[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100269606":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":7,"locations":12,"responsibleParty":227,"collaborators":229,"id":232,"slug":233,"hasResults":234,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":238,"eligibilityCriteria":239,"healthyVolunteers":240,"sex":241,"minAge":242,"maxAge":7,"enrollmentInfo":243,"targetDuration":246,"studyType":247,"phases":7,"briefSummary":248,"conditions":249,"keywords":251,"overallStatus":253,"whyStopped":7,"lastUpdateSubmitDate":254,"lastUpdatePostDateStruct":255,"startDateStruct":257,"completionDateStruct":259,"leadSponsor":261,"locationsCount":262},{"fullName":5,"class":6},"Pfizer","INDUSTRY",null,[9],{"name":10,"affiliation":5,"role":11},"Pfizer CT.gov Call Center","STUDY_DIRECTOR",[13,26,36,45,55,65,75,85,94,102,111,120,129,138,147,156,165,174,183,192,200,209,218],{"facility":14,"status":7,"city":15,"state":16,"zip":17,"country":18,"countryCode":19,"cosmosGeoPoint":20,"geoPoint":25,"contacts":7},"Hospital Arquitecto Marcide de Ferrol","Ferrol","A Coruña","15405","Spain","ES",{"type":21,"coordinates":22},"Point",[23,24],-8.23293,43.48451,{"lat":24,"lon":23},{"facility":27,"status":7,"city":28,"state":29,"zip":30,"country":18,"countryCode":19,"cosmosGeoPoint":31,"geoPoint":35,"contacts":7},"Hospital Asil de Granollers","Granollers","Barcelona","08402",{"type":21,"coordinates":32},[33,34],2.28773,41.60797,{"lat":34,"lon":33},{"facility":37,"status":7,"city":38,"state":29,"zip":39,"country":18,"countryCode":19,"cosmosGeoPoint":40,"geoPoint":44,"contacts":7},"Hospital Parc Taulí","Sabadell","08208",{"type":21,"coordinates":41},[42,43],2.10942,41.54329,{"lat":43,"lon":42},{"facility":46,"status":7,"city":47,"state":48,"zip":49,"country":18,"countryCode":19,"cosmosGeoPoint":50,"geoPoint":54,"contacts":7},"Hospital Galdakano","Usansolo","Bizkaia","48960",{"type":21,"coordinates":51},[52,53],-2.81567,43.22166,{"lat":53,"lon":52},{"facility":56,"status":7,"city":57,"state":58,"zip":59,"country":18,"countryCode":19,"cosmosGeoPoint":60,"geoPoint":64,"contacts":7},"Complejo Hospitalario la Mancha Centro","Alcázar de San Juan","Ciudad REAL","13600",{"type":21,"coordinates":61},[62,63],-3.20827,39.39011,{"lat":63,"lon":62},{"facility":66,"status":7,"city":67,"state":68,"zip":69,"country":18,"countryCode":19,"cosmosGeoPoint":70,"geoPoint":74,"contacts":7},"Hospital Universitari Son Espases","Palma","Mallorca","07120",{"type":21,"coordinates":71},[72,73],2.65024,39.56939,{"lat":73,"lon":72},{"facility":76,"status":7,"city":77,"state":78,"zip":79,"country":18,"countryCode":19,"cosmosGeoPoint":80,"geoPoint":84,"contacts":7},"Hospital Universitario Sant Joan de Reus \u002F Servicio de Oncología Médica","Reus","Tarragona","43204",{"type":21,"coordinates":81},[82,83],1.10687,41.15612,{"lat":83,"lon":82},{"facility":86,"status":7,"city":87,"state":7,"zip":88,"country":18,"countryCode":19,"cosmosGeoPoint":89,"geoPoint":93,"contacts":7},"H. Universitario Infanta Cristina","Badajoz","06006",{"type":21,"coordinates":90},[91,92],-6.97061,38.87789,{"lat":92,"lon":91},{"facility":95,"status":7,"city":29,"state":7,"zip":96,"country":18,"countryCode":19,"cosmosGeoPoint":97,"geoPoint":101,"contacts":7},"Hospital Vall de