[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100154354":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":21,"centralContacts":7,"locations":29,"responsibleParty":52,"collaborators":7,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":7,"studyType":69,"phases":7,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":78,"whyStopped":7,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"ETOP IBCSG Partners Foundation","NETWORK",null,[9,13,17],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"GENETIC","polymorphism analysis","SNPs will be genotyped in whole blood samples taken at baseline.",{"type":14,"name":15,"description":16,"armGroupLabels":7,"otherNames":7},"OTHER","laboratory biomarker analysis","Biomarkers will be assessed in blood and serum samples at different time points.",{"type":18,"name":19,"description":20,"armGroupLabels":7,"otherNames":7},"PROCEDURE","quality-of-life assessment","Quality of life will be assessed using the Breast Cancer Prevention Trial (BCPT) Symptom Scales and the IBCSG Trial 35-07 QL Form.",[22,26],{"name":23,"affiliation":24,"role":25},"Jacquie Chirgwin, MD","Box Hill Hospital","STUDY_CHAIR",{"name":27,"affiliation":28,"role":25},"Guy Jerusalem, MD, PhD","CHU Liege - Domaine Universitaire du Sart Tilman",[30,42],{"facility":24,"status":7,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":7},"Box Hill","Victoria","3128","Australia","AU",{"type":37,"coordinates":38},"Point",[39,40],145.12545,-37.81887,{"lat":40,"lon":39},{"facility":28,"status":7,"city":43,"state":7,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":51,"contacts":7},"Liège","B-4000","Belgium","BE",{"type":37,"coordinates":48},[49,50],5.56749,50.63373,{"lat":50,"lon":49},{"type":53,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100154354","study-of-changes-in-estrogen-levels-and-grip-strength-in-postmenopausal-women-who-have-received-4-to-6-years-of-hormone-therapy-for-breast-cancer-and-are-currently-receiving-letrozole-on-clinical-trial-ibcsg-35-07-100154354",true,"NCT01281137","Study of Changes in Estrogen Levels and Grip Strength in Postmenopausal Women Who Have Received 4 to 6 Years of Hormone Therapy for Breast Cancer and Are Currently Receiving Letrozole on Clinical Trial IBCSG-35-07","SOLE Estrogen Substudy (SOLE-EST) - Investigating Changes in Estrogen Levels and Grip Strength for Patients Participating in the SOLE Trial","SOLE-EST","DISEASE CHARACTERISTICS:\n\n* Previously diagnosed with breast cancer\n\n  * Endocrine-responsive, node-positive, resectable disease\n* Disease-free following 4-6 years of prior adjuvant endocrine therapy with selective estrogen-receptor modulators and\u002For aromatase inhibitors\n* Patient must be currently enrolled on clinical trial IBCSG-35-07 as well as the Quality-of-Life substudy\n* Hormone receptor status not specified\n\nPATIENT CHARACTERISTICS:\n\n* Postmenopausal\n\nPRIOR CONCURRENT THERAPY:\n\n* See Disease Characteristics",false,"FEMALE","18 Years","120 Years",{"count":67,"type":68},104,"ACTUAL","OBSERVATIONAL","RATIONALE: Studying samples of blood in the laboratory from patients receiving treatment for cancer may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.\n\nPURPOSE: This clinical trial is studying changes in estrogen levels and grip strength in postmenopausal women who have received 4 to 6 years of hormone therapy for breast cancer and are currently receiving letrozole on clinical trial IBCSG-35-07.",[72],"Breast Cancer",[74,75,76,77],"stage IA breast cancer","stage IB breast cancer","stage II breast cancer","stage IIIA breast cancer","COMPLETED","2021-09-08",{"date":81,"type":68},"2021-10-06",{"date":83,"type":68},"2011-01",{"date":85,"type":68},"2019-05-15",{"name":5,"class":6},2]