[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100503565":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":26,"locations":34,"responsibleParty":48,"collaborators":52,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":26,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":26,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":26,"overallStatus":74,"whyStopped":26,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Sun Yat-sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Swisse Plus cholesterol capsules","EXPERIMENTAL","(the main components are red yeast rice, phytosterol esters and lycopene)，the capsule is orally taken twice a day,two,tablets at a time 12 weeks",[13],"Dietary Supplement: Swisse plus cholesterol capsule",{"label":15,"type":16,"description":17,"interventionNames":18},"placebo contral","PLACEBO_COMPARATOR","The placebo is an excipient and the colos, flavor, shape and weight are same with the Swisse plus cholesterol capsule",[19],"Dietary Supplement: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Swisse plus cholesterol capsule","Swisse plus cholesterol capsule per day orally for 12 weeks",[9],null,{"type":22,"name":28,"description":28,"armGroupLabels":29,"otherNames":26},"Placebo",[15],[31],{"name":32,"affiliation":5,"role":33},"Lili Yang, Professor","STUDY_CHAIR",[35],{"facility":36,"status":26,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":26},"SunYat-senU","Guanzhou","Guangdong","510080","China","CN",{"type":43,"coordinates":44},"Point",[45,46],113.37117,23.06828,{"lat":46,"lon":45},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Lili Yang","head of Department of Nutrition, School of Public Health, Sun Yat-sen University",[53],{"name":5,"class":6},"100503565","regulation-of-lipid-metabolism-in-guangzhou-individuals-with-dyslipidemia-by-red-yeast-rice-phytosterol-esters-and-lycopene-100503565",false,"NCT05836909","Regulation of Lipid Metabolism in Guangzhou Individuals With Dyslipidemia by Red Yeast Rice, Phytosterol Esters and Lycopene","A Randomized, Double-blind, Placebo-controlled Trial of Using Red Yeast Rice, Phytosterol Esters and Lycopene in Combination for Regulating Lipid Metabolism of Guangzhou Individuals With Dyslipidemia","Inclusion Criteria:\n\n1. Age: 30-50 years old.\n2. Non-obese individuals: 18.5 ≤ BMI \\\u003C 28.\n3. Total cholesterol levels ranging from marginal increase to increase: 6.2\\> TC ≥ 5.2 mmol\u002FL (200 mg\u002FdL).\n\nExclusion Criteria:\n\n1. Currently being pregnant or breast-feeding or planning to become pregnant.\n2. Having severe complications of diabetes mellitus as well as any forms of cardiovascular diseases, tumor, liver diseases and kidney diseases.\n3. History (past 3 months) of intake of lipid-lowering or anti-diabetic health care products.\n4. Having hemorrhagic diathesis (high bleeding tendencies) or currently taking aspirin.\n5. Unwilling\u002Funable to draw blood due to physical\u002Fpersonal reasons.\n6. History (past 1 month) of surgery.\n7. History (past 1 month) of large amounts of oral or intravenous treatment of glucocorticoids (such as prednisone, methylprednisone, betamethasone, beclomethasone propionate, Dubossone, prednisone, hydrocodesone, dexamethasone).\n8. History (past 2 weeks) of taking supplements containing red yeast rice, phytosterol ester or lycopene.\n9. Unqualified outcomes of safety measures at baseline.",true,"ALL","30 Years","50 Years",{"count":66,"type":67},80,"ESTIMATED","INTERVENTIONAL",[70],"NA","The objective of this study is to evaluate the effect of using red yeast rice, phytosterol esters and lycopene in combination for 12 weeks on improving the glycolipid metabolism of Guangzhou individuals with dyslipidemia. Our hypothesis is that when compared with placebo, red yeast rice, phytosterol esters and lycopene together as supplements would lead to greater improvements in lipid metabolism (including lipid profiles and parameters ) in participants after 12 weeks.",[73],"Hypercholesterolemia","UNKNOWN","2023-06-16",{"date":77,"type":78},"2023-06-18","ACTUAL",{"date":80,"type":78},"2023-05-01",{"date":82,"type":67},"2024-04-30",{"name":50,"class":6},1]