Hebrón","08035",{"type":21,"coordinates":98},[99,100],2.15899,41.38879,{"lat":100,"lon":99},{"facility":103,"status":7,"city":104,"state":7,"zip":105,"country":18,"countryCode":19,"cosmosGeoPoint":106,"geoPoint":110,"contacts":7},"Hospital Universitario Ciudad Real","Ciudad Real","13005",{"type":21,"coordinates":107},[108,109],-3.92907,38.98626,{"lat":109,"lon":108},{"facility":112,"status":7,"city":113,"state":7,"zip":114,"country":18,"countryCode":19,"cosmosGeoPoint":115,"geoPoint":119,"contacts":7},"H. Reina Sofía de Cordoba","Córdoba","14004",{"type":21,"coordinates":116},[117,118],-4.77275,37.89155,{"lat":118,"lon":117},{"facility":121,"status":7,"city":122,"state":7,"zip":123,"country":18,"countryCode":19,"cosmosGeoPoint":124,"geoPoint":128,"contacts":7},"ICO Girona (Hospital Dr.Josep Trueta)","Girona","17007",{"type":21,"coordinates":125},[126,127],2.82493,41.98311,{"lat":127,"lon":126},{"facility":130,"status":7,"city":131,"state":7,"zip":132,"country":18,"countryCode":19,"cosmosGeoPoint":133,"geoPoint":137,"contacts":7},"Complejo Hospitalario de Jaén","Jaén","23007",{"type":21,"coordinates":134},[135,136],-3.79028,37.76922,{"lat":136,"lon":135},{"facility":139,"status":7,"city":140,"state":7,"zip":141,"country":18,"countryCode":19,"cosmosGeoPoint":142,"geoPoint":146,"contacts":7},"Complejo Hospitalario de León","León","24071",{"type":21,"coordinates":143},[144,145],-5.57032,42.60003,{"lat":145,"lon":144},{"facility":148,"status":7,"city":149,"state":7,"zip":150,"country":18,"countryCode":19,"cosmosGeoPoint":151,"geoPoint":155,"contacts":7},"Hospital Universitario La Princesa \u002F Servicio de Oncología Médica","Madrid","28006",{"type":21,"coordinates":152},[153,154],-3.70256,40.4165,{"lat":154,"lon":153},{"facility":157,"status":7,"city":158,"state":7,"zip":159,"country":18,"countryCode":19,"cosmosGeoPoint":160,"geoPoint":164,"contacts":7},"Complejo Hospitalario Ourense. Hospital Santa María Nai","Ourense","32005",{"type":21,"coordinates":161},[162,163],-7.86407,42.33669,{"lat":163,"lon":162},{"facility":166,"status":7,"city":167,"state":7,"zip":168,"country":18,"countryCode":19,"cosmosGeoPoint":169,"geoPoint":173,"contacts":7},"Hospital General de Asturias","Oviedo","33011",{"type":21,"coordinates":170},[171,172],-5.84476,43.36029,{"lat":172,"lon":171},{"facility":175,"status":7,"city":176,"state":7,"zip":177,"country":18,"countryCode":19,"cosmosGeoPoint":178,"geoPoint":182,"contacts":7},"Complejo Hospitalario de Navarra","Pamplona","31008",{"type":21,"coordinates":179},[180,181],-1.64323,42.81687,{"lat":181,"lon":180},{"facility":184,"status":7,"city":185,"state":7,"zip":186,"country":18,"countryCode":19,"cosmosGeoPoint":187,"geoPoint":191,"contacts":7},"Hospital Universitario Canarias","Santa Cruz de Tenerife","38320",{"type":21,"coordinates":188},[189,190],-16.25462,28.46824,{"lat":190,"lon":189},{"facility":193,"status":7,"city":78,"state":7,"zip":194,"country":18,"countryCode":19,"cosmosGeoPoint":195,"geoPoint":199,"contacts":7},"Hospital de Sant Pau i Santa Tecla","43003",{"type":21,"coordinates":196},[197,198],1.24544,41.11905,{"lat":198,"lon":197},{"facility":201,"status":7,"city":202,"state":7,"zip":203,"country":18,"countryCode":19,"cosmosGeoPoint":204,"geoPoint":208,"contacts":7},"Hospital