fasting blood glucose + glycated hemoglobin HbA1c + lipid profile + creatinemia + liver function; and establishment of a biological sample collection to identify biomarkers).\n* Annual follow-up for five years consisting in one blood sample (B1 to B5) measuring the same parameters as V0 + biological sample collection, and questionnaire on major health events or health events related to study procedures.\n* End of study phone call",[13],{"name":14,"affiliation":15,"role":16},"Bertrand Cariou, Pr.","University Hospital of Nantes, France","PRINCIPAL_INVESTIGATOR",[18],{"facility":19,"status":7,"city":20,"state":7,"zip":21,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":7},"Clinical Nutrition Center Naturalpha (CNCN)","Lille","59020","France","FR",{"type":25,"coordinates":26},"Point",[27,28],3.05512,50.63391,{"lat":28,"lon":27},{"type":31,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100165881","prospective-follow-up-of-a-cohort-of-pre-diabetics-in-the-north-of-france-diabenord-100165881",false,"NCT01432509","Prospective Follow-up of a Cohort of Pre-diabetics in the North of France (DiabeNord)","DiabeNord: A 5-year Prospective Follow-up Cohort Study in Pre-diabetic Subjects for the Identification of New Biomarkers","DiabeNord","Inclusion Criteria:\n\n* Previous history (within 2 months prior to enrollment visit) of fasting blood glucose ≥ 1,10 g\u002Fl and \\\u003C 1,26 g\u002Fl OR fasting blood glucose ≥ 1 g\u002Fl and \\\u003C 1,10 g\u002Fl with HbA1c ≥ 6,5%.\n\nExclusion Criteria:\n\n* Fasting glycemia ≥ 1.26 g\u002Fl\n* History of treatment with oral antidiabetics\n* History of treatment with insulin, except gestational diabetes\n* Subject with any history or presence of significant hematologic (coagulation, thrombopenia, …), hepatic, renal, or psychiatric disorders\n* Subject unable to follow the study during the 5 years of follow-up\n* Subject in exclusion period of a previous study or simultaneously participating to any other clinical trial on metabolism","ALL","18 Years",{"count":43,"type":44},207,"ACTUAL","INTERVENTIONAL",[47],"NA","The purpose of this study is to identify in prediabetic subjects, physiopathological changes involved in the evolution to type 2 diabetes mellitus and to identify new biomarkers of type 2 diabetes risk in this population.",[50],"Prediabetes",[52,53,54,55,56,57,58,59,60,61,62,63],"Pre-diabetes","Type 2 diabetes","Biomarkers","Cohort","Diabetes Risk Score","Diabetes Mellitus, Type 2","Glucose Intolerance","Prediabetic State","Glucose Metabolism Disorders","Metabolic Diseases","Endocrine System Diseases","Hyperglycemia","COMPLETED","2018-04-05",{"date":67,"type":44},"2018-04-06",{"date":69,"type":7},"2011-09",{"date":71,"type":44},"2017-11-23",{"name":5,"class":6},1]