[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100260715":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":19,"locations":20,"responsibleParty":33,"collaborators":19,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":39,"acronym":19,"eligibilityCriteria":40,"healthyVolunteers":37,"sex":41,"minAge":42,"maxAge":19,"enrollmentInfo":43,"targetDuration":19,"studyType":46,"phases":47,"briefSummary":49,"conditions":50,"keywords":52,"overallStatus":58,"whyStopped":19,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},{"fullName":5,"class":6},"Western Galilee Hospital-Nahariya","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"HDF online","OTHER","All patients were started on HF (high-flux) hemodialysis. After 6 months they were then treated by HDF online.",[13],"Procedure: HDF online",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"PROCEDURE","Hemodialysis by the HDF online method",[9],null,[21],{"facility":22,"status":19,"city":23,"state":19,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":19},"Western Galilee Hospital","Nahariya","22100","Israel","IL",{"type":28,"coordinates":29},"Point",[30,31],35.09814,33.00892,{"lat":31,"lon":30},{"type":34,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100260715","the-benefit-of-n-line-high-convection-volume-hemodiafiltration-treatment-versus-high-flow-dialysis-on-reduction-of-oxidative-stress-and-health-related-quality-of-life-in-dialysis-patients-100260715",false,"NCT02673099","The Benefit of Оn-Line High Convection Volume Hemodiafiltration Treatment Versus High Flow Dialysis on Reduction of Oxidative Stress and Health Related Quality of Life in Dialysis Patients","Inclusion Criteria:\n\n* On chronic hemodialysis more than 3 months\n\nExclusion Criteria:\n\n* No exclusions","ALL","18 Years",{"count":44,"type":45},45,"ACTUAL","INTERVENTIONAL",[48],"NA","Introduction: Patients with end stage renal disease are exposed to metabolic and hemodynamic complications due to the disease itself and as a result of the dialysis treatment related complications. Uremic toxins due to their middle molecular weight are not effectively removed during Hemodialysis. Their accumulation leads to chronic oxidative stress and chronic inflammation state associated with increased morbidity and mortality. In addition, during each dialysis session oxidative stress (OS) and inflammation are provoked once blood interacts with the dialyzer.\n\nIn recent years the use of Online Hemodiafiltration (OL- HDF) has entered in order to enable better uremic toxins clearance. This a relatively new method of therapy that allows a larger volume of blood filtration during a single dialysis therapy compared with standard hemodialysis. It combines diffusion with convection to clear middle molecular weight substances more effectively compared with Hemodialysis. This method was found to reduce rates of cardiovascular morbidity and mortality among dialysis patients.",[51],"End Stage Renal Disease",[9,53,54,55,56,57],"ESRD","Hemodialysis","oxidative stress","quality of life","Hemodialysis treatment","COMPLETED","2017-05-08",{"date":61,"type":45},"2017-05-09",{"date":63,"type":19},"2013-08",{"date":65,"type":45},"2017-02-01",{"name":5,"class":6},1]