Virgen de la Salud","Toledo","45071",{"type":21,"coordinates":205},[206,207],-4.02263,39.8581,{"lat":207,"lon":206},{"facility":210,"status":7,"city":211,"state":7,"zip":212,"country":18,"countryCode":19,"cosmosGeoPoint":213,"geoPoint":217,"contacts":7},"Hospital Clínico Universitario de Valencia","Valencia","46011",{"type":21,"coordinates":214},[215,216],-0.37966,39.47391,{"lat":216,"lon":215},{"facility":219,"status":7,"city":220,"state":7,"zip":221,"country":18,"countryCode":19,"cosmosGeoPoint":222,"geoPoint":226,"contacts":7},"H Clínico Zaragoza","Zaragoza","50009",{"type":21,"coordinates":223},[224,225],-0.87734,41.65606,{"lat":225,"lon":224},{"type":228,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[230],{"name":231,"class":6},"TFS Trial Form Support","100269606","study-on-fatigue--and-hand-foot-syndrome-related-quality-of-life-in-patients-with-metastatic-renal-cell-carcinoma-receiving-a-tyrosine-kinase-inhibitor-as-first-line-treatment-100269606",true,"NCT02789137","Study On Fatigue- And Hand-Foot Syndrome-Related Quality Of Life In Patients With Metastatic Renal Cell Carcinoma Receiving A Tyrosine Kinase Inhibitor as First-Line Treatment","PROSPECTIVE, MULTICENTRE, OBSERVATIONAL STUDY ON FATIGUE- AND HAND-FOOT SYNDROME-RELATED QUALITY OF LIFE IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA RECEIVING A TYROSINE KINASE INHIBITOR AS FIRST-LINE TREATMENT (TROYA STUDY).","TROYA","Inclusion Criteria:\n\n* Patients ≥ 18 years old and diagnosed with metastatic RCC who, in the investigator's opinion, are candidates for starting first-line treatment with a tyrosine kinase inhibitor according to routine clinical practice.\n* Patients who have no contraindications to the treatment.\n* Baseline ECOG ≤ 2.\n* Patients who are able to give informed consent on their own without the need for a legal representative.\n* Committed patients who are able to complete the quality of life questionnaires and patient diary on their own without the need for a legal representative.\n\nExclusion Criteria:\n\n* Patients who are not candidates for first-line treatment with a tyrosine kinase inhibitor.\n* Patients who are receiving the treatment as second-line or subsequent therapy.\n* Untreated hypothyroidism.\n* Untreated severe anaemia.\n* Pregnancy or breast-feeding.\n* Myocardial infarction or cerebrovascular accidents (CVA) within the last 6 months.\n* Severe hepatic impairment.\n* Concomitant use of potent inhibitors or inducers that interact with hepatic cytochrome CYP3A4.",false,"ALL","18 Years",{"count":244,"type":245},111,"ACTUAL","9 Months","OBSERVATIONAL","The purpose of this study is to know about the quality of life of patients with metastatic renal cell carcinoma who are being treated with sunitinib, pazopanib or sorafenib, and who suffer from fatigue and hand-foot syndrome, with personal inter-variability, and to explore measures that can be taken in terms of both everyday lifestyle and treatment to mitigate or cure such side effects that affect patients.",[250],"Metastatic Renal Cell Carcinoma",[252],"metastatic renal cell carcinoma","COMPLETED","2021-10-06",{"date":256,"type":245},"2021-11-05",{"date":258,"type":245},"2016-12-22",{"date":260,"type":245},"2020-10-20",{"name":5,"class":6},23]